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AI biotechs vs IBB
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Diversification

Asset Allocation


IBB 20.00%RXRX 20.00%EXAI 20.00%ABCL 20.00%SDGR 20.00%EquityEquity

S&P 500 Index

Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in AI biotechs vs IBB, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends. The portfolio is rebalanced Every 3 months.


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The earliest data available for this chart is Oct 1, 2021, corresponding to the inception date of EXAI

Returns By Period


1D1MYTD6M1Y3Y*5Y*10Y*
Benchmark
S&P 500 Index
0.62%0.64%-0.30%1.33%25.06%18.43%10.57%12.82%
Portfolio
AI biotechs vs IBB
-0.49%-2.46%-10.07%-24.80%5.62%-7.81%
IBB
iShares Nasdaq Biotechnology ETF
0.17%0.01%2.08%13.43%45.47%10.02%3.24%6.87%
RXRX
Recursion Pharmaceuticals, Inc.
-2.36%-3.78%-19.07%-43.99%-28.82%-20.23%
EXAI
Exscientia Ltd ADR
ABCL
AbCellera Biologics Inc.
0.29%-3.64%0.58%-41.79%58.53%-21.82%-34.42%
SDGR
Schrodinger, Inc.
-0.26%-9.18%-35.85%-44.46%-41.24%-25.15%-31.11%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Oct 4, 2021, AI biotechs vs IBB's average daily return is -0.04%, while the average monthly return is -1.20%.

Historically, 42% of months were positive and 58% were negative. The best month was Jul 2023 with a return of +33.3%, while the worst month was Aug 2023 at -28.3%. The longest winning streak lasted 4 consecutive months, and the longest losing streak was 5 months.

On a daily basis, AI biotechs vs IBB closed higher 47% of trading days. The best single day was Jul 12, 2023 with a return of +19.7%, while the worst single day was Feb 13, 2024 at -10.3%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
2026-2.32%-4.50%-5.40%1.91%-10.07%
202510.11%-5.86%-12.74%10.34%-13.77%16.21%10.64%-5.96%6.58%7.76%-11.54%-4.03%1.45%
2024-10.25%11.25%-10.51%-13.73%1.86%-8.57%9.26%-6.90%-7.00%-1.64%10.06%-6.00%-30.89%
202315.66%-9.25%-5.05%-5.70%26.04%0.46%33.26%-28.30%-15.60%-10.60%19.87%18.29%21.62%
2022-21.81%0.71%-6.66%-19.62%2.18%13.27%2.02%2.95%-5.91%2.03%-6.70%-10.16%-42.21%
2021-7.53%-8.19%-6.81%-20.88%

Benchmark Metrics

AI biotechs vs IBB has an annualized alpha of -24.75%, beta of 1.49, and R² of 0.28 versus S&P 500 Index. Calculated based on daily prices since October 04, 2021.

  • This portfolio participated in 169.27% of S&P 500 Index downside but only 48.96% of its upside — more exposed to losses than it benefited from rallies.
  • R² of 0.28 means this portfolio moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
-24.75%
Beta
1.49
0.28
Upside Capture
48.96%
Downside Capture
169.27%

Expense Ratio

AI biotechs vs IBB has an expense ratio of 0.09%, which is considered low. Below, you can find the expense ratios of the portfolio's funds side by side and easily compare their relative costs.


Return for Risk

Risk / Return Rank

AI biotechs vs IBB ranks 4 for risk / return — in the bottom 4% of portfolios on our site. This means you're taking on significantly more risk than the returns justify. Consider whether the potential upside is worth the volatility, or explore alternatives with better risk / return profiles.


AI biotechs vs IBB Risk / Return Rank: 44
Overall Rank
AI biotechs vs IBB Sharpe Ratio Rank: 33
Sharpe Ratio Rank
AI biotechs vs IBB Sortino Ratio Rank: 33
Sortino Ratio Rank
AI biotechs vs IBB Omega Ratio Rank: 33
Omega Ratio Rank
AI biotechs vs IBB Calmar Ratio Rank: 55
Calmar Ratio Rank
AI biotechs vs IBB Martin Ratio Rank: 55
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics


PortfolioBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.15

1.84

-1.69

Sortino ratio

Return per unit of downside risk

0.53

2.53

-2.00

Omega ratio

Gain probability vs. loss probability

1.06

1.35

-0.29

Calmar ratio

Return relative to maximum drawdown

0.33

3.83

-3.49

Martin ratio

Return relative to average drawdown

0.68

16.98

-16.30


How much return does each position deliver for the risk it carries? Higher values mean better reward for the risk taken.

Risk / Return RankSharpe ratioSortino ratioOmega ratioCalmar ratioMartin ratio
IBB
iShares Nasdaq Biotechnology ETF
602.082.791.365.0317.03
RXRX
Recursion Pharmaceuticals, Inc.
21-0.36-0.050.99-0.36-0.70
EXAI
Exscientia Ltd ADR
ABCL
AbCellera Biologics Inc.
550.771.641.191.232.37
SDGR
Schrodinger, Inc.
10-0.71-0.940.89-0.63-1.12

Sharpe Ratio

The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

AI biotechs vs IBB Sharpe ratios as of Apr 10, 2026 (values are recalculated daily):

  • 1-Year: 0.15
  • All Time: -0.42

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

Compared to the broad market, where average Sharpe ratios range from 1.87 to 2.87, this portfolio's current Sharpe ratio places it in the bottom 25%. This suggests weaker risk-adjusted returns than most portfolios, possibly due to lower returns, higher volatility, or both. It may be worth reviewing the allocation. You can use the Portfolio Optimization tool to explore options for improving the Sharpe ratio.

The chart below shows the rolling Sharpe ratio of AI biotechs vs IBB compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time.


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Dividends

Dividend yield

AI biotechs vs IBB provided a 0.05% dividend yield over the last twelve months.


TTM20252024202320222021202020192018201720162015
Portfolio0.05%0.05%0.06%0.05%0.06%0.04%0.04%0.07%0.04%0.06%0.04%0.01%
IBB
iShares Nasdaq Biotechnology ETF
0.23%0.23%0.29%0.26%0.31%0.21%0.21%0.33%0.20%0.30%0.19%0.03%
RXRX
Recursion Pharmaceuticals, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
EXAI
Exscientia Ltd ADR
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
ABCL
AbCellera Biologics Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
SDGR
Schrodinger, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the AI biotechs vs IBB. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the AI biotechs vs IBB was 69.31%, occurring on Apr 8, 2025. The portfolio has not yet recovered.

The current AI biotechs vs IBB drawdown is 64.94%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-69.31%Oct 4, 2021882Apr 8, 2025

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Diversification

Diversification Metrics


Number of Effective Assets

The portfolio contains 5 assets, with an effective number of assets of 5.00, reflecting the diversification based on asset allocation. This number of effective assets suggests a highly concentrated portfolio, where a few assets dominate the allocation, potentially increasing the portfolio's risk due to lack of diversification.

Asset Correlations Table

The table below displays the correlation coefficients between the individual components of the portfolio, the entire portfolio, and the chosen benchmark.

BenchmarkEXAIABCLRXRXSDGRIBBPortfolio
Benchmark1.000.270.400.490.500.650.54
EXAI0.271.000.300.380.390.350.64
ABCL0.400.301.000.540.560.560.74
RXRX0.490.380.541.000.590.600.83
SDGR0.500.390.560.591.000.620.80
IBB0.650.350.560.600.621.000.71
Portfolio0.540.640.740.830.800.711.00
The correlation results are calculated based on daily price changes starting from Oct 4, 2021