Can-Fite BioPharma Ltd. (CANF)

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Can-Fite BioPharma Ltd. (CANF) is down 22.3% since the beginning of the year. At $3 per share, CANF is trading 86.7% below its 52-week high of $23. Investors who bought $1,000 worth of CANF shares 5 years ago would now be looking at an investment worth $7.

Can-Fite BioPharma Ltd. (CANF) has returned -22.25% so far this year and -85.80% over the past 12 months. Over the last ten years, CANF has returned -55.04% per year, falling short of the S&P 500 Index benchmark, which averaged 13.75% annually.

Based on dividend-adjusted daily data since Nov 6, 2012, CANF's average daily return is -0.10%, while the average monthly return is -2.99%.

Historically, 37% of months were positive and 63% were negative. The best month was Sep 2015 with a return of +133.9%, while the worst month was May 2019 at -61.4%. The longest winning streak lasted 3 consecutive months, and the longest losing streak was 10 months.

On a daily basis, CANF closed higher 40% of trading days. The best single day was Sep 17, 2015 with a return of +95.2%, while the worst single day was Mar 30, 2015 at -60.3%.

Can-Fite BioPharma Ltd. has an annualized alpha of -27.01%, beta of 0.41, and R2 of 0.01 versus S&P 500 Index. Calculated based on daily prices since November 07, 2012.

• This stock participated in 233.86% of S&P 500 Index downside but only -27.55% of its upside - more exposed to losses than it benefited from rallies.
• Beta of 0.41 may look defensive, but with R2 of 0.01 this stock is largely uncorrelated with S&P 500 Index - low beta reflects independence, not downside protection. See the Volatility section for a true picture of this stock's risk.
• R2 of 0.01 means this stock moves largely independently of S&P 500 Index - capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

CANF ranks 4 for risk / return — in the bottom 4% of stocks on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.

The table below present risk-adjusted performance metrics for Can-Fite BioPharma Ltd. (CANF) and compare them to S&P 500 Index.

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.

The table below displays the maximum drawdowns of the Can-Fite BioPharma Ltd.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Can-Fite BioPharma Ltd. was 99.99%, occurring on Apr 23, 2026. The portfolio has not yet recovered.

The current Can-Fite BioPharma Ltd. drawdown is 99.99%.

The chart below shows the rolling one-month volatility.

The chart below illustrates the trends in the financial health of Can-Fite BioPharma Ltd. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.

The Valuation section provides an overview of how Can-Fite BioPharma Ltd. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.