SPRO vs. SPRX
SPRO (Spero Therapeutics, Inc.) is a stock, while SPRX (Spear Alpha ETF) is Technology Equities fund actively managed by Spear. Over the past 3 years, SPRO returned 4.03%/yr vs 36.79%/yr for SPRX. At a 0.27 correlation, their price movements are largely independent.
Performance
SPRO vs. SPRX - Performance Comparison
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Returns By Period
In the year-to-date period, SPRO achieves a -27.04% return, which is significantly lower than SPRX's 26.39% return.
SPRO
- 1D
- -22.02%
- 1M
- -40.35%
- 6M
- -30.61%
- YTD
- -27.04%
- 1Y
- -35.61%
- 3Y*
- 4.03%
- 5Y*
- -34.67%
- 10Y*
- —
SPRX
- 1D
- 0.96%
- 1M
- -12.04%
- 6M
- 15.88%
- YTD
- 26.39%
- 1Y
- 64.27%
- 3Y*
- 36.79%
- 5Y*
- —
- 10Y*
- —
SPRO vs. SPRX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
SPRO Spero Therapeutics, Inc. | -27.04% | 126.21% | -29.93% | -15.03% | -89.19% | 15.43% |
SPRX Spear Alpha ETF | 26.39% | 41.91% | 20.58% | 88.02% | -44.99% | 9.15% |
Correlation
The correlation between SPRO and SPRX is 0.26, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.26 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.23 |
Correlation (All Time) Calculated using the full available price history since Aug 4, 2021 | 0.27 |
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Return for Risk
SPRO vs. SPRX — Risk / Return Rank
SPRO
SPRX
SPRO vs. SPRX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Spero Therapeutics, Inc. (SPRO) and Spear Alpha ETF (SPRX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| SPRO | SPRX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.88 | ||
| Sortino ratioReturn per unit of downside risk | -2.28 | ||
| Omega ratioGain probability vs. loss probability | 0.93 | 1.23 | -0.30 |
| Calmar ratioReturn relative to maximum drawdown | -0.83 | 2.67 | -3.50 |
| Martin ratioReturn relative to average drawdown | -2.50 | 7.74 | -10.24 |
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Drawdowns
SPRO vs. SPRX - Drawdown Comparison
The maximum SPRO drawdown since its inception was -97.46%, which is greater than SPRX's maximum drawdown of -51.21%. Use the drawdown chart below to compare losses from any high point for SPRO and SPRX.
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Drawdown Indicators
| SPRO | SPRX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.46% | -51.21% | -46.25% |
Max Drawdown (1Y)Largest decline over 1 year | -42.95% | -24.21% | -18.74% |
Max Drawdown (3Y)Largest decline over 3 years | -68.89% | -42.12% | -26.77% |
Max Drawdown (5Y)Largest decline over 5 years | -97.13% | — | — |
Current DrawdownCurrent decline from peak | -92.30% | -17.21% | -75.09% |
Average DrawdownAverage peak-to-trough decline | -62.61% | -17.44% | -45.17% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 15.92% | 8.33% | +7.59% |
Volatility
SPRO vs. SPRX - Volatility Comparison
Spero Therapeutics, Inc. (SPRO) has a higher volatility of 40.57% compared to Spear Alpha ETF (SPRX) at 19.18%. This indicates that SPRO's price experiences larger fluctuations and is considered to be riskier than SPRX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| SPRO | SPRX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 40.57% | 19.18% | +21.39% |
Volatility (6M)Calculated over the trailing 6-month period | 52.69% | 40.35% | +12.34% |
Volatility (1Y)Calculated over the trailing 1-year period | 63.53% | 49.00% | +14.53% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 152.30% | 42.65% | +109.65% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 124.80% | 42.65% | +82.15% |
Dividends
SPRO vs. SPRX - Dividend Comparison
Neither SPRO nor SPRX has paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
SPRO Spero Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SPRX Spear Alpha ETF | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.25% |
Frequently Asked Questions
SPRO and SPRX have a correlation of 0.26, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SPRO has higher volatility (40.57%) compared to SPRX (19.18%). In terms of maximum drawdown, SPRO dropped -97.46% vs SPRX's -51.21%.
SPRX currently has the higher Sharpe Ratio (1.32 vs -0.56), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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