Asset Allocation
| Position | Category/Sector | Target Weight |
|---|---|---|
ABCL AbCellera Biologics Inc. | Healthcare | 20% |
EXAI Exscientia Ltd ADR | Healthcare | 20% |
IBB iShares Nasdaq Biotechnology ETF | Health & Biotech Equities | 20% |
RXRX Recursion Pharmaceuticals, Inc. | Healthcare | 20% |
SDGR Schrodinger, Inc. | Healthcare | 20% |
Performance
Performance Chart
The chart shows the growth of an initial investment of $10,000 in AI biotechs vs IBB, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends. The portfolio is rebalanced Every 3 months.
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The earliest data available for this chart is Oct 1, 2021, corresponding to the inception date of EXAI
Returns By Period
| 1D | 1M | YTD | 6M | 1Y | 3Y* | 5Y* | 10Y* | |
|---|---|---|---|---|---|---|---|---|
Benchmark S&P 500 Index | 0.62% | 0.64% | -0.30% | 1.33% | 25.06% | 18.43% | 10.57% | 12.82% |
Portfolio AI biotechs vs IBB | -0.49% | -2.46% | -10.07% | -24.80% | 5.62% | -7.81% | — | — |
| Portfolio components: | ||||||||
IBB iShares Nasdaq Biotechnology ETF | 0.17% | 0.01% | 2.08% | 13.43% | 45.47% | 10.02% | 3.24% | 6.87% |
RXRX Recursion Pharmaceuticals, Inc. | -2.36% | -3.78% | -19.07% | -43.99% | -28.82% | -20.23% | — | — |
EXAI Exscientia Ltd ADR | — | — | — | — | — | — | — | — |
ABCL AbCellera Biologics Inc. | 0.29% | -3.64% | 0.58% | -41.79% | 58.53% | -21.82% | -34.42% | — |
SDGR Schrodinger, Inc. | -0.26% | -9.18% | -35.85% | -44.46% | -41.24% | -25.15% | -31.11% | — |
Monthly Returns
Based on dividend-adjusted daily data since Oct 4, 2021, AI biotechs vs IBB's average daily return is -0.04%, while the average monthly return is -1.20%.
Historically, 42% of months were positive and 58% were negative. The best month was Jul 2023 with a return of +33.3%, while the worst month was Aug 2023 at -28.3%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 5 months.
On a daily basis, AI biotechs vs IBB closed higher 47% of trading days. The best single day was Jul 12, 2023 with a return of +19.7%, while the worst single day was Feb 13, 2024 at -10.3%.
| Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec | Total | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026 | -2.32% | -4.50% | -5.40% | 1.91% | -10.07% | ||||||||
| 2025 | 10.11% | -5.86% | -12.74% | 10.34% | -13.77% | 16.21% | 10.64% | -5.96% | 6.58% | 7.76% | -11.54% | -4.03% | 1.45% |
| 2024 | -10.25% | 11.25% | -10.51% | -13.73% | 1.86% | -8.57% | 9.26% | -6.90% | -7.00% | -1.64% | 10.06% | -6.00% | -30.89% |
| 2023 | 15.66% | -9.25% | -5.05% | -5.70% | 26.04% | 0.46% | 33.26% | -28.30% | -15.60% | -10.60% | 19.87% | 18.29% | 21.62% |
| 2022 | -21.81% | 0.71% | -6.66% | -19.62% | 2.18% | 13.27% | 2.02% | 2.95% | -5.91% | 2.03% | -6.70% | -10.16% | -42.21% |
| 2021 | -7.53% | -8.19% | -6.81% | -20.88% |
Benchmark Metrics
AI biotechs vs IBB has an annualized alpha of -24.75%, beta of 1.49, and R² of 0.28 versus S&P 500 Index. Calculated based on daily prices since October 04, 2021.
- This portfolio participated in 169.27% of S&P 500 Index downside but only 48.96% of its upside — more exposed to losses than it benefited from rallies.
- R² of 0.28 means this portfolio moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.
- Alpha
- -24.75%
- Beta
- 1.49
- R²
- 0.28
- Upside Capture
- 48.96%
- Downside Capture
- 169.27%
Expense Ratio
AI biotechs vs IBB has an expense ratio of 0.09%, which is considered low. Below, you can find the expense ratios of the portfolio's funds side by side and easily compare their relative costs.
Return for Risk
Risk / Return Rank
AI biotechs vs IBB ranks 4 for risk / return — in the bottom 4% of portfolios on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.
Return / Risk — by metrics
| Portfolio | Benchmark | Difference | |
|---|---|---|---|
Sharpe ratioReturn per unit of total volatility | 0.15 | 1.84 | -1.69 |
Sortino ratioReturn per unit of downside risk | 0.53 | 2.53 | -2.00 |
Omega ratioGain probability vs. loss probability | 1.06 | 1.35 | -0.29 |
Calmar ratioReturn relative to maximum drawdown | 0.33 | 3.83 | -3.49 |
Martin ratioReturn relative to average drawdown | 0.68 | 16.98 | -16.30 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
How much return does each position deliver for the risk it carries? Higher values mean better reward for the risk taken.
| Risk / Return Rank | Sharpe ratio | Sortino ratio | Omega ratio | Calmar ratio | Martin ratio | |
|---|---|---|---|---|---|---|
IBB iShares Nasdaq Biotechnology ETF | 60 | 2.08 | 2.79 | 1.36 | 5.03 | 17.03 |
RXRX Recursion Pharmaceuticals, Inc. | 21 | -0.36 | -0.05 | 0.99 | -0.36 | -0.70 |
EXAI Exscientia Ltd ADR | — | — | — | — | — | — |
ABCL AbCellera Biologics Inc. | 55 | 0.77 | 1.64 | 1.19 | 1.23 | 2.37 |
SDGR Schrodinger, Inc. | 10 | -0.71 | -0.94 | 0.89 | -0.63 | -1.12 |
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Dividends
Dividend yield
AI biotechs vs IBB provided a 0.05% dividend yield over the last twelve months.
| TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Portfolio | 0.05% | 0.05% | 0.06% | 0.05% | 0.06% | 0.04% | 0.04% | 0.07% | 0.04% | 0.06% | 0.04% | 0.01% |
| Portfolio components: | ||||||||||||
IBB iShares Nasdaq Biotechnology ETF | 0.23% | 0.23% | 0.29% | 0.26% | 0.31% | 0.21% | 0.21% | 0.33% | 0.20% | 0.30% | 0.19% | 0.03% |
RXRX Recursion Pharmaceuticals, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
EXAI Exscientia Ltd ADR | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
ABCL AbCellera Biologics Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
SDGR Schrodinger, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
Drawdowns
Drawdowns Chart
The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.
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Worst Drawdowns
The table below displays the maximum drawdowns of the AI biotechs vs IBB. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.
The maximum drawdown for the AI biotechs vs IBB was 69.31%, occurring on Apr 8, 2025. The portfolio has not yet recovered.
The current AI biotechs vs IBB drawdown is 64.94%.
Depth | Start | To Bottom | Bottom | To Recover | End | Total |
|---|---|---|---|---|---|---|
| -69.31% | Oct 4, 2021 | 882 | Apr 8, 2025 | — | — | — |
Volatility
Volatility Chart
The chart below shows the rolling one-month volatility.
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Diversification
Diversification Metrics
Number of Effective Assets
The portfolio contains 5 assets, with an effective number of assets of 5.00, reflecting the diversification based on asset allocation. This number of effective assets suggests a highly concentrated portfolio, where a few assets dominate the allocation, potentially increasing the portfolio's risk due to lack of diversification.
Asset Correlations Table
| Benchmark | EXAI | ABCL | RXRX | SDGR | IBB | Portfolio | |
|---|---|---|---|---|---|---|---|
| Benchmark | 1.00 | 0.27 | 0.40 | 0.49 | 0.50 | 0.65 | 0.54 |
| EXAI | 0.27 | 1.00 | 0.30 | 0.38 | 0.39 | 0.35 | 0.64 |
| ABCL | 0.40 | 0.30 | 1.00 | 0.54 | 0.56 | 0.56 | 0.74 |
| RXRX | 0.49 | 0.38 | 0.54 | 1.00 | 0.59 | 0.60 | 0.83 |
| SDGR | 0.50 | 0.39 | 0.56 | 0.59 | 1.00 | 0.62 | 0.80 |
| IBB | 0.65 | 0.35 | 0.56 | 0.60 | 0.62 | 1.00 | 0.71 |
| Portfolio | 0.54 | 0.64 | 0.74 | 0.83 | 0.80 | 0.71 | 1.00 |