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GMAB vs. VRTX
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Correlation

The correlation between GMAB and VRTX is 0.25, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Performance

GMAB vs. VRTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Genmab A/S (GMAB) and Vertex Pharmaceuticals Incorporated (VRTX). The values are adjusted to include any dividend payments, if applicable.

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Key characteristics

Sharpe Ratio

GMAB:

-0.72

VRTX:

0.05

Sortino Ratio

GMAB:

-0.83

VRTX:

0.09

Omega Ratio

GMAB:

0.89

VRTX:

1.01

Calmar Ratio

GMAB:

-0.38

VRTX:

-0.09

Martin Ratio

GMAB:

-1.06

VRTX:

-0.23

Ulcer Index

GMAB:

22.58%

VRTX:

9.47%

Daily Std Dev

GMAB:

33.22%

VRTX:

28.66%

Max Drawdown

GMAB:

-84.20%

VRTX:

-91.77%

Current Drawdown

GMAB:

-56.24%

VRTX:

-13.48%

Fundamentals

Market Cap

GMAB:

$13.11B

VRTX:

$114.53B

EPS

GMAB:

$1.70

VRTX:

-$3.83

PEG Ratio

GMAB:

1.11

VRTX:

2.65

PS Ratio

GMAB:

4.06

VRTX:

10.32

PB Ratio

GMAB:

2.47

VRTX:

6.93

Total Revenue (TTM)

GMAB:

$18.10B

VRTX:

$11.10B

Gross Profit (TTM)

GMAB:

$17.26B

VRTX:

$9.55B

EBITDA (TTM)

GMAB:

$6.62B

VRTX:

-$76.30M

Returns By Period

In the year-to-date period, GMAB achieves a 2.16% return, which is significantly lower than VRTX's 11.02% return. Over the past 10 years, GMAB has underperformed VRTX with an annualized return of 9.30%, while VRTX has yielded a comparatively higher 13.43% annualized return.


GMAB

YTD

2.16%

1M

2.55%

6M

0.76%

1Y

-23.83%

3Y*

-11.11%

5Y*

-6.89%

10Y*

9.30%

VRTX

YTD

11.02%

1M

-11.20%

6M

-3.76%

1Y

1.35%

3Y*

17.77%

5Y*

9.20%

10Y*

13.43%

*Annualized

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Genmab A/S

Go deeper with the Portfolio Analysis tool — backtest performance, assess risk, compare to benchmarks, and more

Risk-Adjusted Performance

GMAB vs. VRTX — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

GMAB
The Risk-Adjusted Performance Rank of GMAB is 1818
Overall Rank
The Sharpe Ratio Rank of GMAB is 1212
Sharpe Ratio Rank
The Sortino Ratio Rank of GMAB is 1515
Sortino Ratio Rank
The Omega Ratio Rank of GMAB is 1515
Omega Ratio Rank
The Calmar Ratio Rank of GMAB is 2626
Calmar Ratio Rank
The Martin Ratio Rank of GMAB is 2323
Martin Ratio Rank

VRTX
The Risk-Adjusted Performance Rank of VRTX is 4444
Overall Rank
The Sharpe Ratio Rank of VRTX is 5252
Sharpe Ratio Rank
The Sortino Ratio Rank of VRTX is 3939
Sortino Ratio Rank
The Omega Ratio Rank of VRTX is 3838
Omega Ratio Rank
The Calmar Ratio Rank of VRTX is 4545
Calmar Ratio Rank
The Martin Ratio Rank of VRTX is 4545
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

GMAB vs. VRTX - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Genmab A/S (GMAB) and Vertex Pharmaceuticals Incorporated (VRTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The current GMAB Sharpe Ratio is -0.72, which is lower than the VRTX Sharpe Ratio of 0.05. The chart below compares the historical Sharpe Ratios of GMAB and VRTX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


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Go to the full Sharpe Ratio tool to analyze any stock or portfolio. Customize time frames, set your own risk-free rate, and more

Dividends

GMAB vs. VRTX - Dividend Comparison

Neither GMAB nor VRTX has paid dividends to shareholders.


Tickers have no history of dividend payments

Drawdowns

GMAB vs. VRTX - Drawdown Comparison

The maximum GMAB drawdown since its inception was -84.20%, smaller than the maximum VRTX drawdown of -91.77%. Use the drawdown chart below to compare losses from any high point for GMAB and VRTX.


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Go to the full Drawdowns tool for more analysis options, including inflation-adjusted drawdowns, and more

Volatility

GMAB vs. VRTX - Volatility Comparison

The current volatility for Genmab A/S (GMAB) is 11.29%, while Vertex Pharmaceuticals Incorporated (VRTX) has a volatility of 13.43%. This indicates that GMAB experiences smaller price fluctuations and is considered to be less risky than VRTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Financials

GMAB vs. VRTX - Financials Comparison

This section allows you to compare key financial metrics between Genmab A/S and Vertex Pharmaceuticals Incorporated. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


1.00B2.00B3.00B4.00B5.00B6.00B20212022202320242025
715.00M
2.77B
(GMAB) Total Revenue
(VRTX) Total Revenue
Values in USD except per share items

GMAB vs. VRTX - Profitability Comparison

The chart below illustrates the profitability comparison between Genmab A/S and Vertex Pharmaceuticals Incorporated over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

Gross Margin
Operating Margin
Net Margin
Quarterly
Annual

85.0%90.0%95.0%100.0%20212022202320242025
94.1%
86.9%
(GMAB) Gross Margin
(VRTX) Gross Margin
GMAB - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on May 2025, Genmab A/S reported a gross profit of 673.00M and revenue of 715.00M. Therefore, the gross margin over that period was 94.1%.

VRTX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.41B and revenue of 2.77B. Therefore, the gross margin over that period was 86.9%.

GMAB - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on May 2025, Genmab A/S reported an operating income of 188.00M and revenue of 715.00M, resulting in an operating margin of 26.3%.

VRTX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported an operating income of 630.10M and revenue of 2.77B, resulting in an operating margin of 22.8%.

GMAB - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on May 2025, Genmab A/S reported a net income of 195.00M and revenue of 715.00M, resulting in a net margin of 27.3%.

VRTX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on May 2025, Vertex Pharmaceuticals Incorporated reported a net income of 646.30M and revenue of 2.77B, resulting in a net margin of 23.3%.