ANNX vs. CRT

Last updated Jul 14, 2026

ANNX (Annexon, Inc.) and CRT (Cross Timbers Royalty Trust) are both stocks. ANNX operates in Biotechnology (Healthcare), while CRT operates in Oil & Gas E&P (Energy). Over the past 5 years, ANNX returned -24.17%/yr vs 4.68%/yr for CRT. At a 0.06 correlation, their price movements are largely independent.

Performance

ANNX vs. CRT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Annexon, Inc. (ANNX) and Cross Timbers Royalty Trust (CRT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ANNX achieves a 12.15% return, which is significantly lower than CRT's 19.13% return.

ANNX

• 1D: -2.93%
• 1M: 19.53%
• 6M: 1.26%
• YTD: 12.15%
• 1Y: 118.22%
• 3Y*: 15.23%
• 5Y*: -24.17%
• 10Y*: —

CRT

• 1D: 0.49%
• 1M: -13.85%
• 6M: 15.36%
• YTD: 19.13%
• 1Y: 1.18%
• 3Y*: -16.29%
• 5Y*: 4.68%
• 10Y*: 0.90%

*Multi-year figures are annualized to reflect compound growth (CAGR)

ANNX vs. CRT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
ANNX Annexon, Inc.	12.15%	-2.14%	13.00%	-12.19%	-55.00%	-54.10%	43.85%
CRT Cross Timbers Royalty Trust	19.13%	-13.15%	-39.15%	-24.36%	145.90%	53.31%	30.15%

Correlation

The correlation between ANNX and CRT is 0.02, meaning there is essentially no relationship between their price movements. Each responds to its own set of market drivers, making them strong candidates for combining in a diversified portfolio.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.02
Correlation (3Y) Calculated over the trailing 3-year period	0.04
Correlation (5Y) Calculated over the trailing 5-year period	0.07
Correlation (All Time) Calculated using the full available price history since Jul 24, 2020	0.06

Fundamentals

Market Cap ANNX : $673.32M CRT : $55.50M
EPS ANNX : -$1.18 CRT : $0.54
PB Ratio ANNX : 5.35 CRT : 26.12
Total Revenue (TTM) ANNX : $0.00 CRT : $4.50M
Gross Profit (TTM) ANNX : -$1.90M CRT : $4.33M
EBITDA (TTM) ANNX : -$199.90M CRT : $3.36M

Return for Risk

ANNX vs. CRT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ANNX

ANNX Risk / Return Rank: 85
ANNX Sharpe Ratio Rank: 86
ANNX Sortino Ratio Rank: 86
ANNX Omega Ratio Rank: 81
ANNX Calmar Ratio Rank: 89
ANNX Martin Ratio Rank: 86

CRT

CRT Risk / Return Rank: 44
CRT Sharpe Ratio Rank: 47
CRT Sortino Ratio Rank: 41
CRT Omega Ratio Rank: 41
CRT Calmar Ratio Rank: 46
CRT Martin Ratio Rank: 47

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ANNX vs. CRT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Annexon, Inc. (ANNX) and Cross Timbers Royalty Trust (CRT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	ANNX	CRT	Difference
Sharpe ratio: Return per unit of total volatility	1.54	0.04	+1.50
Sortino ratio: Return per unit of downside risk	2.45	0.29	+2.16
Omega ratio: Gain probability vs. loss probability	1.27	1.04	+0.23
Calmar ratio: Return relative to maximum drawdown	3.39	0.04	+3.35
Martin ratio: Return relative to average drawdown	7.39	0.09	+7.29

ANNX vs. CRT - Sharpe Ratio Comparison

The current ANNX Sharpe Ratio is 1.54, which is higher than the CRT Sharpe Ratio of 0.04. The chart below compares the historical Sharpe Ratios of ANNX and CRT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

ANNX vs. CRT - Drawdown Comparison

The maximum ANNX drawdown since its inception was -96.06%, which is greater than CRT's maximum drawdown of -83.57%. Use the drawdown chart below to compare losses from any high point for ANNX and CRT.

Drawdown Indicators

	ANNX	CRT	Difference
Max Drawdown Largest peak-to-trough decline	-96.06%	-83.57%	-12.49%
Max Drawdown (1Y) Largest decline over 1 year	-35.06%	-27.18%	-7.88%
Max Drawdown (3Y) Largest decline over 3 years	-82.33%	-63.52%	-18.81%
Max Drawdown (5Y) Largest decline over 5 years	-94.08%	-71.10%	-22.98%
Max Drawdown (10Y) Largest decline over 10 years	—	-71.10%	—
Current Drawdown Current decline from peak	-83.92%	-60.22%	-23.70%
Average Drawdown Average peak-to-trough decline	-73.19%	-29.48%	-43.71%
Ulcer Index Depth and duration of drawdowns from previous peaks	16.06%	12.85%	+3.21%

Volatility

ANNX vs. CRT - Volatility Comparison

Annexon, Inc. (ANNX) has a higher volatility of 19.89% compared to Cross Timbers Royalty Trust (CRT) at 11.48%. This indicates that ANNX's price experiences larger fluctuations and is considered to be riskier than CRT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ANNX	CRT	Difference
Volatility (1M) Calculated over the trailing 1-month period	19.89%	11.48%	+8.41%
Volatility (6M) Calculated over the trailing 6-month period	48.64%	21.59%	+27.05%
Volatility (1Y) Calculated over the trailing 1-year period	77.59%	32.16%	+45.43%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	89.84%	50.40%	+39.44%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	87.33%	46.06%	+41.27%

Dividends

ANNX vs. CRT - Dividend Comparison

ANNX has not paid dividends to shareholders, while CRT's dividend yield for the trailing twelve months is around 5.73%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
ANNX Annexon, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
CRT Cross Timbers Royalty Trust	5.73%	9.41%	9.56%	10.96%	7.69%	9.71%	9.45%	10.04%	13.06%	6.87%	5.90%	10.41%

Financials

Frequently Asked Questions

Can I hold both ANNX and CRT in my portfolio?

ANNX and CRT have a correlation of 0.02, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ANNX or CRT?

ANNX has higher volatility (19.89%) compared to CRT (11.48%). In terms of maximum drawdown, ANNX dropped -96.06% vs CRT's -83.57%.

Which has better risk-adjusted returns?

ANNX currently has the higher Sharpe Ratio (1.54 vs 0.04), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.