CASI vs. KLAC

Last updated Apr 1, 2026

Compare and contrast key facts about CASI Pharmaceuticals, Inc. (CASI) and KLA Corporation (KLAC).

Performance

CASI vs. KLAC - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in CASI Pharmaceuticals, Inc. (CASI) and KLA Corporation (KLAC). The values are adjusted to include any dividend payments, if applicable.

CASI vs. KLAC - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
CASI CASI Pharmaceuticals, Inc.	-75.59%	-69.96%	-60.47%	300.00%	-77.62%	-72.88%	-4.53%	-23.13%	23.69%	182.61%
KLAC KLA Corporation	21.34%	94.48%	9.36%	56.05%	-11.20%	68.05%	47.94%	103.99%	-12.49%	36.80%

Fundamentals

Market Cap CASI : $3.33M KLAC : $194.66B
EPS CASI : -$3.13 KLAC : $34.42
PS Ratio CASI : 0.12 KLAC : 15.30
Total Revenue (TTM) CASI : $26.85M KLAC : $12.74B
Gross Profit (TTM) CASI : $9.61M KLAC : $7.89B
EBITDA (TTM) CASI : -$41.37M KLAC : $5.71B

Returns By Period

In the year-to-date period, CASI achieves a -75.59% return, which is significantly lower than KLAC's 21.34% return. Over the past 10 years, CASI has underperformed KLAC with an annualized return of -32.65%, while KLAC has yielded a comparatively higher 37.36% annualized return.

CASI

• 1D: 0.00%
• 1M: 0.00%
• YTD: -75.59%
• 6M: -87.50%
• 1Y: -90.39%
• 3Y*: -55.28%
• 5Y*: -60.83%
• 10Y*: -32.65%

KLAC

• 1D: 6.50%
• 1M: -3.42%
• YTD: 21.34%
• 6M: 36.92%
• 1Y: 118.24%
• 3Y*: 55.93%
• 5Y*: 34.90%
• 10Y*: 37.36%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

CASI vs. KLAC — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

CASI

CASI Risk / Return Rank: 6
CASI Sharpe Ratio Rank: 11
CASI Sortino Ratio Rank: 8
CASI Omega Ratio Rank: 5
CASI Calmar Ratio Rank: 3
CASI Martin Ratio Rank: 2

KLAC

KLAC Risk / Return Rank: 93
KLAC Sharpe Ratio Rank: 94
KLAC Sortino Ratio Rank: 89
KLAC Omega Ratio Rank: 91
KLAC Calmar Ratio Rank: 95
KLAC Martin Ratio Rank: 96

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

CASI vs. KLAC - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for CASI Pharmaceuticals, Inc. (CASI) and KLA Corporation (KLAC). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	CASI	KLAC	Difference
Sharpe ratio Return per unit of total volatility	-0.72	2.41	-3.13
Sortino ratio Return per unit of downside risk	-1.30	2.74	-4.04
Omega ratio Gain probability vs. loss probability	0.79	1.40	-0.61
Calmar ratio Return relative to maximum drawdown	-0.98	5.37	-6.35
Martin ratio Return relative to average drawdown	-1.89	17.17	-19.06
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

CASI vs. KLAC - Sharpe Ratio Comparison

The current CASI Sharpe Ratio is -0.72, which is lower than the KLAC Sharpe Ratio of 2.41. The chart below compares the historical Sharpe Ratios of CASI and KLAC, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	CASI	KLAC	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.72	2.41	-3.13
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.61	0.82	-1.43
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.36	0.92	-1.28
Sharpe Ratio (All Time) Calculated using the full available price history	-0.22	0.43	-0.64

Correlation

The correlation between CASI and KLAC is 0.15, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

CASI vs. KLAC - Dividend Comparison

CASI has not paid dividends to shareholders, while KLAC's dividend yield for the trailing twelve months is around 0.52%.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
CASI CASI Pharmaceuticals, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
KLAC KLA Corporation	0.52%	0.61%	0.96%	0.92%	1.25%	0.91%	1.35%	1.74%	3.17%	2.15%	2.67%	2.94%

Drawdowns

CASI vs. KLAC - Drawdown Comparison

The maximum CASI drawdown since its inception was -100.00%, which is greater than KLAC's maximum drawdown of -83.74%. Use the drawdown chart below to compare losses from any high point for CASI and KLAC.

Drawdown Indicators

	CASI	KLAC	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-83.74%	-16.26%
Max Drawdown (1Y) Largest decline over 1 year	-91.60%	-22.41%	-69.19%
Max Drawdown (5Y) Largest decline over 5 years	-99.08%	-40.28%	-58.80%
Max Drawdown (10Y) Largest decline over 10 years	-99.75%	-40.28%	-59.47%
Current Drawdown Current decline from peak	-100.00%	-12.49%	-87.51%
Average Drawdown Average peak-to-trough decline	-90.15%	-29.47%	-60.68%
Ulcer Index Depth and duration of drawdowns from previous peaks	47.65%	7.00%	+40.65%

Volatility

CASI vs. KLAC - Volatility Comparison

The current volatility for CASI Pharmaceuticals, Inc. (CASI) is 0.00%, while KLA Corporation (KLAC) has a volatility of 17.00%. This indicates that CASI experiences smaller price fluctuations and is considered to be less risky than KLAC based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	CASI	KLAC	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.00%	17.00%	-17.00%
Volatility (6M) Calculated over the trailing 6-month period	146.08%	37.03%	+109.05%
Volatility (1Y) Calculated over the trailing 1-year period	126.70%	49.32%	+77.38%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	100.17%	42.63%	+57.54%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	90.74%	40.93%	+49.81%

Financials