VTGN vs. VT

Last updated Aug 1, 2026

VTGN (VistaGen Therapeutics, Inc.) is a stock, while VT (Vanguard Total World Stock ETF) is Global Equities fund tracking the FTSE Global All Cap Index. Over the past 10 years, VTGN returned -44.44%/yr vs 12.39%/yr for VT. Their 0.24 correlation means their historical movements had little consistent relationship.

Performance

VTGN vs. VT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in VistaGen Therapeutics, Inc. (VTGN) and Vanguard Total World Stock ETF (VT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, VTGN achieves a -63.59% return, which is significantly lower than VT's 11.15% return. Over the past 10 years, VTGN has underperformed VT with an annualized return of -44.44%, while VT has yielded a comparatively higher 12.39% annualized return.

VTGN

• 1D: 0.00%
• 1M: -3.17%
• 6M: -56.83%
• YTD: -63.59%
• 1Y: -91.75%
• 3Y*: -48.84%
• 5Y*: -68.67%
• 10Y*: -44.44%
• ALL TIME*: -48.39%

VT

• 1D: 0.26%
• 1M: -0.20%
• 6M: 7.80%
• YTD: 11.15%
• 1Y: 23.51%
• 3Y*: 18.19%
• 5Y*: 10.58%
• 10Y*: 12.39%
• ALL TIME*: 8.81%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
VT Vanguard Total World Stock ETF	$425.08M	$369.63M	$481.55M
VTGN VistaGen Therapeutics, Inc.	$201.44K	$332.74K	$731.92K

VTGN vs. VT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
VTGN VistaGen Therapeutics, Inc.	-63.59%	-77.56%	-42.61%	66.34%	-94.72%	0.52%	181.16%	-54.00%	35.14%	-70.24%
VT Vanguard Total World Stock ETF	11.15%	22.43%	16.49%	22.02%	-18.00%	18.27%	16.59%	26.81%	-9.76%	24.50%

Correlation

The correlation between VTGN and VT is 0.23, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.23
Correlation (3Y) Balances recent behavior with more history.	0.28
Correlation (5Y) Shows whether the relationship held over a longer period.	0.32
Correlation (10Y) Provides a long-term view across more market conditions.	0.24
Correlation (All Time) Calculated using the full available price history since May 6, 2016	0.24

Return for Risk

VTGN vs. VT — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

VTGN

VTGN Risk / Return Rank: 11
VTGN Sharpe Ratio Rank: 13
VTGN Sortino Ratio Rank: 17
VTGN Omega Ratio Rank: 10
VTGN Calmar Ratio Rank: 4
VTGN Martin Ratio Rank: 11

VT

VT Risk / Return Rank: 70
VT Sharpe Ratio Rank: 71
VT Sortino Ratio Rank: 69
VT Omega Ratio Rank: 69
VT Calmar Ratio Rank: 67
VT Martin Ratio Rank: 76

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

VTGN vs. VT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for VistaGen Therapeutics, Inc. (VTGN) and Vanguard Total World Stock ETF (VT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	VTGN	VT	Difference
Sharpe ratio: Return per unit of total volatility	-0.69	1.59	-2.28
Sortino ratio: Return per unit of downside risk	-0.72	2.23	-2.95
Omega ratio: Gain probability vs. loss probability	0.85	1.29	-0.44
Calmar ratio: Return relative to maximum drawdown	-0.96	2.29	-3.25
Martin ratio: Return relative to average drawdown	-1.31	9.54	-10.85

VTGN vs. VT - Sharpe Ratio Comparison

The current VTGN Sharpe Ratio is -0.69, which is lower than the VT Sharpe Ratio of 1.59. The chart below compares the historical Sharpe Ratios of VTGN and VT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

VTGN vs. VT - Drawdown Comparison

The maximum VTGN drawdown since its inception was -99.89%, which is greater than VT's maximum drawdown of -50.27%. Use the drawdown chart below to compare losses from any high point for VTGN and VT.

Drawdown Indicators

	VTGN	VT	Difference
Max Drawdown Largest peak-to-trough decline	-99.89%	-50.27%	-49.62%
Max Drawdown (1Y) Largest decline over 1 year	-95.39%	-9.67%	-85.72%
Max Drawdown (3Y) Largest decline over 3 years	-98.27%	-16.51%	-81.76%
Max Drawdown (5Y) Largest decline over 5 years	-99.76%	-26.38%	-73.38%
Max Drawdown (10Y) Largest decline over 10 years	-99.83%	-34.24%	-65.59%
Current Drawdown Current decline from peak	-99.89%	-1.84%	-98.05%
Average Drawdown Average peak-to-trough decline	-84.64%	-6.97%	-77.67%
Ulcer Index Depth and duration of drawdowns from previous peaks	69.71%	2.32%	+67.39%

Volatility

VTGN vs. VT - Volatility Comparison

VistaGen Therapeutics, Inc. (VTGN) has a higher volatility of 12.80% compared to Vanguard Total World Stock ETF (VT) at 3.99%. This indicates that VTGN's price experiences larger fluctuations and is considered to be riskier than VT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	VTGN	VT	Difference
Volatility (1M) Calculated over the trailing 1-month period	12.80%	3.99%	+8.81%
Volatility (6M) Calculated over the trailing 6-month period	131.72%	11.68%	+120.04%
Volatility (1Y) Calculated over the trailing 1-year period	132.16%	13.96%	+118.20%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	321.80%	16.22%	+305.58%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	241.03%	17.18%	+223.85%

Dividends

VTGN vs. VT - Dividend Comparison

VTGN has not paid dividends to shareholders, while VT's dividend yield for the trailing twelve months is around 1.59%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
VT Vanguard Total World Stock ETF	1.59%	1.82%	1.95%	2.08%	2.20%	1.82%	1.66%	2.32%	2.53%	2.11%	2.39%	2.45%
VTGN VistaGen Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both VTGN and VT in my portfolio?

VTGN and VT have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, VTGN or VT?

VTGN has higher volatility (12.80%) compared to VT (3.99%). In terms of maximum drawdown, VTGN dropped -99.89% vs VT's -50.27%.

Which has better risk-adjusted returns?

VT currently has the higher Sharpe Ratio (1.59 vs -0.69), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.