Highlights
- Market Cap
- $5.18M
- Enterprise Value
- -$18.34M
- EPS (TTM)
- -$6.53
- Gross Profit (TTM)
- -$68.10K
- EBITDA (TTM)
- -$20.59M
- Year Range
- $1.33 - $250.00
- ROA (TTM)
- -98.45%
- ROE (TTM)
- -120.74%
Share Price Chart
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Performance
Performance Chart
The chart shows the growth of an initial investment of $10,000 in NuCana plc, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.
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Returns By Period
NuCana plc (NCNA) has returned -61.11% so far this year and -99.20% over the past 12 months.
NuCana plc
- 1D
- 4.48%
- 1M
- -35.19%
- YTD
- -61.11%
- 6M
- -69.83%
- 1Y
- -99.20%
- 3Y*
- -93.37%
- 5Y*
- -85.91%
- 10Y*
- —
Benchmark (S&P 500 Index)
- 1D
- 2.91%
- 1M
- -5.09%
- YTD
- -4.63%
- 6M
- -2.39%
- 1Y
- 16.33%
- 3Y*
- 16.69%
- 5Y*
- 10.18%
- 10Y*
- 12.16%
Monthly Returns
Based on dividend-adjusted daily data since Sep 28, 2017, NCNA's average daily return is -0.13%, while the average monthly return is -4.34%.
Historically, 28% of months were positive and 72% were negative. The best month was Jul 2022 with a return of +153.8%, while the worst month was May 2025 at -94.0%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 11 months.
On a daily basis, NCNA closed higher 42% of trading days. The best single day was Aug 19, 2024 with a return of +177.1%, while the worst single day was May 8, 2025 at -65.8%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -30.28% | -13.94% | -35.19% | -61.11% | |||||||||
| 2025 | -14.29% | -4.90% | -10.02% | -32.40% | -94.02% | 62.61% | -25.26% | -62.82% | 45.45% | -13.58% | 6.73% | -15.89% | -98.49% |
| 2024 | 1.39% | 6.70% | -18.75% | -39.08% | -8.84% | -29.36% | 42.75% | 0.55% | -37.16% | -29.57% | -19.75% | -8.46% | -83.91% |
| 2023 | 128.79% | -3.97% | -33.79% | -11.57% | -1.71% | -5.33% | -3.80% | -5.26% | -15.28% | -19.67% | -15.71% | -28.38% | -55.18% |
| 2022 | 19.75% | -5.26% | -63.00% | -29.63% | -16.37% | 23.32% | 153.79% | -21.20% | -27.93% | -4.31% | -14.61% | -22.71% | -72.27% |
| 2021 | 28.73% | -8.65% | -5.49% | -13.03% | -29.49% | -9.48% | -23.47% | 25.47% | -3.01% | -6.20% | 12.81% | -12.82% | -46.99% |
Benchmark Metrics
NuCana plc has an annualized alpha of -36.60%, beta of 1.02, and R² of 0.02 versus S&P 500 Index. Calculated based on daily prices since September 29, 2017.
- This stock participated in 194.69% of S&P 500 Index downside but only -127.76% of its upside — more exposed to losses than it benefited from rallies.
- R² of 0.02 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- -36.60%
- Beta
- 1.02
- R²
- 0.02
- Upside Capture
- -127.76%
- Downside Capture
- 194.69%
Return for Risk
Risk / Return Rank
NCNA ranks 12 for risk / return — in the bottom 12% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.
Return / Risk — by metrics
The table below present risk-adjusted performance metrics for NuCana plc (NCNA) and compare them to a chosen benchmark (S&P 500 Index).
| NCNA | Benchmark | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | -0.39 | 0.90 | -1.28 |
Sortino ratioReturn per unit of downside risk | -1.14 | 1.39 | -2.52 |
Omega ratioGain probability vs. loss probability | 0.84 | 1.21 | -0.37 |
Calmar ratioReturn relative to maximum drawdown | -1.00 | 1.40 | -2.40 |
Martin ratioReturn relative to average drawdown | -1.08 | 6.61 | -7.68 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
Explore NCNA risk-adjusted metrics in detail
Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.
Dividends
Dividend History
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the NuCana plc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the NuCana plc was 100.00%, occurring on Mar 30, 2026. The portfolio has not yet recovered.
The current NuCana plc drawdown is 100.00%.
Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -100% | Jun 7, 2018 | 1963 | Mar 30, 2026 | — | — | — |
| -46.58% | Oct 5, 2017 | 59 | Dec 28, 2017 | 14 | Jan 19, 2018 | 73 |
| -38.3% | Jan 29, 2018 | 38 | Mar 22, 2018 | 12 | Apr 10, 2018 | 50 |
| -25.39% | Apr 11, 2018 | 21 | May 9, 2018 | 19 | Jun 6, 2018 | 40 |
| -1.74% | Oct 2, 2017 | 1 | Oct 2, 2017 | 1 | Oct 3, 2017 | 2 |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Financials
Financial Performance
The chart below illustrates the trends in the financial health of NuCana plc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.
Valuation
The Valuation section provides an overview of how NuCana plc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.
PB Ratio
The chart illustrates the Price-to-Book (P/B) ratio for NCNA in comparison with other companies in the Biotechnology industry. Currently, NCNA has a P/B value of 0.2. This P/B ratio is low compared to industry peers. It might indicate the stock is undervalued or that the company’s assets are not expected to generate strong returns.
Income Statement
| TTM | |
|---|---|
Revenue | — |
Total Revenue | — |
Cost Of Revenue | — |
Gross Profit | — |
Operating Expenses | — |
Selling, General & Admin Expenses | — |
R&D Expenses | — |
Depreciation And Amortization | — |
Total Operating Expenses | — |
Income | — |
Income Before Tax | — |
Operating Income | — |
EBITDA | — |
EBIT | — |
Earnings From Continuing Operations | — |
Net Income | — |
Income Tax Expense | — |
Other Non-Operating Income (Expenses) | — |
Extraordinary Items | — |
Discontinued Operations | — |
Effect Of Accounting Charges | — |
Non Recurring | — |
Minority Interest | — |
Other Items | — |
Interest Income | — |
Interest Expense | — |
Net Interest Income | — |