SPRO vs. SPRX
SPRO (Spero Therapeutics, Inc.) is a stock, while SPRX (Spear Alpha ETF) is Technology Equities fund actively managed by Spear. Over the past 5 years, SPRO returned -39.05%/yr vs 17.38%/yr for SPRX. Their 0.26 correlation means their historical movements had little consistent relationship.
Performance
SPRO vs. SPRX - Performance Comparison
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Returns By Period
In the year-to-date period, SPRO achieves a -50.64% return, which is significantly lower than SPRX's 15.61% return.
SPRO
- 1D
- -1.71%
- 1M
- -47.73%
- 6M
- -48.43%
- YTD
- -50.64%
- 1Y
- -50.00%
- 3Y*
- -8.68%
- 5Y*
- -39.05%
- 10Y*
- —
- ALL TIME*
- -24.37%
SPRX
- 1D
- 4.53%
- 1M
- -12.28%
- 6M
- 9.85%
- YTD
- 15.61%
- 1Y
- 38.42%
- 3Y*
- 33.78%
- 5Y*
- 17.38%
- 10Y*
- —
- ALL TIME*
- 17.45%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $3.18M | $3.27M | $3.19M | |
SPRX Spear Alpha ETF | $6.76M | $5.78M | $7.67M |
SPRO vs. SPRX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | |
|---|---|---|---|---|---|---|
SPRO Spero Therapeutics, Inc. | -50.64% | 126.21% | -29.93% | -15.03% | -89.19% | 15.43% |
SPRX Spear Alpha ETF | 15.61% | 41.91% | 20.58% | 88.02% | -44.99% | 9.15% |
Correlation
The correlation between SPRO and SPRX is 0.26, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.26 |
Correlation (3Y) Balances recent behavior with more history. | 0.22 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.26 |
Correlation (All Time) Calculated using the full available price history since Aug 4, 2021 | 0.26 |
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Return for Risk
SPRO vs. SPRX — Risk / Return Rank
SPRO
SPRX
SPRO vs. SPRX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Spero Therapeutics, Inc. (SPRO) and Spear Alpha ETF (SPRX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| SPRO | SPRX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -1.52 | ||
| Sortino ratioReturn per unit of downside risk | -2.19 | ||
| Omega ratioGain probability vs. loss probability | 0.87 | 1.16 | -0.29 |
| Calmar ratioReturn relative to maximum drawdown | -0.82 | 1.08 | -1.89 |
| Martin ratioReturn relative to average drawdown | -2.68 | 3.74 | -6.42 |
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Drawdowns
SPRO vs. SPRX - Drawdown Comparison
The maximum SPRO drawdown since its inception was -97.46%, which is greater than SPRX's maximum drawdown of -51.21%. Use the drawdown chart below to compare losses from any high point for SPRO and SPRX.
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Drawdown Indicators
| SPRO | SPRX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -97.46% | -51.21% | -46.25% |
Max Drawdown (1Y)Largest decline over 1 year | -61.41% | -35.87% | -25.54% |
Max Drawdown (3Y)Largest decline over 3 years | -68.89% | -42.12% | -26.77% |
Max Drawdown (5Y)Largest decline over 5 years | -97.13% | -51.21% | -45.92% |
Current DrawdownCurrent decline from peak | -94.79% | -24.26% | -70.53% |
Average DrawdownAverage peak-to-trough decline | -62.81% | -17.53% | -45.28% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 18.67% | 10.30% | +8.37% |
Volatility
SPRO vs. SPRX - Volatility Comparison
Spero Therapeutics, Inc. (SPRO) has a higher volatility of 28.60% compared to Spear Alpha ETF (SPRX) at 21.39%. This indicates that SPRO's price experiences larger fluctuations and is considered to be riskier than SPRX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| SPRO | SPRX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 28.60% | 21.39% | +7.21% |
Volatility (6M)Calculated over the trailing 6-month period | 54.67% | 43.52% | +11.15% |
Volatility (1Y)Calculated over the trailing 1-year period | 64.65% | 52.25% | +12.40% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 152.44% | 43.25% | +109.19% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 124.55% | 43.25% | +81.30% |
Dividends
SPRO vs. SPRX - Dividend Comparison
Neither SPRO nor SPRX has paid dividends to shareholders.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 |
|---|---|---|---|---|---|---|
SPRO Spero Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SPRX Spear Alpha ETF | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.25% |
Frequently Asked Questions
SPRO and SPRX have a correlation of 0.26, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
SPRO has higher volatility (28.60%) compared to SPRX (21.39%). In terms of maximum drawdown, SPRO dropped -97.46% vs SPRX's -51.21%.
SPRX currently has the higher Sharpe Ratio (0.74 vs -0.78), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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