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DRUGS
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Diversification

Asset Allocation


S&P 500 Index

Performance

Performance Chart

The chart shows the growth of an initial investment of $10,000 in DRUGS, comparing it to the performance of the S&P 500 index or another benchmark. All prices have been adjusted for splits and dividends. The portfolio is rebalanced Every 3 months.


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The earliest data available for this chart is Nov 14, 2024, corresponding to the inception date of MDCX

Returns By Period


1D1MYTD6M1Y3Y*5Y*10Y*
Benchmark
S&P 500 Index
0.11%-3.43%-3.84%-1.98%16.08%16.86%10.37%12.29%
Portfolio
DRUGS
0.68%-5.25%-2.67%-1.45%21.48%
LLY
Eli Lilly and Company
-1.98%-7.16%-12.80%14.47%15.19%39.72%39.64%31.19%
JNJ
Johnson & Johnson
-0.44%-1.50%18.06%32.21%60.80%19.22%11.44%11.41%
ABBV
AbbVie Inc.
-2.86%-10.70%-7.86%-10.37%5.19%13.21%18.43%18.22%
AZN
AstraZeneca PLC
1.37%0.86%12.99%24.18%44.83%15.99%18.18%16.94%
NVS
Novartis AG
-0.68%-3.33%15.12%21.19%43.29%22.68%16.63%11.80%
MRK
Merck & Co., Inc.
0.02%1.62%15.68%37.20%44.64%6.77%13.97%12.22%
AMGN
Amgen Inc.
-1.51%-7.71%7.04%18.64%17.39%16.07%10.31%11.72%
GILD
Gilead Sciences, Inc.
-0.42%-4.96%14.47%27.92%28.18%22.94%20.43%7.76%
NVO
Novo Nordisk A/S
1.37%4.40%-24.78%-34.84%-43.28%-20.60%3.97%5.03%
PFE
Pfizer Inc.
-0.81%6.55%15.64%8.20%22.98%-6.37%0.03%4.18%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Monthly Returns

Based on dividend-adjusted daily data since Nov 15, 2024, DRUGS's average daily return is +0.05%, while the average monthly return is +0.97%. At this rate, your investment would double in approximately 6.0 years.

Historically, 61% of months were positive and 39% were negative. The best month was Sep 2025 with a return of +7.9%, while the worst month was Mar 2026 at -8.5%. The longest winning streak lasted 6 consecutive months, and the longest losing streak was 3 months.

On a daily basis, DRUGS closed higher 53% of trading days. The best single day was Oct 1, 2025 with a return of +4.2%, while the worst single day was Apr 4, 2025 at -6.0%.


JanFebMarAprMayJunJulAugSepOctNovDecTotal
20261.26%3.74%-8.47%1.23%-2.67%
20254.31%4.59%-3.91%-3.18%-2.43%3.27%5.63%5.74%7.92%0.92%6.85%-2.86%29.14%
2024-1.08%-6.04%-7.05%

Benchmark Metrics

DRUGS has an annualized alpha of 8.85%, beta of 0.59, and R² of 0.23 versus S&P 500 Index. Calculated based on daily prices since November 15, 2024.

  • This portfolio captured 125.08% of S&P 500 Index gains and 101.20% of its losses — amplifying both gains and losses, but participating more in upside than downside.
  • Beta of 0.59 may look defensive, but with R² of 0.23 this portfolio is largely uncorrelated with S&P 500 Index — low beta reflects independence, not downside protection. See the Volatility section for a true picture of this portfolio's risk.
  • R² of 0.23 means this portfolio moves largely independently of S&P 500 Index — capture ratios reflect limited market correlation rather than active downside protection. Consider using a more representative benchmark.

Alpha
8.85%
Beta
0.59
0.23
Upside Capture
125.08%
Downside Capture
101.20%

Expense Ratio

DRUGS has an expense ratio of 0.00%, meaning no management fees are charged. Below, you can find the expense ratios of the portfolio's funds side by side and easily compare their relative costs.


The portfolio doesn't include any funds that charge management fees.

Return for Risk

Risk / Return Rank

DRUGS ranks 27 for risk / return — below 27% of portfolios on our site. The returns aren't fully compensating for the risk involved. This isn't necessarily a dealbreaker, but factor it into your decision — especially if you're risk-averse.


DRUGS Risk / Return Rank: 2727
Overall Rank
DRUGS Sharpe Ratio Rank: 2323
Sharpe Ratio Rank
DRUGS Sortino Ratio Rank: 2323
Sortino Ratio Rank
DRUGS Omega Ratio Rank: 1717
Omega Ratio Rank
DRUGS Calmar Ratio Rank: 4747
Calmar Ratio Rank
DRUGS Martin Ratio Rank: 2525
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

Return / Risk — by metrics


PortfolioBenchmarkDifference

Sharpe ratio

Return per unit of total volatility

0.94

0.88

+0.06

Sortino ratio

Return per unit of downside risk

1.44

1.37

+0.07

Omega ratio

Gain probability vs. loss probability

1.18

1.21

-0.03

Calmar ratio

Return relative to maximum drawdown

1.84

1.39

+0.45

Martin ratio

Return relative to average drawdown

5.37

6.43

-1.06


How much return does each position deliver for the risk it carries? Higher values mean better reward for the risk taken.

Risk / Return RankSharpe ratioSortino ratioOmega ratioCalmar ratioMartin ratio
LLY
Eli Lilly and Company
510.360.781.110.561.37
JNJ
Johnson & Johnson
973.514.771.647.4825.03
ABBV
AbbVie Inc.
430.190.441.060.280.62
AZN
AstraZeneca PLC
841.662.361.313.468.67
NVS
Novartis AG
882.012.621.354.1612.14
MRK
Merck & Co., Inc.
821.552.201.282.897.69
AMGN
Amgen Inc.
590.601.071.131.102.65
GILD
Gilead Sciences, Inc.
710.981.581.182.105.65
NVO
Novo Nordisk A/S
11-0.80-0.970.87-0.78-1.35
PFE
Pfizer Inc.
680.871.381.171.894.26

Sharpe Ratio

The Sharpe ratio helps investors understand how much return they're getting for the level of risk taken. A higher Sharpe ratio indicates better risk-adjusted performance, meaning more reward for each unit of risk.

DRUGS Sharpe ratios as of Apr 3, 2026 (values are recalculated daily):

  • 1-Year: 0.94
  • All Time: 0.56

These values reflect how efficiently the investment has delivered returns relative to its volatility over different time periods. All figures are annualized and based on daily total returns (including price changes and dividends).

Compared to the broad market, where average Sharpe ratios range from 0.98 to 1.66, this portfolio's current Sharpe ratio places it in the bottom 25%. This suggests weaker risk-adjusted returns than most portfolios, possibly due to lower returns, higher volatility, or both. It may be worth reviewing the allocation. You can use the Portfolio Optimization tool to explore options for improving the Sharpe ratio.

The chart below shows the rolling Sharpe ratio of DRUGS compared to the selected benchmark. This view highlights how the investment's risk-adjusted performance has changed over time.


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Dividends

Dividend yield

DRUGS provided a 2.34% dividend yield over the last twelve months.


TTM20252024202320222021202020192018201720162015
Portfolio2.34%2.43%2.61%2.45%2.15%2.22%2.24%2.09%2.23%2.10%2.37%2.04%
LLY
Eli Lilly and Company
0.67%0.56%0.67%0.78%1.07%1.23%1.75%1.96%1.94%2.46%2.77%2.37%
JNJ
Johnson & Johnson
2.14%2.48%3.40%3.00%2.52%2.45%2.53%2.57%2.74%2.38%2.73%2.87%
ABBV
AbbVie Inc.
3.18%2.87%3.49%3.82%3.49%3.84%4.41%4.83%3.89%2.65%3.64%3.41%
AZN
AstraZeneca PLC
2.62%1.70%2.27%2.15%2.12%2.35%2.80%2.81%3.69%3.95%5.01%4.06%
NVS
Novartis AG
3.10%2.90%3.84%3.44%3.70%3.86%3.22%3.03%3.47%3.24%3.73%3.10%
MRK
Merck & Co., Inc.
2.75%3.12%3.14%2.72%2.52%3.41%3.03%2.48%2.60%3.36%3.14%3.43%
AMGN
Amgen Inc.
2.78%2.91%3.45%2.96%2.95%3.13%2.78%2.41%2.71%2.65%2.74%1.95%
GILD
Gilead Sciences, Inc.
2.28%2.57%3.33%3.70%3.40%3.91%4.67%3.88%3.65%2.90%2.57%1.27%
NVO
Novo Nordisk A/S
4.87%3.31%1.68%1.00%1.20%1.35%1.87%2.14%1.45%1.52%2.87%0.92%
PFE
Pfizer Inc.
6.07%6.91%6.33%5.70%3.12%2.64%3.92%3.68%3.12%3.53%3.69%3.47%

Drawdowns

Drawdowns Chart

The Drawdowns chart displays portfolio losses from any high point along the way. Drawdowns are calculated considering price movements and all distributions paid, if any.


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Worst Drawdowns

The table below displays the maximum drawdowns of the DRUGS. A maximum drawdown is a measure of risk, indicating the largest reduction in portfolio value due to a series of losing trades.

The maximum drawdown for the DRUGS was 16.14%, occurring on Apr 10, 2025. Recovery took 70 trading sessions.

The current DRUGS drawdown is 7.39%.


Depth

Start

To Bottom

Bottom

To Recover

End

Total

-16.14%Mar 10, 202524Apr 10, 202570Jul 23, 202594
-12.26%Feb 19, 202622Mar 20, 2026
-7.94%Nov 15, 202430Dec 30, 202434Feb 20, 202564
-5.1%Jul 29, 20253Jul 31, 20259Aug 13, 202512
-4.78%Oct 6, 202518Oct 29, 202510Nov 12, 202528

Volatility

Volatility Chart

The chart below shows the rolling one-month volatility.


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Diversification

Diversification Metrics


Number of Effective Assets

The portfolio contains 20 assets, with an effective number of assets of 20.00, reflecting the diversification based on asset allocation. This number of effective assets suggests that the portfolio's investments are spread across a variety of assets, indicating a well-diversified allocation. However, true diversification also depends on the correlations between assets.

Asset Correlations Table

The table below displays the correlation coefficients between the individual components of the portfolio, the entire portfolio, and the chosen benchmark.

BenchmarkMDCXSCLXMIRAAMRNGRFSNVOOGNJNJLLYGILDSNYMRKBIIBAZNABBVBMYNVSPFEGSKAMGNPortfolio
Benchmark1.000.130.260.270.290.410.350.320.020.310.220.190.120.260.250.200.190.210.260.190.280.43
MDCX0.131.000.010.060.060.070.050.06-0.040.030.040.080.020.060.040.060.030.05-0.01-0.000.030.31
SCLX0.260.011.000.140.120.080.110.12-0.010.080.080.040.110.120.060.170.100.030.140.100.090.38
MIRA0.270.060.141.000.230.160.050.160.020.110.030.13-0.000.130.120.010.090.090.100.130.120.38
AMRN0.290.060.120.231.000.230.270.230.090.170.140.240.140.220.160.170.170.160.260.180.290.42
GRFS0.410.070.080.160.231.000.310.230.150.260.290.280.180.240.260.230.200.270.170.280.290.41
NVO0.350.050.110.050.270.311.000.240.170.380.270.300.270.280.360.360.350.350.360.340.360.48
OGN0.320.060.120.160.230.230.241.000.290.300.270.370.350.410.380.330.350.330.440.370.400.53
JNJ0.02-0.04-0.010.020.090.150.170.291.000.340.430.360.460.390.400.470.480.540.420.510.530.41
LLY0.310.030.080.110.170.260.380.300.341.000.270.290.380.430.440.410.410.410.370.330.410.47
GILD0.220.040.080.030.140.290.270.270.430.271.000.370.360.380.400.460.450.490.350.450.490.48
SNY0.190.080.040.130.240.280.300.370.360.290.371.000.450.410.540.410.440.490.470.560.380.55
MRK0.120.020.11-0.000.140.180.270.350.460.380.360.451.000.490.460.510.560.500.570.510.540.55
BIIB0.260.060.120.130.220.240.280.410.390.430.380.410.491.000.370.460.530.430.570.450.540.58
AZN0.250.040.060.120.160.260.360.380.400.440.400.540.460.371.000.480.470.620.490.650.450.56
ABBV0.200.060.170.010.170.230.360.330.470.410.460.410.510.460.481.000.580.550.520.510.590.57
BMY0.190.030.100.090.170.200.350.350.480.410.450.440.560.530.470.581.000.540.640.530.570.59
NVS0.210.050.030.090.160.270.350.330.540.410.490.490.500.430.620.550.541.000.540.630.580.58
PFE0.26-0.010.140.100.260.170.360.440.420.370.350.470.570.570.490.520.640.541.000.520.570.59
GSK0.19-0.000.100.130.180.280.340.370.510.330.450.560.510.450.650.510.530.630.521.000.570.58
AMGN0.280.030.090.120.290.290.360.400.530.410.490.380.540.540.450.590.570.580.570.571.000.60
Portfolio0.430.310.380.380.420.410.480.530.410.470.480.550.550.580.560.570.590.580.590.580.601.00
The correlation results are calculated based on daily price changes starting from Nov 15, 2024