AMX vs. VRTX

Last updated Jun 3, 2026

AMX (América Móvil, S.A.B. de C.V.) and VRTX (Vertex Pharmaceuticals Incorporated) are both stocks. AMX operates in Telecom Services (Communication Services), while VRTX operates in Biotechnology (Healthcare). Over the past 10 years, AMX returned 10.67%/yr vs 16.29%/yr for VRTX. At a 0.25 correlation, their price movements are largely independent.

Performance

AMX vs. VRTX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in América Móvil, S.A.B. de C.V. (AMX) and Vertex Pharmaceuticals Incorporated (VRTX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, AMX achieves a 24.38% return, which is significantly higher than VRTX's -6.24% return. Over the past 10 years, AMX has underperformed VRTX with an annualized return of 10.67%, while VRTX has yielded a comparatively higher 16.29% annualized return.

AMX

• 1D: 2.02%
• 1M: -2.43%
• YTD: 24.38%
• 6M: 14.37%
• 1Y: 55.18%
• 3Y*: 8.60%
• 5Y*: 14.52%
• 10Y*: 10.67%

VRTX

• 1D: -3.04%
• 1M: 0.28%
• YTD: -6.24%
• 6M: -1.86%
• 1Y: -4.57%
• 3Y*: 8.39%
• 5Y*: 15.02%
• 10Y*: 16.29%

*Multi-year figures are annualized to reflect compound growth (CAGR)

AMX vs. VRTX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
AMX América Móvil, S.A.B. de C.V.	24.38%	48.56%	-20.36%	4.60%	-9.82%	48.68%	-6.62%	15.01%	-15.29%	39.13%
VRTX Vertex Pharmaceuticals Incorporated	-6.24%	12.58%	-1.03%	40.90%	31.50%	-7.08%	7.94%	32.13%	10.58%	103.42%

Correlation

The correlation between AMX and VRTX is 0.12, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.12
Correlation (3Y) Calculated over the trailing 3-year period	0.10
Correlation (5Y) Calculated over the trailing 5-year period	0.16
Correlation (10Y) Calculated over the trailing 10-year period	0.19
Correlation (All Time) Calculated using the full available price history since Feb 9, 2001	0.25

The correlation between AMX and VRTX shifts across timeframes, from 0.10 (3 years) to 0.25 (all time), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap AMX : $77.71B VRTX : $108.95B
EPS AMX : $29.05 VRTX : $16.87
PE Ratio AMX : 0.89 VRTX : 25.20
PEG Ratio AMX : 0.02 VRTX : 2.10
PS Ratio AMX : 0.08 VRTX : 8.92
PB Ratio AMX : 0.18 VRTX : 4.11
Total Revenue (TTM) AMX : $944.51B VRTX : $12.26B
Gross Profit (TTM) AMX : $453.55B VRTX : $10.57B
EBITDA (TTM) AMX : $383.46B VRTX : $5.19B

Return for Risk

AMX vs. VRTX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

AMX

AMX Risk / Return Rank: 87
AMX Sharpe Ratio Rank: 89
AMX Sortino Ratio Rank: 89
AMX Omega Ratio Rank: 86
AMX Calmar Ratio Rank: 86
AMX Martin Ratio Rank: 87

VRTX

VRTX Risk / Return Rank: 33
VRTX Sharpe Ratio Rank: 35
VRTX Sortino Ratio Rank: 31
VRTX Omega Ratio Rank: 31
VRTX Calmar Ratio Rank: 35
VRTX Martin Ratio Rank: 33

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

AMX vs. VRTX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for América Móvil, S.A.B. de C.V. (AMX) and Vertex Pharmaceuticals Incorporated (VRTX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	AMX	VRTX	Difference
Sharpe ratio Return per unit of total volatility	2.15	-0.14	+2.28
Sortino ratio Return per unit of downside risk	3.13	0.05	+3.08
Omega ratio Gain probability vs. loss probability	1.38	1.01	+0.38
Calmar ratio Return relative to maximum drawdown	3.68	-0.16	+3.84
Martin ratio Return relative to average drawdown	10.11	-0.35	+10.45
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

AMX vs. VRTX - Sharpe Ratio Comparison

The current AMX Sharpe Ratio is 2.15, which is higher than the VRTX Sharpe Ratio of -0.14. The chart below compares the historical Sharpe Ratios of AMX and VRTX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	AMX	VRTX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.15	-0.14	+2.28
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.57	0.52	+0.05
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.37	0.50	-0.13
Sharpe Ratio (All Time) Calculated using the full available price history	0.32	0.25	+0.07

Drawdowns

AMX vs. VRTX - Drawdown Comparison

The maximum AMX drawdown since its inception was -64.34%, smaller than the maximum VRTX drawdown of -91.77%. Use the drawdown chart below to compare losses from any high point for AMX and VRTX.

Drawdown Indicators

	AMX	VRTX	Difference
Max Drawdown Largest peak-to-trough decline	-64.34%	-91.77%	+27.43%
Max Drawdown (1Y) Largest decline over 1 year	-15.36%	-23.56%	+8.20%
Max Drawdown (3Y) Largest decline over 3 years	-36.73%	-29.07%	-7.66%
Max Drawdown (5Y) Largest decline over 5 years	-38.08%	-29.07%	-9.01%
Max Drawdown (10Y) Largest decline over 10 years	-44.45%	-41.60%	-2.85%
Current Drawdown Current decline from peak	-6.24%	-17.74%	+11.50%
Average Drawdown Average peak-to-trough decline	-24.12%	-37.70%	+13.58%
Ulcer Index Depth and duration of drawdowns from previous peaks	5.59%	11.11%	-5.52%

Volatility

AMX vs. VRTX - Volatility Comparison

The current volatility for América Móvil, S.A.B. de C.V. (AMX) is 5.55%, while Vertex Pharmaceuticals Incorporated (VRTX) has a volatility of 7.13%. This indicates that AMX experiences smaller price fluctuations and is considered to be less risky than VRTX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	AMX	VRTX	Difference
Volatility (1M) Calculated over the trailing 1-month period	5.55%	7.13%	-1.58%
Volatility (6M) Calculated over the trailing 6-month period	20.55%	21.76%	-1.21%
Volatility (1Y) Calculated over the trailing 1-year period	25.84%	33.88%	-8.04%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	25.73%	28.90%	-3.17%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	29.02%	32.83%	-3.81%

Dividends

AMX vs. VRTX - Dividend Comparison

AMX's dividend yield for the trailing twelve months is around 2.16%, while VRTX has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
AMX América Móvil, S.A.B. de C.V.	2.16%	2.68%	3.59%	2.83%	4.41%	1.88%	2.49%	2.29%	2.24%	1.91%	2.27%	8.55%
VRTX Vertex Pharmaceuticals Incorporated	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Financials

AMX vs. VRTX - Profitability Comparison

The chart below illustrates the profitability comparison between América Móvil, S.A.B. de C.V. and Vertex Pharmaceuticals Incorporated over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

AMX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, América Móvil, S.A.B. de C.V. reported a gross profit of 148.31B and revenue of 236.84B. Therefore, the gross margin over that period was 62.6%.

VRTX - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a gross profit of 2.59B and revenue of 2.99B. Therefore, the gross margin over that period was 86.9%.

AMX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, América Móvil, S.A.B. de C.V. reported an operating income of 50.52B and revenue of 236.84B, resulting in an operating margin of 21.3%.

VRTX - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported an operating income of 1.14B and revenue of 2.99B, resulting in an operating margin of 38.1%.

AMX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, América Móvil, S.A.B. de C.V. reported a net income of 23.40B and revenue of 236.84B, resulting in a net margin of 9.9%.

VRTX - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Vertex Pharmaceuticals Incorporated reported a net income of 1.03B and revenue of 2.99B, resulting in a net margin of 34.5%.

Frequently Asked Questions

Can I hold both AMX and VRTX in my portfolio?

AMX and VRTX have a correlation of 0.12, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, AMX or VRTX?

VRTX has higher volatility (7.13%) compared to AMX (5.55%). In terms of maximum drawdown, AMX dropped -64.34% vs VRTX's -91.77%.

Which has better risk-adjusted returns?

AMX currently has the higher Sharpe Ratio (2.15 vs -0.14), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.