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REGN vs. VRTX
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between REGN and VRTX is 0.39, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Performance

REGN vs. VRTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Regeneron Pharmaceuticals, Inc. (REGN) and Vertex Pharmaceuticals Incorporated (VRTX). The values are adjusted to include any dividend payments, if applicable.

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Key characteristics

Sharpe Ratio

REGN:

-1.21

VRTX:

-0.02

Sortino Ratio

REGN:

-1.80

VRTX:

0.29

Omega Ratio

REGN:

0.78

VRTX:

1.04

Calmar Ratio

REGN:

-0.71

VRTX:

0.10

Martin Ratio

REGN:

-1.22

VRTX:

0.26

Ulcer Index

REGN:

32.36%

VRTX:

9.11%

Daily Std Dev

REGN:

32.05%

VRTX:

28.58%

Max Drawdown

REGN:

-91.81%

VRTX:

-91.77%

Current Drawdown

REGN:

-50.48%

VRTX:

-15.11%

Fundamentals

Market Cap

REGN:

$63.16B

VRTX:

$111.55B

EPS

REGN:

$39.37

VRTX:

-$3.83

PEG Ratio

REGN:

1.26

VRTX:

2.59

PS Ratio

REGN:

4.48

VRTX:

10.05

PB Ratio

REGN:

2.15

VRTX:

6.76

Total Revenue (TTM)

REGN:

$14.09B

VRTX:

$11.09B

Gross Profit (TTM)

REGN:

$11.96B

VRTX:

$9.54B

EBITDA (TTM)

REGN:

$4.98B

VRTX:

-$228.00M

Returns By Period

In the year-to-date period, REGN achieves a -16.46% return, which is significantly lower than VRTX's 8.93% return. Over the past 10 years, REGN has underperformed VRTX with an annualized return of 1.68%, while VRTX has yielded a comparatively higher 13.11% annualized return.


REGN

YTD

-16.46%

1M

8.20%

6M

-21.37%

1Y

-38.52%

5Y*

0.63%

10Y*

1.68%

VRTX

YTD

8.93%

1M

-9.72%

6M

-5.81%

1Y

-0.45%

5Y*

8.75%

10Y*

13.11%

*Annualized

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Risk-Adjusted Performance

REGN vs. VRTX — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

REGN
The Risk-Adjusted Performance Rank of REGN is 77
Overall Rank
The Sharpe Ratio Rank of REGN is 11
Sharpe Ratio Rank
The Sortino Ratio Rank of REGN is 33
Sortino Ratio Rank
The Omega Ratio Rank of REGN is 44
Omega Ratio Rank
The Calmar Ratio Rank of REGN is 88
Calmar Ratio Rank
The Martin Ratio Rank of REGN is 1616
Martin Ratio Rank

VRTX
The Risk-Adjusted Performance Rank of VRTX is 5050
Overall Rank
The Sharpe Ratio Rank of VRTX is 5050
Sharpe Ratio Rank
The Sortino Ratio Rank of VRTX is 4444
Sortino Ratio Rank
The Omega Ratio Rank of VRTX is 4545
Omega Ratio Rank
The Calmar Ratio Rank of VRTX is 5656
Calmar Ratio Rank
The Martin Ratio Rank of VRTX is 5555
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

REGN vs. VRTX - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Regeneron Pharmaceuticals, Inc. (REGN) and Vertex Pharmaceuticals Incorporated (VRTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current REGN Sharpe Ratio is -1.21, which is lower than the VRTX Sharpe Ratio of -0.02. The chart below compares the historical Sharpe Ratios of REGN and VRTX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


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Dividends

REGN vs. VRTX - Dividend Comparison

REGN's dividend yield for the trailing twelve months is around 0.15%, while VRTX has not paid dividends to shareholders.


Drawdowns

REGN vs. VRTX - Drawdown Comparison

The maximum REGN drawdown since its inception was -91.81%, roughly equal to the maximum VRTX drawdown of -91.77%. Use the drawdown chart below to compare losses from any high point for REGN and VRTX. For additional features, visit the drawdowns tool.


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Volatility

REGN vs. VRTX - Volatility Comparison

Regeneron Pharmaceuticals, Inc. (REGN) has a higher volatility of 17.04% compared to Vertex Pharmaceuticals Incorporated (VRTX) at 13.52%. This indicates that REGN's price experiences larger fluctuations and is considered to be riskier than VRTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Financials

REGN vs. VRTX - Financials Comparison

This section allows you to compare key financial metrics between Regeneron Pharmaceuticals, Inc. and Vertex Pharmaceuticals Incorporated. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


2.00B3.00B4.00B5.00B20212022202320242025
3.03B
2.77B
(REGN) Total Revenue
(VRTX) Total Revenue
Values in USD except per share items

REGN vs. VRTX - Profitability Comparison

The chart below illustrates the profitability comparison between Regeneron Pharmaceuticals, Inc. and Vertex Pharmaceuticals Incorporated over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

80.0%82.0%84.0%86.0%88.0%90.0%92.0%94.0%20212022202320242025
84.7%
86.9%
(REGN) Gross Margin
(VRTX) Gross Margin
REGN - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on May 2025, Regeneron Pharmaceuticals, Inc. reported a gross profit of 2.56B and revenue of 3.03B. Therefore, the gross margin over that period was 84.7%.

VRTX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.41B and revenue of 2.77B. Therefore, the gross margin over that period was 86.9%.

REGN - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on May 2025, Regeneron Pharmaceuticals, Inc. reported an operating income of 591.70M and revenue of 3.03B, resulting in an operating margin of 19.5%.

VRTX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported an operating income of 630.10M and revenue of 2.77B, resulting in an operating margin of 22.8%.

REGN - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on May 2025, Regeneron Pharmaceuticals, Inc. reported a net income of 808.70M and revenue of 3.03B, resulting in a net margin of 26.7%.

VRTX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported a net income of 646.30M and revenue of 2.77B, resulting in a net margin of 23.3%.