SPRY vs. MIST
SPRY (Silverback Therapeutics Inc) and MIST (Milestone Pharmaceuticals Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 5 years, SPRY returned -28.53%/yr vs -27.37%/yr for MIST. Their 0.20 correlation means their historical movements had little consistent relationship.
Performance
SPRY vs. MIST - Performance Comparison
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Returns By Period
In the year-to-date period, SPRY achieves a -53.13% return, which is significantly lower than MIST's -44.55% return.
SPRY
- 1D
- 6.43%
- 1M
- -36.21%
- 6M
- -46.99%
- YTD
- -53.13%
- 1Y
- -68.22%
- 3Y*
- -8.08%
- 5Y*
- -28.53%
- 10Y*
- —
- ALL TIME*
- -25.54%
MIST
- 1D
- 0.90%
- 1M
- -15.15%
- 6M
- -42.86%
- YTD
- -44.55%
- 1Y
- -21.68%
- 3Y*
- -28.23%
- 5Y*
- -27.37%
- 10Y*
- —
- ALL TIME*
- -30.52%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $1.43M | $1.38M | $1.89M | |
| $17.38M | $14.89M | $16.09M |
SPRY vs. MIST - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|---|
SPRY Silverback Therapeutics Inc | -53.13% | 10.43% | 92.52% | -35.76% | 28.08% | -85.63% | 59.79% |
MIST Milestone Pharmaceuticals Inc. | -44.55% | -14.41% | 41.32% | -57.83% | -39.54% | -2.24% | -0.00% |
Correlation
The correlation between SPRY and MIST is 0.26, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.26 |
Correlation (3Y) Balances recent behavior with more history. | 0.22 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.19 |
Correlation (All Time) Calculated using the full available price history since Dec 4, 2020 | 0.20 |
Fundamentals
SPRY:
$542.20M
MIST:
$96.20M
SPRY:
-$2.00
MIST:
-$0.45
SPRY:
5.45
MIST:
58.71
SPRY:
8.84
MIST:
4.05
SPRY:
$98.99M
MIST:
$1.78M
SPRY:
$59.93M
MIST:
$1.75M
SPRY:
-$194.60M
MIST:
-$63.04M
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Return for Risk
SPRY vs. MIST — Risk / Return Rank
SPRY
MIST
SPRY vs. MIST - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Silverback Therapeutics Inc (SPRY) and Milestone Pharmaceuticals Inc. (MIST). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| SPRY | MIST | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.64 | ||
| Sortino ratioReturn per unit of downside risk | -1.67 | ||
| Omega ratioGain probability vs. loss probability | 0.81 | 1.00 | -0.19 |
| Calmar ratioReturn relative to maximum drawdown | -0.96 | -0.33 | -0.63 |
| Martin ratioReturn relative to average drawdown | -1.42 | -0.59 | -0.83 |
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Drawdowns
SPRY vs. MIST - Drawdown Comparison
The maximum SPRY drawdown since its inception was -95.20%, roughly equal to the maximum MIST drawdown of -97.60%. Use the drawdown chart below to compare losses from any high point for SPRY and MIST.
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Drawdown Indicators
| SPRY | MIST | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -95.20% | -97.60% | +2.40% |
Max Drawdown (1Y)Largest decline over 1 year | -71.47% | -65.76% | -5.71% |
Max Drawdown (3Y)Largest decline over 3 years | -72.04% | -81.18% | +9.14% |
Max Drawdown (5Y)Largest decline over 5 years | -90.62% | -93.13% | +2.51% |
Current DrawdownCurrent decline from peak | -90.96% | -95.87% | +4.91% |
Average DrawdownAverage peak-to-trough decline | -78.45% | -78.61% | +0.16% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 47.94% | 36.62% | +11.32% |
Volatility
SPRY vs. MIST - Volatility Comparison
The current volatility for Silverback Therapeutics Inc (SPRY) is 15.51%, while Milestone Pharmaceuticals Inc. (MIST) has a volatility of 18.14%. This indicates that SPRY experiences smaller price fluctuations and is considered to be less risky than MIST based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| SPRY | MIST | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 15.51% | 18.14% | -2.63% |
Volatility (6M)Calculated over the trailing 6-month period | 49.67% | 55.16% | -5.49% |
Volatility (1Y)Calculated over the trailing 1-year period | 71.94% | 70.65% | +1.29% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 80.63% | 78.01% | +2.62% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 81.14% | 104.44% | -23.30% |
Dividends
SPRY vs. MIST - Dividend Comparison
Neither SPRY nor MIST has paid dividends to shareholders.
Financials
SPRY vs. MIST - Financials Comparison
This section allows you to compare key financial metrics between Silverback Therapeutics Inc and Milestone Pharmaceuticals Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
SPRY and MIST have a correlation of 0.26, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
MIST has higher volatility (18.14%) compared to SPRY (15.51%). In terms of maximum drawdown, SPRY dropped -95.20% vs MIST's -97.60%.
MIST currently has the higher Sharpe Ratio (-0.31 vs -0.95), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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