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ISIN
US03589W1027
CUSIP
03589W102
IPO Date
Jul 24, 2020

Highlights

Market Cap
$1.03B
Enterprise Value
$878.62M
EPS (TTM)
-$1.22
Gross Profit (TTM)
-$1.90M
EBITDA (TTM)
-$199.90M
Year Range
$1.85 - $7.18
Target Price
$11.50
ROA (TTM)
-74.74%
ROE (TTM)
-96.06%

Share Price Chart


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Annexon, Inc.

Often compared with ANNX:
ANNX vs. CRT

Performance

ANNX Performance Chart

Annexon, Inc. (ANNX) is up 5.2% since the beginning of the year. At $5 per share, ANNX is trading 26.5% below its 52-week high of $7. Investors who bought $1,000 worth of ANNX shares 5 years ago would now be looking at an investment worth $223.


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S&P 500 Index

Returns By Period

Annexon, Inc. (ANNX) has returned 5.18% so far this year and 121.85% over the past 12 months.


Annexon, Inc.

1D
4.76%
1M
-0.56%
YTD
5.18%
6M
3.33%
1Y
121.85%
3Y*
14.91%
5Y*
-25.91%
10Y*

Benchmark (S&P 500 Index)

1D
-1.44%
1M
-1.45%
YTD
7.60%
6M
6.59%
1Y
22.24%
3Y*
19.20%
5Y*
11.54%
10Y*
13.71%
*Multi-year figures are annualized to reflect compound growth (CAGR)

ANNX Monthly Returns History

Based on dividend-adjusted daily data since Jul 24, 2020, ANNX's average daily return is +0.08%, while the average monthly return is +1.24%. At this rate, an investment would double in approximately 4.7 years.

Historically, 49% of months were positive and 51% were negative. The best month was Dec 2023 with a return of +82.3%, while the worst month was Mar 2022 at -43.8%. The longest winning streak lasted 5 consecutive months, and the longest losing streak was 7 months.

On a daily basis, ANNX closed higher 47% of trading days. The best single day was May 26, 2023 with a return of +35.7%, while the worst single day was May 25, 2023 at -59.4%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
202624.30%-10.26%-1.07%5.96%-7.67%-2.58%5.18%
2025-25.15%-31.25%-26.89%-3.63%9.68%17.65%0.00%-14.17%48.06%3.61%42.41%11.56%-2.14%
2024-8.48%34.06%28.73%-36.54%6.15%1.45%30.82%-11.08%3.86%23.65%-26.37%-4.82%13.00%
202338.10%-25.35%-27.77%37.79%-43.64%17.73%-1.99%-20.29%-14.18%-3.81%9.69%82.33%-12.19%
2022-34.73%-35.27%-43.77%-6.59%23.14%20.06%32.89%17.37%5.10%-22.65%13.81%-4.96%-55.00%
2021-12.11%32.32%-4.36%-28.41%5.97%6.58%-6.44%-22.36%13.82%-12.36%-0.12%-29.47%-54.10%

Benchmark Metrics

Annexon, Inc. has an annualized alpha of 2.59%, beta of 1.10, and R2 of 0.04 versus S&P 500 Index. Calculated based on daily prices since July 24, 2020.

  • This stock participated in 190.60% of S&P 500 Index downside but only 69.56% of its upside - more exposed to losses than it benefited from rallies.
  • R2 of 0.04 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
2.59%
Beta
1.10
0.04
Upside Capture
69.56%
Downside Capture
190.60%

Return for Risk

Risk / Return Rank

ANNX ranks 83 for risk / return — in the top 83% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.


ANNX Risk / Return Rank: 8383
Overall Rank
ANNX Sharpe Ratio Rank: 8383
Sharpe Ratio Rank
ANNX Sortino Ratio Rank: 8484
Sortino Ratio Rank
ANNX Omega Ratio Rank: 7878
Omega Ratio Rank
ANNX Calmar Ratio Rank: 8787
Calmar Ratio Rank
ANNX Martin Ratio Rank: 8383
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Annexon, Inc. (ANNX) and compare them to S&P 500 Index.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


ANNXBenchmarkDifference
Sharpe ratioReturn per unit of total volatility

-0.20

Sortino ratioReturn per unit of downside risk

+0.05

Omega ratioGain probability vs. loss probability

1.27

1.32

-0.05

Calmar ratioReturn relative to maximum drawdown

3.50

2.46

+1.04

Martin ratioReturn relative to average drawdown

7.24

10.92

-3.68

Dividends

Dividend History


Annexon, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Annexon, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Annexon, Inc. was 96.06%, occurring on Apr 10, 2025. The portfolio has not yet recovered.

The current Annexon, Inc. drawdown is 84.92%.


Related event

Drawdown

Fall

Recovery

Underwater

2025 selloff2025
-96.06%Apr 2025
4y 25d
5y 3moMar 2021 - now
2020 bear market2020
-31.37%Oct 2020
11d1mo 24d
2mo 5dOct 2020 - Dec 2020
2021 bear market2021
-27.99%Jan 2021
1mo 6d24d
2moDec 2020 - Feb 2021
2020 bear market2020
-25.64%Sep 2020
1mo 5d13d
1mo 18dAug 2020 - Sep 2020
2021 correction2021
-13.04%Mar 2021
13d3d
16dFeb 2021 - Mar 2021

Drawdown Indicators


ANNXBenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-96.06%

-56.78%

-39.28%

Max Drawdown (1Y)

Largest decline over 1 year

-35.06%

-9.10%

-25.96%

Max Drawdown (3Y)

Largest decline over 3 years

-82.33%

-18.90%

-63.43%

Max Drawdown (5Y)

Largest decline over 5 years

-94.24%

-25.43%

-68.81%

Max Drawdown (10Y)

Largest decline over 10 years

-33.92%

Current Drawdown

Current decline from peak

-84.92%

-3.21%

-81.71%

Average Drawdown

Average peak-to-trough decline

-73.09%

-10.71%

-62.38%

Ulcer Index

Depth and duration of drawdowns from previous peaks

16.91%

2.04%

+14.87%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Annexon, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Annexon, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for ANNX in comparison with other companies in the Biotechnology industry. Currently, ANNX has a P/B value of 5.0. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
Portfolio Analyzer

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