ACON vs. OPK

Last updated Apr 1, 2026

Compare and contrast key facts about Aclarion Inc (ACON) and OPKO Health, Inc. (OPK).

Performance

ACON vs. OPK - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Aclarion Inc (ACON) and OPKO Health, Inc. (OPK). The values are adjusted to include any dividend payments, if applicable.

ACON vs. OPK - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022
ACON Aclarion Inc	-28.91%	-99.65%	-95.50%	-65.52%	-78.68%
OPK OPKO Health, Inc.	-9.52%	-14.29%	-2.65%	20.80%	-57.34%

Fundamentals

EPS ACON : -$12.59 OPK : -$0.31
PS Ratio ACON : 28.22 OPK : 1.39
Total Revenue (TTM) ACON : $67.48K OPK : $606.93M
Gross Profit (TTM) ACON : -$5.29K OPK : $251.79M
EBITDA (TTM) ACON : -$7.12M OPK : -$66.36M

Returns By Period

In the year-to-date period, ACON achieves a -28.91% return, which is significantly lower than OPK's -9.52% return.

ACON

• 1D: 6.17%
• 1M: 19.34%
• YTD: -28.91%
• 6M: -56.40%
• 1Y: -69.72%
• 3Y*: -96.74%
• 5Y*: —
• 10Y*: —

OPK

• 1D: 3.64%
• 1M: -5.00%
• YTD: -9.52%
• 6M: -26.45%
• 1Y: -31.33%
• 3Y*: -7.92%
• 5Y*: -23.60%
• 10Y*: -19.84%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

ACON vs. OPK — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ACON

ACON Risk / Return Rank: 11
ACON Sharpe Ratio Rank: 12
ACON Sortino Ratio Rank: 11
ACON Omega Ratio Rank: 11
ACON Calmar Ratio Rank: 8
ACON Martin Ratio Rank: 12

OPK

OPK Risk / Return Rank: 8
OPK Sharpe Ratio Rank: 8
OPK Sortino Ratio Rank: 10
OPK Omega Ratio Rank: 12
OPK Calmar Ratio Rank: 3
OPK Martin Ratio Rank: 6

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ACON vs. OPK - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Aclarion Inc (ACON) and OPKO Health, Inc. (OPK). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ACON	OPK	Difference
Sharpe ratio Return per unit of total volatility	-0.71	-0.83	+0.13
Sortino ratio Return per unit of downside risk	-0.99	-1.13	+0.14
Omega ratio Gain probability vs. loss probability	0.87	0.87	0.00
Calmar ratio Return relative to maximum drawdown	-0.90	-0.98	+0.08
Martin ratio Return relative to average drawdown	-1.41	-1.64	+0.23
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ACON vs. OPK - Sharpe Ratio Comparison

The current ACON Sharpe Ratio is -0.71, which is comparable to the OPK Sharpe Ratio of -0.83. The chart below compares the historical Sharpe Ratios of ACON and OPK, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	ACON	OPK	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.71	-0.83	+0.13
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.42	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.31	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.54	-0.05	-0.48

Correlation

The correlation between ACON and OPK is 0.09, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

ACON vs. OPK - Dividend Comparison

Neither ACON nor OPK has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

ACON vs. OPK - Drawdown Comparison

The maximum ACON drawdown since its inception was -100.00%, roughly equal to the maximum OPK drawdown of -98.17%. Use the drawdown chart below to compare losses from any high point for ACON and OPK.

Drawdown Indicators

	ACON	OPK	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-98.17%	-1.83%
Max Drawdown (1Y) Largest decline over 1 year	-81.28%	-33.73%	-47.55%
Max Drawdown (5Y) Largest decline over 5 years	—	-83.19%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-92.73%	—
Current Drawdown Current decline from peak	-100.00%	-94.04%	-5.96%
Average Drawdown Average peak-to-trough decline	-87.33%	-72.98%	-14.35%
Ulcer Index Depth and duration of drawdowns from previous peaks	51.64%	20.10%	+31.54%

Volatility

ACON vs. OPK - Volatility Comparison

Aclarion Inc (ACON) has a higher volatility of 24.83% compared to OPKO Health, Inc. (OPK) at 12.14%. This indicates that ACON's price experiences larger fluctuations and is considered to be riskier than OPK based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ACON	OPK	Difference
Volatility (1M) Calculated over the trailing 1-month period	24.83%	12.14%	+12.69%
Volatility (6M) Calculated over the trailing 6-month period	87.31%	24.43%	+62.88%
Volatility (1Y) Calculated over the trailing 1-year period	99.60%	37.89%	+61.71%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	176.46%	56.60%	+119.86%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	176.46%	64.67%	+111.79%

Financials