AXSM vs. NVO
AXSM (Axsome Therapeutics, Inc.) and NVO (Novo Nordisk A/S) are both stocks. Both are in the Healthcare sector — AXSM in Biotechnology, NVO in Drug Manufacturers - General. Over the past 10 years, AXSM returned 39.83%/yr vs 7.55%/yr for NVO. Their 0.15 correlation means their historical movements had little consistent relationship.
Performance
AXSM vs. NVO - Performance Comparison
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Returns By Period
In the year-to-date period, AXSM achieves a 19.36% return, which is significantly higher than NVO's -4.23% return. Over the past 10 years, AXSM has outperformed NVO with an annualized return of 39.83%, while NVO has yielded a comparatively lower 7.55% annualized return.
AXSM
- 1D
- -7.10%
- 1M
- -10.77%
- 6M
- 18.31%
- YTD
- 19.36%
- 1Y
- 111.60%
- 3Y*
- 41.26%
- 5Y*
- 35.01%
- 10Y*
- 39.83%
- ALL TIME*
- 34.71%
NVO
- 1D
- -8.78%
- 1M
- -6.64%
- 6M
- -18.01%
- YTD
- -4.23%
- 1Y
- 2.25%
- 3Y*
- -14.32%
- 5Y*
- 2.48%
- 10Y*
- 7.55%
- ALL TIME*
- 14.37%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $153.10M | $171.36M | $209.26M | |
| $504.41M | $480.49M | $577.88M |
AXSM vs. NVO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
AXSM Axsome Therapeutics, Inc. | 19.36% | 115.86% | 6.31% | 3.19% | 104.16% | -53.63% | -21.18% | 3,565.25% | -49.64% | -17.04% |
NVO Novo Nordisk A/S | -4.23% | -39.22% | -15.93% | 54.84% | 22.66% | 63.52% | 23.33% | 28.70% | -12.98% | 52.92% |
Correlation
The correlation between AXSM and NVO is 0.18, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.18 |
Correlation (3Y) Balances recent behavior with more history. | 0.16 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.19 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.15 |
Correlation (All Time) Calculated using the full available price history since Nov 19, 2015 | 0.15 |
Fundamentals
AXSM:
$11.22B
NVO:
$209.19B
AXSM:
-$3.72
NVO:
DKK 27.42
AXSM:
15.58
NVO:
4.15
AXSM:
204.46
NVO:
6.70
AXSM:
$708.24M
NVO:
DKK 327.80B
AXSM:
$655.82M
NVO:
DKK 268.30B
AXSM:
-$172.72M
NVO:
DKK 181.54B
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Return for Risk
AXSM vs. NVO — Risk / Return Rank
AXSM
NVO
AXSM vs. NVO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Axsome Therapeutics, Inc. (AXSM) and Novo Nordisk A/S (NVO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| AXSM | NVO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +2.59 | ||
| Sortino ratioReturn per unit of downside risk | +3.47 | ||
| Omega ratioGain probability vs. loss probability | 1.47 | 1.06 | +0.41 |
| Calmar ratioReturn relative to maximum drawdown | 6.25 | 0.11 | +6.15 |
| Martin ratioReturn relative to average drawdown | 18.02 | 0.20 | +17.82 |
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Drawdowns
AXSM vs. NVO - Drawdown Comparison
The maximum AXSM drawdown since its inception was -86.65%, which is greater than NVO's maximum drawdown of -74.70%. Use the drawdown chart below to compare losses from any high point for AXSM and NVO.
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Drawdown Indicators
| AXSM | NVO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -86.65% | -74.70% | -11.95% |
Max Drawdown (1Y)Largest decline over 1 year | -18.50% | -43.67% | +25.17% |
Max Drawdown (3Y)Largest decline over 3 years | -32.69% | -74.70% | +42.01% |
Max Drawdown (5Y)Largest decline over 5 years | -61.08% | -74.70% | +13.62% |
Max Drawdown (10Y)Largest decline over 10 years | -81.26% | -74.70% | -6.56% |
Current DrawdownCurrent decline from peak | -14.57% | -65.79% | +51.22% |
Average DrawdownAverage peak-to-trough decline | -39.06% | -17.93% | -21.13% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 6.41% | 23.97% | -17.56% |
Volatility
AXSM vs. NVO - Volatility Comparison
Axsome Therapeutics, Inc. (AXSM) has a higher volatility of 14.94% compared to Novo Nordisk A/S (NVO) at 12.28%. This indicates that AXSM's price experiences larger fluctuations and is considered to be riskier than NVO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| AXSM | NVO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 14.94% | 12.28% | +2.66% |
Volatility (6M)Calculated over the trailing 6-month period | 28.72% | 36.87% | -8.15% |
Volatility (1Y)Calculated over the trailing 1-year period | 42.96% | 46.77% | -3.81% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 70.11% | 38.76% | +31.35% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 90.38% | 32.76% | +57.62% |
Dividends
AXSM vs. NVO - Dividend Comparison
AXSM has not paid dividends to shareholders, while NVO's dividend yield for the trailing twelve months is around 3.83%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AXSM Axsome Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
NVO Novo Nordisk A/S | 3.83% | 3.31% | 1.68% | 1.00% | 1.20% | 1.35% | 1.87% | 2.14% | 1.45% | 1.52% | 2.87% | 0.92% |
Financials
AXSM vs. NVO - Financials Comparison
This section allows you to compare key financial metrics between Axsome Therapeutics, Inc. and Novo Nordisk A/S. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
AXSM vs. NVO - Profitability Comparison
AXSM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Axsome Therapeutics, Inc. reported a gross profit of 176.48M and revenue of 191.20M. Therefore, the gross margin over that period was 92.3%.
NVO - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Novo Nordisk A/S reported a gross profit of 83.23B and revenue of 96.82B. Therefore, the gross margin over that period was 86.0%.
AXSM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Axsome Therapeutics, Inc. reported an operating income of -63.36M and revenue of 191.20M, resulting in an operating margin of -33.1%.
NVO - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Novo Nordisk A/S reported an operating income of 59.62B and revenue of 96.82B, resulting in an operating margin of 61.6%.
AXSM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Axsome Therapeutics, Inc. reported a net income of -64.54M and revenue of 191.20M, resulting in a net margin of -33.8%.
NVO - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Novo Nordisk A/S reported a net income of 48.56B and revenue of 96.82B, resulting in a net margin of 50.2%.
Frequently Asked Questions
AXSM and NVO have a correlation of 0.18, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
AXSM has higher volatility (14.94%) compared to NVO (12.28%). In terms of maximum drawdown, AXSM dropped -86.65% vs NVO's -74.70%.
AXSM currently has the higher Sharpe Ratio (2.69 vs 0.10), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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