BMRN vs. VRTX
BMRN (BioMarin Pharmaceutical Inc.) and VRTX (Vertex Pharmaceuticals Incorporated) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, BMRN returned -3.05%/yr vs 19.05%/yr for VRTX. At a 0.41 correlation, their price movements are largely independent.
Performance
BMRN vs. VRTX - Performance Comparison
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Returns By Period
In the year-to-date period, BMRN achieves a -4.93% return, which is significantly lower than VRTX's 3.32% return. Over the past 10 years, BMRN has underperformed VRTX with an annualized return of -3.05%, while VRTX has yielded a comparatively higher 19.05% annualized return.
BMRN
- 1D
- 1.07%
- 1M
- 4.46%
- YTD
- -4.93%
- 6M
- -7.59%
- 1Y
- 4.47%
- 3Y*
- -15.46%
- 5Y*
- -7.58%
- 10Y*
- -3.05%
VRTX
- 1D
- 0.35%
- 1M
- 7.80%
- YTD
- 3.32%
- 6M
- 2.01%
- 1Y
- 5.61%
- 3Y*
- 10.52%
- 5Y*
- 19.53%
- 10Y*
- 19.05%
BMRN vs. VRTX - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
BMRN BioMarin Pharmaceutical Inc. | -4.93% | -9.58% | -31.83% | -6.83% | 17.14% | 0.75% | 3.71% | -0.70% | -4.51% | 7.64% |
VRTX Vertex Pharmaceuticals Incorporated | 3.32% | 12.58% | -1.03% | 40.90% | 31.50% | -7.08% | 7.94% | 32.13% | 10.58% | 103.42% |
Correlation
The correlation between BMRN and VRTX is 0.45, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.45 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.36 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.41 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.49 |
Correlation (All Time) Calculated using the full available price history since Jul 26, 1999 | 0.41 |
The correlation between BMRN and VRTX shifts across timeframes, from 0.36 (3 years) to 0.49 (10 years), reflecting how their relationship changes across market environments.
Fundamentals
BMRN:
$11.17B
VRTX:
$120.06B
BMRN:
$1.37
VRTX:
$16.87
BMRN:
41.19
VRTX:
27.77
BMRN:
2.47
VRTX:
2.31
BMRN:
3.41
VRTX:
9.83
BMRN:
1.80
VRTX:
4.53
BMRN:
$3.24B
VRTX:
$12.26B
BMRN:
$2.46B
VRTX:
$10.57B
BMRN:
$439.56M
VRTX:
$5.19B
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Return for Risk
BMRN vs. VRTX — Risk / Return Rank
BMRN
VRTX
BMRN vs. VRTX - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for BioMarin Pharmaceutical Inc. (BMRN) and Vertex Pharmaceuticals Incorporated (VRTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| BMRN | VRTX | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -0.04 | ||
| Sortino ratioReturn per unit of downside risk | +0.07 | ||
| Omega ratioGain probability vs. loss probability | 1.06 | 1.07 | -0.01 |
| Calmar ratioReturn relative to maximum drawdown | 0.20 | 0.24 | -0.04 |
| Martin ratioReturn relative to average drawdown | 0.40 | 0.50 | -0.09 |
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Drawdowns
BMRN vs. VRTX - Drawdown Comparison
The maximum BMRN drawdown since its inception was -90.58%, roughly equal to the maximum VRTX drawdown of -91.77%. Use the drawdown chart below to compare losses from any high point for BMRN and VRTX.
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Drawdown Indicators
| BMRN | VRTX | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -90.58% | -91.77% | +1.19% |
Max Drawdown (1Y)Largest decline over 1 year | -22.49% | -23.56% | +1.07% |
Max Drawdown (3Y)Largest decline over 3 years | -49.83% | -29.07% | -20.76% |
Max Drawdown (5Y)Largest decline over 5 years | -57.64% | -29.07% | -28.57% |
Max Drawdown (10Y)Largest decline over 10 years | -62.09% | -41.60% | -20.49% |
Current DrawdownCurrent decline from peak | -62.11% | -9.35% | -52.76% |
Average DrawdownAverage peak-to-trough decline | -45.54% | -37.71% | -7.83% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 11.17% | 11.35% | -0.18% |
Volatility
BMRN vs. VRTX - Volatility Comparison
BioMarin Pharmaceutical Inc. (BMRN) has a higher volatility of 12.20% compared to Vertex Pharmaceuticals Incorporated (VRTX) at 7.70%. This indicates that BMRN's price experiences larger fluctuations and is considered to be riskier than VRTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| BMRN | VRTX | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 12.20% | 7.70% | +4.50% |
Volatility (6M)Calculated over the trailing 6-month period | 28.14% | 21.02% | +7.12% |
Volatility (1Y)Calculated over the trailing 1-year period | 34.78% | 34.18% | +0.60% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 32.88% | 28.56% | +4.32% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 35.36% | 32.74% | +2.62% |
Dividends
BMRN vs. VRTX - Dividend Comparison
Neither BMRN nor VRTX has paid dividends to shareholders.
Financials
BMRN vs. VRTX - Financials Comparison
This section allows you to compare key financial metrics between BioMarin Pharmaceutical Inc. and Vertex Pharmaceuticals Incorporated. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
BMRN vs. VRTX - Profitability Comparison
BMRN - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, BioMarin Pharmaceutical Inc. reported a gross profit of 571.21M and revenue of 766.21M. Therefore, the gross margin over that period was 74.6%.
VRTX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.59B and revenue of 2.99B. Therefore, the gross margin over that period was 86.9%.
BMRN - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, BioMarin Pharmaceutical Inc. reported an operating income of 129.64M and revenue of 766.21M, resulting in an operating margin of 16.9%.
VRTX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported an operating income of 1.14B and revenue of 2.99B, resulting in an operating margin of 38.1%.
BMRN - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, BioMarin Pharmaceutical Inc. reported a net income of 105.53M and revenue of 766.21M, resulting in a net margin of 13.8%.
VRTX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a net income of 1.03B and revenue of 2.99B, resulting in a net margin of 34.5%.
Frequently Asked Questions
BMRN and VRTX have a correlation of 0.45, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
BMRN has higher volatility (12.20%) compared to VRTX (7.70%). In terms of maximum drawdown, BMRN dropped -90.58% vs VRTX's -91.77%.
VRTX currently has the higher Sharpe Ratio (0.16 vs 0.13), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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