- ISIN
- US03828A1016
- CUSIP
- 03828A101
- Sector
- Healthcare
- Industry
- Biotechnology
- IPO Date
- May 14, 2019
Highlights
- Market Cap
- $14.86M
- Enterprise Value
- $5.42M
- EPS (TTM)
- -$0.12
- Total Revenue (TTM)
- $1.00M
- Gross Profit (TTM)
- -$28.46M
- EBITDA (TTM)
- -$100.52M
- Year Range
- $0.09 - $1.50
- Target Price
- $0.25
- ROA (TTM)
- -52.77%
- ROE (TTM)
- 3,233.16%
- Avg. Volume (1M)
- 0
- Avg. Volume Value (1M)
- $0.00
Share Price Chart
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Performance
APLT Performance Chart
Applied Therapeutics, Inc. (APLT) is up 3.0% since the beginning of the year. At $0 per share, APLT is trading 93.1% below its 52-week high of $2. Investors who bought $1,000 worth of APLT shares 5 years ago would now be looking at an investment worth $6.
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Returns By Period
Applied Therapeutics, Inc. (APLT) has returned 3.00% so far this year and -76.63% over the past 12 months.
Applied Therapeutics, Inc.
- 1D
- 0.00%
- 1M
- 0.00%
- 6M
- 0.19%
- YTD
- 3.00%
- 1Y
- -76.63%
- 3Y*
- -60.80%
- 5Y*
- -64.07%
- 10Y*
- —
- ALL TIME*
- -45.34%
Benchmark (S&P 500 Index)
- 1D
- 0.70%
- 1M
- 0.09%
- 6M
- 7.94%
- YTD
- 9.41%
- 1Y
- 20.07%
- 3Y*
- 17.84%
- 5Y*
- 11.25%
- 10Y*
- 13.26%
- ALL TIME*
- 8.09%
APLT Monthly Returns History
Based on dividend-adjusted daily data since May 14, 2019, APLT's average daily return is +0.07%, while the average monthly return is +1.82%. At this rate, an investment would double in approximately 3.2 years.
Historically, 41% of months were positive and 59% were negative. The best month was Feb 2024 with a return of +127.5%, while the worst month was Nov 2025 at -77.4%. The longest winning streak lasted 7 consecutive months, and the longest losing streak was 8 months.
On a daily basis, APLT closed higher 44% of trading days. The best single day was Sep 26, 2025 with a return of +121.4%, while the worst single day was Nov 29, 2024 at -76.3%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | 2.80% | 0.19% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 3.00% | |||||
| 2025 | -31.50% | -13.32% | -3.84% | -16.30% | -13.66% | -11.94% | 44.65% | 9.49% | 22.77% | 90.11% | -77.39% | -61.54% | -88.32% |
| 2024 | -6.57% | 127.48% | -4.49% | -35.00% | -3.17% | 9.11% | 27.19% | 6.73% | 34.07% | 4.00% | -77.04% | -57.82% | -74.44% |
| 2023 | 46.05% | -9.01% | -19.69% | 109.59% | -24.12% | -0.78% | 39.06% | -25.28% | 87.22% | -3.61% | -12.08% | 58.77% | 340.79% |
| 2022 | -65.59% | -38.96% | 12.23% | -6.64% | -26.90% | -34.15% | 13.90% | 26.85% | -32.11% | -16.78% | 44.70% | -32.14% | -91.51% |
| 2021 | -4.86% | 3.72% | -13.65% | -1.25% | 3.83% | 8.06% | -17.18% | -8.72% | 5.67% | -11.63% | -21.75% | -22.04% | -59.34% |
Benchmark Metrics
Applied Therapeutics, Inc. has an annualized alpha of -1.96%, beta of 1.20, and R2 of 0.04 versus S&P 500 Index. Calculated based on daily prices since May 14, 2019.
- This stock participated in 232.75% of S&P 500 Index downside but only 25.36% of its upside - more exposed to losses than it benefited from rallies.
- R2 of 0.04 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- -1.96%
- Beta
- 1.20
- R²
- 0.04
- Upside Capture
- 25.36%
- Downside Capture
- 232.75%
Return for Risk
Risk / Return Rank
APLT ranks 27 for risk / return — above 27% of stocks peers on PortfoliosLab. Its historical combined result is below the peer median.
Risk / Return Metrics
The table below present risk-adjusted performance metrics for Applied Therapeutics, Inc. (APLT) and compare them to S&P 500 Index.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| APLT | Benchmark | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.85 | ||
| Sortino ratioReturn per unit of downside risk | -1.85 | ||
| Omega ratioGain probability vs. loss probability | 1.03 | 1.25 | -0.22 |
| Calmar ratioReturn relative to maximum drawdown | -0.83 | 2.00 | -2.83 |
| Martin ratioReturn relative to average drawdown | -1.00 | 8.49 | -9.49 |
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the Applied Therapeutics, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the Applied Therapeutics, Inc. was 99.83%, occurring on Jan 27, 2026. The portfolio has not yet recovered.
The current Applied Therapeutics, Inc. drawdown is 99.81%.
Drawdown | Fall | Recovery | Underwater | Related event |
|---|---|---|---|---|
-99.83%Jan 2026 | 5y 11mo | — | 6y 5moFeb 2020 - now | — |
-19.60%Jul 2019 | 1mo 17d | 1mo 20d | 3mo 7dMay 2019 - Aug 2019 | — |
-18.10%Nov 2019 | 16d | 15d | 1mo 1dOct 2019 - Nov 2019 | — |
-14.07%Sep 2019 | 10d | 17d | 27dSep 2019 - Sep 2019 | — |
-12.83%Dec 2019 | 1d | 14d | 15dDec 2019 - Dec 2019 | — |
Drawdown Indicators
| APLT | Benchmark | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -99.83% | -56.78% | -43.05% |
Max Drawdown (1Y)Largest decline over 1 year | -93.71% | -9.10% | -84.61% |
Max Drawdown (3Y)Largest decline over 3 years | -99.10% | -18.90% | -80.20% |
Max Drawdown (5Y)Largest decline over 5 years | -99.50% | -25.43% | -74.07% |
Max Drawdown (10Y)Largest decline over 10 years | — | -33.92% | — |
Current DrawdownCurrent decline from peak | -99.81% | -1.58% | -98.23% |
Average DrawdownAverage peak-to-trough decline | -76.64% | -10.70% | -65.94% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 77.10% | 2.14% | +74.96% |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of Applied Therapeutics, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how Applied Therapeutics, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PS Ratio
This chart shows the Price-to-Sales (P/S) ratio for APLT relative to other companies in the Biotechnology industry. Currently, APLT has a P/S ratio of 15.0. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.
Income Statement
| TTM | |
|---|---|
Revenue | |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |
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