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ISIN
US6402681083
CUSIP
640268108
IPO Date
May 3, 1994

Highlights

Market Cap
$1.63B
Enterprise Value
$1.58B
EPS (TTM)
-$8.64
Total Revenue (TTM)
$55.63M
Gross Profit (TTM)
$44.58M
EBITDA (TTM)
-$121.05M
Year Range
$21.02 - $109.00
Target Price
$132.83
ROA (TTM)
-20.71%
ROE (TTM)
-27.44%

Share Price Chart


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Performance

NKTR Performance Chart

Nektar Therapeutics (NKTR) is up 55.4% since the beginning of the year. At $66 per share, NKTR is trading 39.7% below its 52-week high of $109. Investors who bought $1,000 worth of NKTR shares 5 years ago would now be looking at an investment worth $263.


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S&P 500 Index

Returns By Period

Nektar Therapeutics (NKTR) has returned 55.39% so far this year and 672.03% over the past 12 months. Over the last ten years, NKTR has returned -11.21% per year, falling short of the S&P 500 Index benchmark, which averaged 13.88% annually.


Nektar Therapeutics

1D
7.74%
1M
-1.37%
YTD
55.39%
6M
51.10%
1Y
672.03%
3Y*
96.12%
5Y*
-23.46%
10Y*
-11.21%

Benchmark (S&P 500 Index)

1D
-0.37%
1M
-0.01%
YTD
9.16%
6M
8.15%
1Y
24.03%
3Y*
19.78%
5Y*
11.99%
10Y*
13.88%
*Multi-year figures are annualized to reflect compound growth (CAGR)

NKTR Monthly Returns History

Based on dividend-adjusted daily data since May 3, 1994, NKTR's average daily return is +0.11%, while the average monthly return is +2.08%. At this rate, an investment would double in approximately 2.8 years.

Historically, 48% of months were positive and 52% were negative. The best month was Jun 2025 with a return of +137.8%, while the worst month was Feb 2023 at -49.3%. The longest winning streak lasted 8 consecutive months, and the longest losing streak was 6 months.

On a daily basis, NKTR closed higher 46% of trading days. The best single day was Jun 24, 2025 with a return of +156.3%, while the worst single day was Mar 14, 2022 at -60.9%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-11.71%84.78%4.31%18.19%-23.71%1.26%55.39%
2025-11.04%1.54%-19.05%16.99%-8.93%137.77%-16.10%37.73%90.56%14.11%0.43%-35.16%203.08%
2024-4.02%30.92%31.58%56.28%-13.01%-2.36%8.06%-4.48%1.56%-8.46%-4.20%-18.42%64.60%
202320.35%-49.26%-49.07%7.03%-22.89%-0.84%-6.85%11.05%0.10%-21.26%4.48%15.31%-75.00%
2022-17.69%-7.91%-47.36%-23.38%-15.74%9.20%4.21%-0.51%-18.78%17.50%-25.53%-19.29%-83.27%
202115.88%15.18%-11.86%-1.95%-7.85%-5.04%-7.98%-1.96%16.02%-15.59%-25.73%19.98%-20.53%

Benchmark Metrics

Nektar Therapeutics has an annualized alpha of 14.28%, beta of 1.31, and R2 of 0.10 versus S&P 500 Index. Calculated based on daily prices since May 03, 1994.

  • This stock participated in 138.37% of S&P 500 Index downside but only 103.49% of its upside - more exposed to losses than it benefited from rallies.
  • R2 of 0.10 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
14.28%
Beta
1.31
0.10
Upside Capture
103.49%
Downside Capture
138.37%

Return for Risk

Risk / Return Rank

NKTR ranks 98 for risk / return — in the top 98% of stocks on our site. This means strong returns relative to risk — exactly what professional investors look for. Well-suited for investors who want to maximize return per unit of risk.


NKTR Risk / Return Rank: 9898
Overall Rank
NKTR Sharpe Ratio Rank: 9797
Sharpe Ratio Rank
NKTR Sortino Ratio Rank: 9999
Sortino Ratio Rank
NKTR Omega Ratio Rank: 9898
Omega Ratio Rank
NKTR Calmar Ratio Rank: 9999
Calmar Ratio Rank
NKTR Martin Ratio Rank: 9898
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Nektar Therapeutics (NKTR) and compare them to S&P 500 Index.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


NKTRBenchmarkDifference
Sharpe ratioReturn per unit of total volatility

+1.71

Sortino ratioReturn per unit of downside risk

+4.07

Omega ratioGain probability vs. loss probability

1.77

1.37

+0.40

Calmar ratioReturn relative to maximum drawdown

14.58

2.78

+11.79

Martin ratioReturn relative to average drawdown

31.29

12.44

+18.85

Dividends

Dividend History


Nektar Therapeutics doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Nektar Therapeutics. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Nektar Therapeutics was 99.61%, occurring on Nov 28, 2023. The portfolio has not yet recovered.

The current Nektar Therapeutics drawdown is 95.96%.


Related event

Drawdown

Fall

Recovery

Underwater

2023 bear market2023
-99.61%Nov 2023
5y 8mo
8y 3moMar 2018 - now
Financial crisis2007–2009
-95.53%Oct 2008
8y 7mo9y 2mo
17y 10moMar 2000 - Jan 2018
1998 bear market1998
-41.10%Oct 1998
12mo 3d1y 2mo
2y 2moOct 1997 - Dec 1999
1996 bear market1996
-38.17%Sep 1996
4mo 14d5mo 23d
10mo 7dMay 1996 - Mar 1997
1995 bear market1995
-37.78%Apr 1995
5mo 26d4mo 7d
10mo 3dOct 1994 - Aug 1995

Drawdown Indicators


NKTRBenchmarkDifference

Max Drawdown

Largest peak-to-trough decline

-99.61%

-56.78%

-42.83%

Max Drawdown (1Y)

Largest decline over 1 year

-46.54%

-9.10%

-37.44%

Max Drawdown (3Y)

Largest decline over 3 years

-73.20%

-18.90%

-54.30%

Max Drawdown (5Y)

Largest decline over 5 years

-97.76%

-25.43%

-72.33%

Max Drawdown (10Y)

Largest decline over 10 years

-99.61%

-33.92%

-65.69%

Current Drawdown

Current decline from peak

-95.96%

-1.80%

-94.16%

Average Drawdown

Average peak-to-trough decline

-68.35%

-10.71%

-57.64%

Ulcer Index

Depth and duration of drawdowns from previous peaks

21.64%

2.03%

+19.61%

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Nektar Therapeutics over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Nektar Therapeutics is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for NKTR relative to other companies in the Biotechnology industry. Currently, NKTR has a P/S ratio of 21.6. This P/S ratio falls within the average range for the industry, suggesting the stock is fairly valued based on its revenue.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for NKTR in comparison with other companies in the Biotechnology industry. Currently, NKTR has a P/B value of 2.8. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items
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