VERX vs. CRSP

Last updated Apr 2, 2026

Compare and contrast key facts about Vertex, Inc. (VERX) and CRISPR Therapeutics AG (CRSP).

Performance

VERX vs. CRSP - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Vertex, Inc. (VERX) and CRISPR Therapeutics AG (CRSP). The values are adjusted to include any dividend payments, if applicable.

VERX vs. CRSP - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
VERX Vertex, Inc.	-39.46%	-62.57%	98.03%	85.67%	-8.57%	-54.46%	45.63%
CRSP CRISPR Therapeutics AG	-6.92%	33.23%	-37.12%	54.00%	-46.36%	-50.51%	79.01%

Fundamentals

EPS VERX : $0.07 CRSP : -$5.47
PS Ratio VERX : 1.73 CRSP : 118.44
Total Revenue (TTM) VERX : $748.44M CRSP : $36.75M
Gross Profit (TTM) VERX : $481.60M CRSP : -$130.60M
EBITDA (TTM) VERX : $46.96M CRSP : -$529.50M

Returns By Period

In the year-to-date period, VERX achieves a -39.46% return, which is significantly lower than CRSP's -6.92% return.

VERX

• 1D: 1.68%
• 1M: -16.04%
• YTD: -39.46%
• 6M: -50.73%
• 1Y: -66.49%
• 3Y*: -16.40%
• 5Y*: -12.21%
• 10Y*: —

CRSP

• 1D: 2.61%
• 1M: -19.68%
• YTD: -6.92%
• 6M: -26.22%
• 1Y: 47.28%
• 3Y*: 2.57%
• 5Y*: -16.38%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

VERX vs. CRSP — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

VERX

VERX Risk / Return Rank: 4
VERX Sharpe Ratio Rank: 1
VERX Sortino Ratio Rank: 1
VERX Omega Ratio Rank: 2
VERX Calmar Ratio Rank: 7
VERX Martin Ratio Rank: 9

CRSP

CRSP Risk / Return Rank: 64
CRSP Sharpe Ratio Rank: 66
CRSP Sortino Ratio Rank: 67
CRSP Omega Ratio Rank: 62
CRSP Calmar Ratio Rank: 63
CRSP Martin Ratio Rank: 60

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

VERX vs. CRSP - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Vertex, Inc. (VERX) and CRISPR Therapeutics AG (CRSP). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	VERX	CRSP	Difference
Sharpe ratio Return per unit of total volatility	-1.30	0.75	-2.05
Sortino ratio Return per unit of downside risk	-2.32	1.50	-3.82
Omega ratio Gain probability vs. loss probability	0.71	1.17	-0.47
Calmar ratio Return relative to maximum drawdown	-0.90	1.03	-1.93
Martin ratio Return relative to average drawdown	-1.51	2.03	-3.55
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

VERX vs. CRSP - Sharpe Ratio Comparison

The current VERX Sharpe Ratio is -1.30, which is lower than the CRSP Sharpe Ratio of 0.75. The chart below compares the historical Sharpe Ratios of VERX and CRSP, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	VERX	CRSP	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-1.30	0.75	-2.05
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.23	-0.27	+0.04
Sharpe Ratio (All Time) Calculated using the full available price history	-0.21	0.22	-0.43

Correlation

The correlation between VERX and CRSP is 0.30, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

VERX vs. CRSP - Dividend Comparison

Neither VERX nor CRSP has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

VERX vs. CRSP - Drawdown Comparison

The maximum VERX drawdown since its inception was -80.76%, smaller than the maximum CRSP drawdown of -85.11%. Use the drawdown chart below to compare losses from any high point for VERX and CRSP.

Drawdown Indicators

	VERX	CRSP	Difference
Max Drawdown Largest peak-to-trough decline	-80.76%	-85.11%	+4.35%
Max Drawdown (1Y) Largest decline over 1 year	-72.92%	-42.25%	-30.67%
Max Drawdown (5Y) Largest decline over 5 years	-80.76%	-80.68%	-0.08%
Current Drawdown Current decline from peak	-79.49%	-76.76%	-2.73%
Average Drawdown Average peak-to-trough decline	-41.15%	-48.71%	+7.56%
Ulcer Index Depth and duration of drawdowns from previous peaks	43.34%	21.35%	+21.99%

Volatility

VERX vs. CRSP - Volatility Comparison

The current volatility for Vertex, Inc. (VERX) is 13.23%, while CRISPR Therapeutics AG (CRSP) has a volatility of 18.14%. This indicates that VERX experiences smaller price fluctuations and is considered to be less risky than CRSP based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	VERX	CRSP	Difference
Volatility (1M) Calculated over the trailing 1-month period	13.23%	18.14%	-4.91%
Volatility (6M) Calculated over the trailing 6-month period	39.40%	44.91%	-5.51%
Volatility (1Y) Calculated over the trailing 1-year period	51.25%	63.81%	-12.56%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	53.82%	60.36%	-6.54%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	54.87%	64.42%	-9.55%

Financials