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Annovis Bio, Inc. (ANVS)
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility
Financials

Company Info

ISIN

US03615A1088

CUSIP

03615A108

IPO Date

Feb 12, 2010

Highlights

Market Cap

$30.20M

EPS (TTM)

-$2.31

EBITDA (TTM)

-$18.89M

Year Range

$1.11 - $17.88

Target Price

$31.20

Short %

10.46%

Short Ratio

6.93

Share Price Chart


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Compare to other instruments

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Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in Annovis Bio, Inc., comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends.


-100.00%-50.00%0.00%50.00%100.00%December2025FebruaryMarchAprilMay
-83.32%
73.03%
ANVS (Annovis Bio, Inc.)
Benchmark (^GSPC)

Returns By Period

Annovis Bio, Inc. (ANVS) returned -68.19% year-to-date (YTD) and -66.80% over the past 12 months.


ANVS

YTD

-68.19%

1M

31.15%

6M

-81.42%

1Y

-66.80%

5Y*

-14.73%

10Y*

N/A

^GSPC (Benchmark)

YTD

-3.70%

1M

13.67%

6M

-5.18%

1Y

9.18%

5Y*

14.14%

10Y*

10.43%

*Annualized

Monthly Returns

The table below presents the monthly returns of ANVS, with color gradation from worst to best to easily spot seasonal factors. Returns are adjusted for dividends.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2025-3.18%-62.42%-18.03%-0.67%7.38%-68.19%
2024-40.91%-23.35%40.50%-53.19%17.59%-12.06%61.63%-9.13%-4.73%15.14%-27.69%-25.04%-73.10%
202323.01%3.57%-9.94%-5.45%-10.09%9.08%-3.50%-10.08%-23.47%-30.35%28.44%120.26%39.24%
2022-13.71%-6.39%-5.99%-29.29%-2.75%23.53%1.41%0.87%18.10%-8.39%7.09%-0.07%-23.61%
202132.36%156.21%9.11%-20.65%103.70%89.76%-59.77%9.61%-15.87%-16.47%-9.28%-26.93%133.16%
2020-32.01%-25.61%-38.14%28.33%15.32%-2.02%33.33%-18.10%1.26%-5.20%19.52%38.35%-21.38%

Risk-Adjusted Performance

Risk-Adjusted Performance Rank

The current rank of ANVS is 20, meaning it’s performing worse than 80% of other stocks on our website when it comes to balancing risk and reward. Below is a breakdown of how it compares using common performance measures.


The Risk-Adjusted Performance Rank of ANVS is 2020
Overall Rank
The Sharpe Ratio Rank of ANVS is 2424
Sharpe Ratio Rank
The Sortino Ratio Rank of ANVS is 2121
Sortino Ratio Rank
The Omega Ratio Rank of ANVS is 2424
Omega Ratio Rank
The Calmar Ratio Rank of ANVS is 99
Calmar Ratio Rank
The Martin Ratio Rank of ANVS is 2121
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

Risk-Adjusted Performance Indicators

The charts below present risk-adjusted performance metrics for Annovis Bio, Inc. (ANVS) and compare them to a chosen benchmark (^GSPC). These indicators evaluate an investment's returns against its associated risks.


The current Annovis Bio, Inc. Sharpe ratio is -0.50. This value is calculated based on the past 1 year of trading data and takes into account price changes and dividends.

Use the chart below to compare the Sharpe ratio of Annovis Bio, Inc. with the selected benchmark, providing insights into the investment's historical performance in terms of risk-adjusted returns. Go to the Sharpe ratio tool for more fine-grained control over the calculation options.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.00December2025FebruaryMarchAprilMay
-0.50
0.48
ANVS (Annovis Bio, Inc.)
Benchmark (^GSPC)

Dividends

Dividend History


Annovis Bio, Inc. doesn't pay dividends

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


-100.00%-80.00%-60.00%-40.00%-20.00%0.00%December2025FebruaryMarchAprilMay
-98.68%
-7.82%
ANVS (Annovis Bio, Inc.)
Benchmark (^GSPC)

Worst Drawdowns

The table below displays the maximum drawdowns of the Annovis Bio, Inc.. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the Annovis Bio, Inc. was 98.99%, occurring on Apr 8, 2025. The portfolio has not yet recovered.

The current Annovis Bio, Inc. drawdown is 98.68%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-98.99%Jul 14, 2021939Apr 8, 2025
-73.93%Jan 30, 202045Apr 2, 2020197Jan 13, 2021242
-43.94%Mar 18, 202133May 4, 202113May 21, 202146
-25.67%May 24, 20214May 27, 20214Jun 3, 20218
-25.05%Feb 23, 20219Mar 5, 20216Mar 15, 202115

Volatility

Volatility Chart

The current Annovis Bio, Inc. volatility is 23.72%, representing the average percentage change in the investments's value, either up or down over the past month. The chart below shows the rolling one-month volatility.


0.00%10.00%20.00%30.00%40.00%December2025FebruaryMarchAprilMay
23.72%
11.21%
ANVS (Annovis Bio, Inc.)
Benchmark (^GSPC)

Financials

Financial Performance

The chart below illustrates the trends in the financial health of Annovis Bio, Inc. over time, highlighting three key metrics: Total Revenue, Earnings Before Interest and Taxes (EBIT), and Net Income.


Annual
Quarterly

0.0

Earnings Per Share

The chart presents the Earnings Per Share (EPS) performance of Annovis Bio, Inc., comparing actual results with analytics estimates. In the past quarter, the company did not meet analyst expectations for EPS, resulting in a surprise of -115.0%.


-2.00-1.50-1.00-0.500.0020212022202320242025
-0.43
-0.80
Actual
Estimate

Valuation

The Valuation section provides an overview of how Annovis Bio, Inc. is priced in the market compared to other companies in the Biotechnology industry. It includes key financial ratios that help investors assess whether the stock is undervalued or overvalued.


PS Ratio

This chart shows the Price-to-Sales (P/S) ratio for ANVS relative to other companies in the Biotechnology industry. Currently, ANVS has a P/S ratio of 0.0. This P/S ratio is low compared to the industry average. It may indicate that the stock is undervalued relative to its revenue, or that the market expects slower growth or lower margins.

PB Ratio

The chart illustrates the Price-to-Book (P/B) ratio for ANVS in comparison with other companies in the Biotechnology industry. Currently, ANVS has a P/B value of 3.4. This P/B ratio is in line with the industry average, suggesting the stock is valued fairly in relation to its book value.

Income Statement



TTM
Revenue

Total Revenue

Cost Of Revenue

Gross Profit

Operating Expenses

Selling, General & Admin Expenses

R&D Expenses

Depreciation And Amortization

Total Operating Expenses

Income

Income Before Tax

Operating Income

EBITDA

EBIT

Earnings From Continuing Operations

Net Income

Income Tax Expense

Other Non-Operating Income (Expenses)

Extraordinary Items

Discontinued Operations

Effect Of Accounting Charges

Non Recurring

Minority Interest

Other Items

Interest Income

Interest Expense

Net Interest Income

Values in undefined except per share items