AXSM vs. NVO
AXSM (Axsome Therapeutics, Inc.) and NVO (Novo Nordisk A/S) are both stocks. Both are in the Healthcare sector — AXSM in Biotechnology, NVO in Drug Manufacturers - General. Over the past 10 years, AXSM returned 42.31%/yr vs 8.62%/yr for NVO. At a 0.15 correlation, their price movements are largely independent.
Performance
AXSM vs. NVO - Performance Comparison
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Returns By Period
In the year-to-date period, AXSM achieves a 32.48% return, which is significantly higher than NVO's -3.54% return. Over the past 10 years, AXSM has outperformed NVO with an annualized return of 42.31%, while NVO has yielded a comparatively lower 8.62% annualized return.
AXSM
- 1D
- -2.37%
- 1M
- 2.54%
- YTD
- 32.48%
- 6M
- 56.93%
- 1Y
- 138.04%
- 3Y*
- 40.04%
- 5Y*
- 27.97%
- 10Y*
- 42.31%
NVO
- 1D
- 3.36%
- 1M
- 5.47%
- YTD
- -3.54%
- 6M
- -4.91%
- 1Y
- -28.81%
- 3Y*
- -13.64%
- 5Y*
- 5.10%
- 10Y*
- 8.62%
AXSM vs. NVO - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
AXSM Axsome Therapeutics, Inc. | 32.48% | 115.86% | 6.31% | 3.19% | 104.16% | -53.63% | -21.18% | 3,565.25% | -49.64% | -17.04% |
NVO Novo Nordisk A/S | -3.54% | -39.22% | -15.93% | 54.84% | 22.66% | 63.52% | 23.33% | 28.70% | -12.98% | 52.92% |
Correlation
The correlation between AXSM and NVO is 0.17, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.17 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.16 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.18 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.15 |
Correlation (All Time) Calculated using the full available price history since Nov 19, 2015 | 0.15 |
Fundamentals
AXSM:
$12.39B
NVO:
$210.96B
AXSM:
-$3.74
NVO:
DKK 27.42
AXSM:
17.19
NVO:
4.21
AXSM:
226.95
NVO:
6.80
AXSM:
$708.24M
NVO:
DKK 327.80B
AXSM:
$655.82M
NVO:
DKK 268.30B
AXSM:
-$172.72M
NVO:
DKK 181.54B
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Return for Risk
AXSM vs. NVO — Risk / Return Rank
AXSM
NVO
AXSM vs. NVO - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Axsome Therapeutics, Inc. (AXSM) and Novo Nordisk A/S (NVO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| AXSM | NVO | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +3.88 | ||
| Sortino ratioReturn per unit of downside risk | +5.20 | ||
| Omega ratioGain probability vs. loss probability | 1.57 | 0.93 | +0.64 |
| Calmar ratioReturn relative to maximum drawdown | 7.51 | -0.59 | +8.09 |
| Martin ratioReturn relative to average drawdown | 22.08 | -0.93 | +23.02 |
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Drawdowns
AXSM vs. NVO - Drawdown Comparison
The maximum AXSM drawdown since its inception was -86.65%, which is greater than NVO's maximum drawdown of -74.70%. Use the drawdown chart below to compare losses from any high point for AXSM and NVO.
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Drawdown Indicators
| AXSM | NVO | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -86.65% | -74.70% | -11.95% |
Max Drawdown (1Y)Largest decline over 1 year | -18.50% | -49.17% | +30.67% |
Max Drawdown (3Y)Largest decline over 3 years | -34.83% | -74.70% | +39.87% |
Max Drawdown (5Y)Largest decline over 5 years | -72.91% | -74.70% | +1.79% |
Max Drawdown (10Y)Largest decline over 10 years | -81.26% | -74.70% | -6.56% |
Current DrawdownCurrent decline from peak | -5.17% | -65.54% | +60.37% |
Average DrawdownAverage peak-to-trough decline | -39.39% | -17.81% | -21.58% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 6.28% | 30.87% | -24.59% |
Volatility
AXSM vs. NVO - Volatility Comparison
The current volatility for Axsome Therapeutics, Inc. (AXSM) is 9.26%, while Novo Nordisk A/S (NVO) has a volatility of 12.04%. This indicates that AXSM experiences smaller price fluctuations and is considered to be less risky than NVO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| AXSM | NVO | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 9.26% | 12.04% | -2.78% |
Volatility (6M)Calculated over the trailing 6-month period | 33.26% | 38.41% | -5.15% |
Volatility (1Y)Calculated over the trailing 1-year period | 41.75% | 52.06% | -10.31% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 70.26% | 38.48% | +31.78% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 90.40% | 32.58% | +57.82% |
Dividends
AXSM vs. NVO - Dividend Comparison
AXSM has not paid dividends to shareholders, while NVO's dividend yield for the trailing twelve months is around 3.80%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
AXSM Axsome Therapeutics, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
NVO Novo Nordisk A/S | 3.80% | 3.31% | 1.68% | 1.00% | 1.20% | 1.35% | 1.87% | 2.14% | 1.45% | 1.52% | 2.87% | 0.92% |
Financials
AXSM vs. NVO - Financials Comparison
This section allows you to compare key financial metrics between Axsome Therapeutics, Inc. and Novo Nordisk A/S. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
AXSM vs. NVO - Profitability Comparison
AXSM - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported a gross profit of 176.48M and revenue of 191.20M. Therefore, the gross margin over that period was 92.3%.
NVO - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Novo Nordisk A/S reported a gross profit of 83.23B and revenue of 96.82B. Therefore, the gross margin over that period was 86.0%.
AXSM - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported an operating income of -63.36M and revenue of 191.20M, resulting in an operating margin of -33.1%.
NVO - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Novo Nordisk A/S reported an operating income of 59.62B and revenue of 96.82B, resulting in an operating margin of 61.6%.
AXSM - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Axsome Therapeutics, Inc. reported a net income of -64.54M and revenue of 191.20M, resulting in a net margin of -33.8%.
NVO - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Novo Nordisk A/S reported a net income of 48.56B and revenue of 96.82B, resulting in a net margin of 50.2%.
Frequently Asked Questions
AXSM and NVO have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
NVO has higher volatility (12.04%) compared to AXSM (9.26%). In terms of maximum drawdown, AXSM dropped -86.65% vs NVO's -74.70%.
AXSM currently has the higher Sharpe Ratio (3.33 vs -0.56), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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