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Arrowhead Pharmaceuticals, Inc. (ARWR)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

US04280A1007

CUSIP

04280A100

IPO Date

Jun 16, 1993

Highlights

Market Cap

$1.92B

EPS (TTM)

-$5.15

PEG Ratio

-1.32

Total Revenue (TTM)

$2.50M

Gross Profit (TTM)

-$7.52M

EBITDA (TTM)

-$465.46M

Year Range

$9.57 - $30.41

Target Price

$45.64

Short %

11.80%

Short Ratio

6.13

Share Price Chart


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Compare to other instruments

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Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Arrowhead Pharmaceuticals, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


0.00%200.00%400.00%600.00%800.00%1,000.00%December2025FebruaryMarchAprilMay
-78.26%
911.24%
ARWR (Arrowhead Pharmaceuticals, Inc.)
Benchmark (^GSPC)

Returns By Period

Arrowhead Pharmaceuticals, Inc. (ARWR) returned -29.52% year-to-date (YTD) and -47.46% over the past 12 months. Over the past 10 years, ARWR returned 7.09% annually, underperforming the S&P 500 benchmark at 10.43%.


ARWR

YTD

-29.52%

1M

32.63%

6M

-38.06%

1Y

-47.46%

5Y*

-17.30%

10Y*

7.09%

^GSPC (Benchmark)

YTD

-3.70%

1M

13.67%

6M

-5.18%

1Y

9.18%

5Y*

14.14%

10Y*

10.43%

*Annualized

Monthly Returns

The table below presents the monthly returns of ARWR, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
20255.74%-4.88%-32.63%9.03%-4.61%-29.52%
20244.90%-0.00%-10.90%-20.91%1.46%13.25%9.89%-16.56%-18.72%-0.72%35.36%-27.78%-38.56%
2023-13.73%-7.69%-21.36%39.41%-2.82%3.63%-3.20%-19.93%-2.79%-8.49%-13.79%44.34%-24.56%
2022-20.42%-16.60%4.52%-10.61%-18.85%5.55%20.79%-6.63%-16.77%5.33%-7.50%25.96%-38.82%
20210.57%3.23%-16.76%9.73%-0.22%14.08%-16.34%-3.13%-6.99%2.23%9.76%-5.35%-13.59%
2020-33.93%-15.63%-18.64%19.67%-6.36%33.96%-0.28%-1.93%1.94%33.07%9.13%22.71%20.97%
201913.69%38.24%-5.99%-2.02%31.87%11.77%9.66%17.58%-17.53%42.12%82.30%-13.12%410.71%
201867.93%4.85%11.27%-10.96%66.98%26.87%7.13%1.30%29.88%-33.65%14.15%-14.46%237.50%
201725.16%16.49%-18.14%-16.22%-7.10%12.50%8.64%59.09%54.64%-15.94%-1.92%3.08%137.42%
2016-43.41%12.07%23.59%20.12%5.87%-13.21%12.03%16.28%6.06%-21.09%-75.17%7.64%-74.80%
2015-14.50%19.33%-10.16%2.00%-8.70%13.49%-13.57%-4.05%-2.87%-10.59%22.72%-2.69%-16.67%
201441.38%26.73%-15.53%-33.50%15.21%13.75%-11.60%15.18%1.37%-55.86%-10.74%26.80%-31.98%

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

The current rank of ARWR is 15, meaning it’s performing worse than 85% of other stocks on our website when it comes to balancing risk and reward. Below is a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of ARWR is 1515
Overall Rank
The Sharpe Ratio Rank of ARWR is 1414
Sharpe Ratio Rank
The Sortino Ratio Rank of ARWR is 1414
Sortino Ratio Rank
The Omega Ratio Rank of ARWR is 1616
Omega Ratio Rank
The Calmar Ratio Rank of ARWR is 2121
Calmar Ratio Rank
The Martin Ratio Rank of ARWR is 99
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for Arrowhead Pharmaceuticals, Inc. (ARWR) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

Arrowhead Pharmaceuticals, Inc. Sharpe ratios as of May 9, 2025 (values are recalculated daily):

  • 1-Year: -0.72
  • 5-Year: -0.26
  • 10-Year: 0.10
  • All Time: -0.03

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

The chart below shows the rolling Sharpe ratio of Arrowhead Pharmaceuticals, Inc. compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time. For deeper analysis or to customize the calculation, use the Sharpe ratio tool.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.00December2025FebruaryMarchAprilMay
-0.72
0.48
ARWR (Arrowhead Pharmaceuticals, Inc.)
Benchmark (^GSPC)

Dividends

Dividend History


Arrowhead Pharmaceuticals, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


-100.00%-80.00%-60.00%-40.00%-20.00%0.00%December2025FebruaryMarchAprilMay
-98.19%
-7.82%
ARWR (Arrowhead Pharmaceuticals, Inc.)
Benchmark (^GSPC)

Worst Drawdowns

The table below displays the maximum drawdowns of the Arrowhead Pharmaceuticals, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Arrowhead Pharmaceuticals, Inc. was 99.83%, occurring on Dec 16, 2016. The portfolio has not yet recovered.

The current Arrowhead Pharmaceuticals, Inc. drawdown is 98.19%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-99.83%Jan 25, 19963716Dec 16, 2016
-75%Dec 8, 199514Dec 29, 199512Jan 22, 199626
-66.67%Sep 28, 19956Oct 31, 19955Nov 20, 199511
-40%Nov 30, 19951Nov 30, 19951Dec 1, 19952
-30%Nov 28, 19951Nov 28, 19951Nov 29, 19952

Volatility

Volatility Chart

The current Arrowhead Pharmaceuticals, Inc. volatility is 26.65%, representing the average percentage change in the investments's value, either up or down over the past month. The chart below shows the rolling one-month volatility.


0.00%5.00%10.00%15.00%20.00%25.00%30.00%35.00%December2025FebruaryMarchAprilMay
26.65%
11.21%
ARWR (Arrowhead Pharmaceuticals, Inc.)
Benchmark (^GSPC)

Financials

Financial Performance

The chart below illustrates the trends in the financial health of Arrowhead Pharmaceuticals, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of Arrowhead Pharmaceuticals, Inc., comparing actual results with analytics estimates. In the past quarter, the company did not meet analyst expectations for EPS, resulting in a surprise of -92.1%.


-1.00-0.500.000.50AprilJulyOctober2021AprilJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober
-1.39
-0.72
Actual
Estimate

Valuation

The Valuation section provides an overview of how Arrowhead Pharmaceuticals, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PEG Ratio

The chart shows the Price/Earnings to Growth (PEG) ratio for ARWR compared to other companies in the Biotechnology industry. ARWR currently has a PEG ratio of -1.3. This PEG ratio is negative, which typically signals that the company's earnings are expected to decline. A negative PEG is not considered meaningful for valuation purposes.

PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for ARWR relative to other companies in the Biotechnology industry. Currently, ARWR has a P/S ratio of 767.9. This P/S ratio is high relative to other companies in the industry. It could mean the stock is overvalued, or that investors expect strong future growth and profitability.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for ARWR in comparison with other companies in the Biotechnology industry. Currently, ARWR has a P/B value of 37.7. This P/B ratio is higher than most companies in the industry. It may suggest the stock is overvalued or that investors expect the company to generate high returns on its assets.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items