APLT vs. MRUS

Last updated Jun 4, 2026

APLT (Applied Therapeutics, Inc.) and MRUS (Merus N.V.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. At a 0.19 correlation, their price movements are largely independent.

Performance

APLT vs. MRUS - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Applied Therapeutics, Inc. (APLT) and Merus N.V. (MRUS). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

APLT

• 1D: 0.00%
• 1M: 0.00%
• YTD: 3.00%
• 6M: -51.23%
• 1Y: -71.07%
• 3Y*: -57.59%
• 5Y*: -64.97%
• 10Y*: —

MRUS

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

APLT vs. MRUS - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
APLT Applied Therapeutics, Inc.	3.00%	-88.32%	-74.44%	340.79%	-91.51%	-59.34%	-19.32%	190.21%
MRUS Merus N.V.	0.00%	114.03%	52.91%	77.76%	-51.35%	81.40%	24.50%	1.37%

Correlation

The correlation between APLT and MRUS is 0.13, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.13
Correlation (3Y) Calculated over the trailing 3-year period	0.18
Correlation (5Y) Calculated over the trailing 5-year period	0.21
Correlation (All Time) Calculated using the full available price history since May 15, 2019	0.19

Fundamentals

Market Cap APLT : $14.99M MRUS : $6.81B
EPS APLT : -$0.12 MRUS : -$4.56
PS Ratio APLT : 14.97 MRUS : 129.06
Total Revenue (TTM) APLT : $1.00M MRUS : $51.17M
Gross Profit (TTM) APLT : -$28.46M MRUS : -$111.30M
EBITDA (TTM) APLT : -$100.52M MRUS : -$323.66M

Return for Risk

APLT vs. MRUS — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

APLT

APLT Risk / Return Rank: 28
APLT Sharpe Ratio Rank: 24
APLT Sortino Ratio Rank: 40
APLT Omega Ratio Rank: 46
APLT Calmar Ratio Rank: 12
APLT Martin Ratio Rank: 19

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

APLT vs. MRUS - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Applied Therapeutics, Inc. (APLT) and Merus N.V. (MRUS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	APLT	MRUS	Difference
Sharpe ratio Return per unit of total volatility	-0.39	—	—
Sortino ratio Return per unit of downside risk	0.41	—	—
Omega ratio Gain probability vs. loss probability	1.09	—	—
Calmar ratio Return relative to maximum drawdown	-0.77	—	—
Martin ratio Return relative to average drawdown	-1.05	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	APLT	MRUS	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.39	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.49	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.39	—	—

Drawdowns

Drawdown Indicators

	APLT	MRUS	Difference
Max Drawdown Largest peak-to-trough decline	-99.83%	—	—
Max Drawdown (1Y) Largest decline over 1 year	-93.71%	—	—
Max Drawdown (3Y) Largest decline over 3 years	-99.10%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-99.63%	—	—
Current Drawdown Current decline from peak	-99.81%	—	—
Average Drawdown Average peak-to-trough decline	-76.16%	—	—
Ulcer Index Depth and duration of drawdowns from previous peaks	67.82%	—	—

Volatility

Volatility by Period

	APLT	MRUS	Difference
Volatility (1M) Calculated over the trailing 1-month period	0.00%	—	—
Volatility (6M) Calculated over the trailing 6-month period	70.36%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	182.93%	—	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	132.93%	—	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	122.33%	—	—

Dividends

APLT vs. MRUS - Dividend Comparison

Neither APLT nor MRUS has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both APLT and MRUS in my portfolio?

APLT and MRUS have a correlation of 0.13, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.