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Ensysce Biosciences Inc (ENSC)
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN
US2936021086
CUSIP
29357R108
IPO Date
Feb 26, 2018

Highlights

EPS (TTM)
-$6.00M
Total Revenue (TTM)
$3.18M
Gross Profit (TTM)
-$1.69M
EBITDA (TTM)
-$4.71M
Year Range
$0.31 - $4.85
ROA (TTM)
-136.54%
ROE (TTM)
-316.63%

Share Price Chart


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Ensysce Biosciences Inc

Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Ensysce Biosciences Inc, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


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S&P 500 Index

Returns By Period

Ensysce Biosciences Inc (ENSC) has returned -41.47% so far this year and -78.96% over the past 12 months.


Ensysce Biosciences Inc

1D
4.77%
1M
-13.59%
YTD
-41.47%
6M
-77.28%
1Y
-78.96%
3Y*
-80.52%
5Y*
-89.69%
10Y*

Benchmark (S&P 500 Index)

1D
2.91%
1M
-5.09%
YTD
-4.63%
6M
-2.39%
1Y
16.33%
3Y*
16.69%
5Y*
10.18%
10Y*
12.16%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Feb 26, 2018, ENSC's average daily return is -0.23%, while the average monthly return is -6.15%.

Historically, 42% of months were positive and 58% were negative. The best month was Dec 2021 with a return of +197.5%, while the worst month was Dec 2022 at -74.1%. The longest winning streak lasted 10 consecutive months, and the longest losing streak was 12 months.

On a daily basis, ENSC closed higher 34% of trading days. The best single day was Oct 22, 2024 with a return of +161.7%, while the worst single day was Dec 7, 2022 at -53.4%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-21.07%-14.18%-13.59%-41.47%
2025-15.57%-21.57%-52.50%17.97%-26.49%0.45%-6.28%0.00%13.40%-8.02%-18.81%-48.02%-88.70%
202452.83%-42.44%-15.25%-25.13%-2.81%-11.91%-11.15%-12.22%-39.24%140.00%-14.24%9.85%-48.81%
2023-6.67%-30.14%-17.18%-22.84%-36.80%-24.05%12.50%-8.64%-25.41%-33.25%23.77%-7.02%-88.22%
2022-62.98%-35.63%1.79%-3.51%-49.03%54.88%-40.71%-17.96%-49.10%-24.88%-10.22%-74.14%-99.20%
20210.04%13.26%-7.17%-2.68%8.80%4.62%-61.01%-44.07%-4.11%-27.39%-28.18%197.47%-62.20%

Benchmark Metrics

Ensysce Biosciences Inc has an annualized alpha of -47.40%, beta of 0.53, and R² of 0.01 versus S&P 500 Index. Calculated based on daily prices since March 12, 2018.

  • This stock participated in 211.77% of S&P 500 Index downside but only -115.19% of its upside — more exposed to losses than it benefited from rallies.
  • Beta of 0.53 may look defensive, but with R² of 0.01 this stock is largely uncorrelated with S&P 500 Index — low beta reflects independence, not downside protection. See the Volatility section for a true picture of this stock's risk.
  • R² of 0.01 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
-47.40%
Beta
0.53
0.01
Upside Capture
-115.19%
Downside Capture
211.77%

Return for Risk

Risk / Return Rank

ENSC ranks 12 for risk / return — in the bottom 12% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.


ENSC Risk / Return Rank: 1212
Overall Rank
ENSC Sharpe Ratio Rank: 1818
Sharpe Ratio Rank
ENSC Sortino Ratio Rank: 1313
Sortino Ratio Rank
ENSC Omega Ratio Rank: 1414
Omega Ratio Rank
ENSC Calmar Ratio Rank: 66
Calmar Ratio Rank
ENSC Martin Ratio Rank: 99
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics

The table below present risk-adjusted performance metrics for Ensysce Biosciences Inc (ENSC) and compare them to a chosen benchmark (S&P 500 Index).


ENSCBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

-0.53

0.90

-1.42

Sortino ratio

Return per unit of downside risk

-0.86

1.39

-2.24

Omega ratio

Gain probability vs. loss probability

0.90

1.21

-0.31

Calmar ratio

Return relative to maximum drawdown

-0.93

1.40

-2.33

Martin ratio

Return relative to average drawdown

-1.51

6.61

-8.12

Explore ENSC risk-adjusted metrics in detail

Dive deeper into individual metrics with historical trends, benchmark comparisons, and performance across different time periods.

Dividends

Dividend History


Ensysce Biosciences Inc doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the Ensysce Biosciences Inc. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Ensysce Biosciences Inc was 100.00%, occurring on Feb 23, 2026. The portfolio has not yet recovered.

The current Ensysce Biosciences Inc drawdown is 100.00%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-100%Feb 2, 20211270Feb 23, 2026
-19.69%Jun 19, 2020101Nov 10, 202030Dec 23, 2020131
-11.79%Dec 28, 20208Jan 7, 202116Feb 1, 202124
-6.64%May 19, 20205May 26, 202016Jun 17, 202021
-5.5%Apr 6, 202028May 14, 20202May 18, 202030

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Financials

Financial Performance

The chart below illustrates the trends in the financial health of Ensysce Biosciences Inc over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Valuation

The Valuation section provides an overview of how Ensysce Biosciences Inc is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for ENSC relative to other companies in the Biotechnology industry. Currently, ENSC has a P/S ratio of 0.3. This P/S ratio is low compared to the industry average. It may indicate that the stock is undervalued relative to its revenue, or that the market expects slower growth or lower margins.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items