DOCS vs. OTPIX

Last updated Aug 1, 2026

DOCS (Doximity, Inc.) is a stock, while OTPIX (ProFunds NASDAQ-100 Fund) is Large Cap Growth Equities fund managed by ProFunds. Over the past 5 years, DOCS returned -19.51%/yr vs -12.36%/yr for OTPIX. Their 0.43 correlation means their historical movements had little consistent relationship.

Performance

DOCS vs. OTPIX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Doximity, Inc. (DOCS) and ProFunds NASDAQ-100 Fund (OTPIX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, DOCS achieves a -52.78% return, which is significantly lower than OTPIX's 10.39% return.

DOCS

• 1D: -1.55%
• 1M: -4.35%
• 6M: -44.20%
• YTD: -52.78%
• 1Y: -63.53%
• 3Y*: -15.61%
• 5Y*: -19.51%
• 10Y*: —
• ALL TIME*: -12.44%

OTPIX

• 1D: 3.35%
• 1M: -4.29%
• 6M: 9.21%
• YTD: 10.39%
• 1Y: 21.79%
• 3Y*: -24.71%
• 5Y*: -12.36%
• 10Y*: 4.33%
• ALL TIME*: 5.52%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
DOCS Doximity, Inc.	$69.10M	$63.08M	$85.82M
OTPIX ProFunds NASDAQ-100 Fund	$0.00	$0.00	$0.00

DOCS vs. OTPIX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
DOCS Doximity, Inc.	-52.78%	-17.06%	90.41%	-16.45%	-33.05%	21.76%
OTPIX ProFunds NASDAQ-100 Fund	10.39%	18.08%	-69.20%	51.66%	-34.36%	35.40%

Correlation

The correlation between DOCS and OTPIX is 0.19, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.19
Correlation (3Y) Balances recent behavior with more history.	0.36
Correlation (5Y) Shows whether the relationship held over a longer period.	0.44
Correlation (All Time) Calculated using the full available price history since Jun 24, 2021	0.43

Over the past year, the correlation between DOCS and OTPIX has dropped to 0.19 - well below their long-term average of 0.43, suggesting their price drivers have been diverging.

Return for Risk

DOCS vs. OTPIX — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

DOCS

DOCS Risk / Return Rank: 7
DOCS Sharpe Ratio Rank: 2
DOCS Sortino Ratio Rank: 3
DOCS Omega Ratio Rank: 2
DOCS Calmar Ratio Rank: 10
DOCS Martin Ratio Rank: 15

OTPIX

OTPIX Risk / Return Rank: 31
OTPIX Sharpe Ratio Rank: 30
OTPIX Sortino Ratio Rank: 29
OTPIX Omega Ratio Rank: 29
OTPIX Calmar Ratio Rank: 36
OTPIX Martin Ratio Rank: 33

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

DOCS vs. OTPIX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Doximity, Inc. (DOCS) and ProFunds NASDAQ-100 Fund (OTPIX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	DOCS	OTPIX	Difference
Sharpe ratio: Return per unit of total volatility	-1.18	0.98	-2.16
Sortino ratio: Return per unit of downside risk	-1.92	1.42	-3.35
Omega ratio: Gain probability vs. loss probability	0.73	1.18	-0.45
Calmar ratio: Return relative to maximum drawdown	-0.85	1.51	-2.36
Martin ratio: Return relative to average drawdown	-1.23	4.80	-6.03

DOCS vs. OTPIX - Sharpe Ratio Comparison

The current DOCS Sharpe Ratio is -1.18, which is lower than the OTPIX Sharpe Ratio of 0.98. The chart below compares the historical Sharpe Ratios of DOCS and OTPIX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

DOCS vs. OTPIX - Drawdown Comparison

The maximum DOCS drawdown since its inception was -82.35%, roughly equal to the maximum OTPIX drawdown of -79.55%. Use the drawdown chart below to compare losses from any high point for DOCS and OTPIX.

Drawdown Indicators

	DOCS	OTPIX	Difference
Max Drawdown Largest peak-to-trough decline	-82.35%	-79.55%	-2.80%
Max Drawdown (1Y) Largest decline over 1 year	-76.03%	-12.53%	-63.50%
Max Drawdown (3Y) Largest decline over 3 years	-78.34%	-79.55%	+1.21%
Max Drawdown (5Y) Largest decline over 5 years	-82.35%	-79.55%	-2.80%
Max Drawdown (10Y) Largest decline over 10 years	—	-79.55%	—
Current Drawdown Current decline from peak	-79.50%	-67.10%	-12.40%
Average Drawdown Average peak-to-trough decline	-57.75%	-23.06%	-34.69%
Ulcer Index Depth and duration of drawdowns from previous peaks	52.35%	3.93%	+48.42%

Volatility

DOCS vs. OTPIX - Volatility Comparison

Doximity, Inc. (DOCS) has a higher volatility of 10.69% compared to ProFunds NASDAQ-100 Fund (OTPIX) at 6.87%. This indicates that DOCS's price experiences larger fluctuations and is considered to be riskier than OTPIX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	DOCS	OTPIX	Difference
Volatility (1M) Calculated over the trailing 1-month period	10.69%	6.87%	+3.82%
Volatility (6M) Calculated over the trailing 6-month period	45.39%	15.96%	+29.43%
Volatility (1Y) Calculated over the trailing 1-year period	54.64%	19.33%	+35.31%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	67.87%	42.03%	+25.84%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	69.45%	33.34%	+36.11%

Dividends

DOCS vs. OTPIX - Dividend Comparison

DOCS has not paid dividends to shareholders, while OTPIX's dividend yield for the trailing twelve months is around 1.56%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019
DOCS Doximity, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%
OTPIX ProFunds NASDAQ-100 Fund	1.56%	1.72%	0.76%	0.00%	0.00%	18.31%	1.10%	0.87%

Frequently Asked Questions

Can I hold both DOCS and OTPIX in my portfolio?

DOCS and OTPIX have a correlation of 0.19, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, DOCS or OTPIX?

DOCS has higher volatility (10.69%) compared to OTPIX (6.87%). In terms of maximum drawdown, DOCS dropped -82.35% vs OTPIX's -79.55%.

Which has better risk-adjusted returns?

OTPIX currently has the higher Sharpe Ratio (0.98 vs -1.18), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.