T2 Biosystems, Inc. (TTOO)

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T2 Biosystems, Inc. (TTOO) is down 90.0% since the beginning of the year. At $0 per share, TTOO is trading 99.4% below its 52-week high of $0. Investors who bought $1,000 worth of TTOO shares 5 years ago would now be looking at an investment worth $0.

T2 Biosystems, Inc. (TTOO) has returned -90.00% so far this year and -99.38% over the past 12 months. Over the last ten years, TTOO has returned -73.61% per year, falling short of the S&P 500 Index benchmark, which averaged 13.26% annually.

Based on dividend-adjusted daily data since Aug 7, 2014, TTOO's average daily return is +3.01%, while the average monthly return is +19.28%. At this rate, an investment would double in approximately 0.3 years.

Historically, 35% of months were positive and 65% were negative. The best month was Oct 2023 with a return of +2,575.4%, while the worst month was Jul 2025 at -87.1%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 10 months.

On a daily basis, TTOO closed higher 41% of trading days. The best single day was Oct 13, 2023 with a return of +4,612.6%, while the worst single day was Apr 17, 2026 at -90.0%.

T2 Biosystems, Inc. has an annualized alpha of 174686.16%, beta of 0.14, and R2 of 0.00 versus S&P 500 Index. Calculated based on daily prices since August 07, 2014.

• This stock participated in 179.98% of S&P 500 Index downside but only -147.96% of its upside - more exposed to losses than it benefited from rallies.
• Beta of 0.14 may look defensive, but with R2 of 0.00 this stock is largely uncorrelated with S&P 500 Index - low beta reflects independence, not downside protection. See the Volatility section for a true picture of this stock's risk.
• R2 of 0.00 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

TTOO ranks 53 for risk / return — above 53% of stocks peers on PortfoliosLab. Its historical combined result is near the middle of the peer group.

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the T2 Biosystems, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the T2 Biosystems, Inc. was 100.00%, occurring on Mar 30, 2026. The portfolio has not yet recovered.

The current T2 Biosystems, Inc. drawdown is 100.00%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of T2 Biosystems, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how T2 Biosystems, Inc. is priced in the market compared to other companies in the Diagnostics & Research industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.