TECH vs. PFE

Last updated Apr 1, 2026

Compare and contrast key facts about Bio-Techne Corporation (TECH) and Pfizer Inc. (PFE).

Performance

TECH vs. PFE - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Bio-Techne Corporation (TECH) and Pfizer Inc. (PFE). The values are adjusted to include any dividend payments, if applicable.

TECH vs. PFE - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
TECH Bio-Techne Corporation	-11.02%	-17.89%	-6.13%	-6.49%	-35.69%	63.40%	45.40%	52.67%	12.60%	27.40%
PFE Pfizer Inc.	14.66%	0.65%	-2.22%	-41.26%	-10.41%	66.70%	3.07%	-6.91%	24.82%	15.90%

Fundamentals

Market Cap TECH : $8.19B PFE : $159.66B
EPS TECH : $0.52 PFE : $1.36
PE Ratio TECH : 100.53 PFE : 20.61
PS Ratio TECH : 6.71 PFE : 2.56
PB Ratio TECH : 4.03 PFE : 1.72
Total Revenue (TTM) TECH : $1.22B PFE : $62.58B
Gross Profit (TTM) TECH : $792.76M PFE : $44.01B
EBITDA (TTM) TECH : $173.06M PFE : $15.10B

Returns By Period

In the year-to-date period, TECH achieves a -11.02% return, which is significantly lower than PFE's 14.66% return. Over the past 10 years, TECH has outperformed PFE with an annualized return of 8.84%, while PFE has yielded a comparatively lower 4.32% annualized return.

TECH

• 1D: 0.42%
• 1M: -11.42%
• YTD: -11.02%
• 6M: -5.80%
• 1Y: -10.34%
• 3Y*: -10.55%
• 5Y*: -11.26%
• 10Y*: 8.84%

PFE

• 1D: 1.12%
• 1M: 1.56%
• YTD: 14.66%
• 6M: 14.02%
• 1Y: 18.86%
• 3Y*: -6.22%
• 5Y*: -0.14%
• 10Y*: 4.32%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

TECH vs. PFE — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TECH

TECH Risk / Return Rank: 30
TECH Sharpe Ratio Rank: 31
TECH Sortino Ratio Rank: 29
TECH Omega Ratio Rank: 29
TECH Calmar Ratio Rank: 32
TECH Martin Ratio Rank: 29

PFE

PFE Risk / Return Rank: 65
PFE Sharpe Ratio Rank: 67
PFE Sortino Ratio Rank: 61
PFE Omega Ratio Rank: 59
PFE Calmar Ratio Rank: 69
PFE Martin Ratio Rank: 69

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TECH vs. PFE - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Bio-Techne Corporation (TECH) and Pfizer Inc. (PFE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	TECH	PFE	Difference
Sharpe ratio Return per unit of total volatility	-0.23	0.71	-0.94
Sortino ratio Return per unit of downside risk	-0.04	1.17	-1.21
Omega ratio Gain probability vs. loss probability	1.00	1.15	-0.15
Calmar ratio Return relative to maximum drawdown	-0.33	1.32	-1.65
Martin ratio Return relative to average drawdown	-0.81	3.18	-3.98
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

TECH vs. PFE - Sharpe Ratio Comparison

The current TECH Sharpe Ratio is -0.23, which is lower than the PFE Sharpe Ratio of 0.71. The chart below compares the historical Sharpe Ratios of TECH and PFE, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	TECH	PFE	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.23	0.71	-0.94
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.31	-0.01	-0.30
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.27	0.18	+0.09
Sharpe Ratio (All Time) Calculated using the full available price history	0.34	0.26	+0.07

Correlation

The correlation between TECH and PFE is 0.34, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

TECH vs. PFE - Dividend Comparison

TECH's dividend yield for the trailing twelve months is around 0.61%, less than PFE's 6.13% yield.

	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
TECH Bio-Techne Corporation	0.61%	0.54%	0.56%	0.41%	0.39%	0.25%	0.40%	0.58%	0.88%	0.99%	1.24%	1.42%
PFE Pfizer Inc.	6.13%	6.91%	6.33%	5.70%	3.12%	2.64%	3.92%	3.68%	3.12%	3.53%	3.69%	3.47%

Drawdowns

TECH vs. PFE - Drawdown Comparison

The maximum TECH drawdown since its inception was -74.39%, which is greater than PFE's maximum drawdown of -58.96%. Use the drawdown chart below to compare losses from any high point for TECH and PFE.

Drawdown Indicators

	TECH	PFE	Difference
Max Drawdown Largest peak-to-trough decline	-74.39%	-58.96%	-15.43%
Max Drawdown (1Y) Largest decline over 1 year	-31.52%	-12.59%	-18.93%
Max Drawdown (5Y) Largest decline over 5 years	-64.78%	-58.96%	-5.82%
Max Drawdown (10Y) Largest decline over 10 years	-64.78%	-58.96%	-5.82%
Current Drawdown Current decline from peak	-60.38%	-42.75%	-17.63%
Average Drawdown Average peak-to-trough decline	-23.92%	-17.33%	-6.59%
Ulcer Index Depth and duration of drawdowns from previous peaks	13.03%	6.13%	+6.90%

Volatility

TECH vs. PFE - Volatility Comparison

Bio-Techne Corporation (TECH) has a higher volatility of 11.25% compared to Pfizer Inc. (PFE) at 6.75%. This indicates that TECH's price experiences larger fluctuations and is considered to be riskier than PFE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	TECH	PFE	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.25%	6.75%	+4.50%
Volatility (6M) Calculated over the trailing 6-month period	27.94%	18.50%	+9.44%
Volatility (1Y) Calculated over the trailing 1-year period	44.26%	26.73%	+17.53%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	37.04%	25.46%	+11.58%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	32.95%	23.90%	+9.05%

Financials

TECH vs. PFE - Profitability Comparison

The chart below illustrates the profitability comparison between Bio-Techne Corporation and Pfizer Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

TECH - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Bio-Techne Corporation reported a gross profit of 189.20M and revenue of 295.88M. Therefore, the gross margin over that period was 63.9%.

PFE - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Pfizer Inc. reported a gross profit of 12.29B and revenue of 17.56B. Therefore, the gross margin over that period was 70.0%.

TECH - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Bio-Techne Corporation reported an operating income of 54.46M and revenue of 295.88M, resulting in an operating margin of 18.4%.

PFE - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Pfizer Inc. reported an operating income of 3.69B and revenue of 17.56B, resulting in an operating margin of 21.0%.

TECH - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Bio-Techne Corporation reported a net income of 38.02M and revenue of 295.88M, resulting in a net margin of 12.9%.

PFE - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Pfizer Inc. reported a net income of -1.65B and revenue of 17.56B, resulting in a net margin of -9.4%.