Codexis, Inc. (CDXS)

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The chart shows the growth of an initial investment of $10,000 in Codexis, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.

Codexis, Inc. (CDXS) has returned -0.00% so far this year and -39.41% over the past 12 months. Over the last ten years, CDXS has returned -6.49% per year, falling short of the S&P 500 Index benchmark, which averaged 12.16% annually.

Based on dividend-adjusted daily data since Apr 22, 2010, CDXS's average daily return is +0.04%, while the average monthly return is +0.66%. At this rate, your investment would double in approximately 8.8 years.

Historically, 48% of months were positive and 52% were negative. The best month was Feb 2024 with a return of +76.8%, while the worst month was Aug 2023 at -51.7%. The longest winning streak lasted 7 consecutive months, and the longest losing streak was 6 months.

On a daily basis, CDXS closed higher 46% of trading days. The best single day was Jul 15, 2014 with a return of +44.0%, while the worst single day was Jul 15, 2022 at -44.7%.

Codexis, Inc. has an annualized alpha of -6.50%, beta of 1.40, and R² of 0.12 versus S&P 500 Index. Calculated based on daily prices since April 23, 2010.

• This stock participated in 150.03% of S&P 500 Index downside but only 43.73% of its upside — more exposed to losses than it benefited from rallies.
• R² of 0.12 means this stock moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

CDXS ranks 21 for risk / return — below 21% of stocks on our site. The returns aren't fully compensating for the risk involved. This isn't necessarily a dealbreaker, but factor it into your decision — especially if you're risk-averse.

The table below present risk-adjusted performance metrics for Codexis, Inc. (CDXS) and compare them to a chosen benchmark (S&P 500 Index).

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Codexis, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Codexis, Inc. was 97.65%, occurring on Mar 3, 2026. The portfolio has not yet recovered.

The current Codexis, Inc. drawdown is 96.10%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Codexis, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Codexis, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.