VTGN vs. VT

Last updated Jun 3, 2026

VTGN (VistaGen Therapeutics, Inc.) is a stock, while VT (Vanguard Total World Stock ETF) is Global Equities fund tracking the FTSE Global All Cap Index. Over the past 10 years, VTGN returned -41.10%/yr vs 12.74%/yr for VT. At a 0.24 correlation, their price movements are largely independent.

Performance

VTGN vs. VT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in VistaGen Therapeutics, Inc. (VTGN) and Vanguard Total World Stock ETF (VT). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, VTGN achieves a -12.37% return, which is significantly lower than VT's 12.24% return. Over the past 10 years, VTGN has underperformed VT with an annualized return of -41.10%, while VT has yielded a comparatively higher 12.74% annualized return.

VTGN

• 1D: -10.42%
• 1M: -7.32%
• YTD: -12.37%
• 6M: -83.89%
• 1Y: -76.08%
• 3Y*: -47.37%
• 5Y*: -61.81%
• 10Y*: -41.10%

VT

• 1D: -0.88%
• 1M: 4.91%
• YTD: 12.24%
• 6M: 13.14%
• 1Y: 29.24%
• 3Y*: 20.93%
• 5Y*: 10.99%
• 10Y*: 12.74%

*Multi-year figures are annualized to reflect compound growth (CAGR)

VTGN vs. VT - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
VTGN VistaGen Therapeutics, Inc.	-12.37%	-77.56%	-42.61%	66.34%	-94.72%	0.52%	181.16%	-54.00%	35.14%	-70.24%
VT Vanguard Total World Stock ETF	12.24%	22.43%	16.49%	22.02%	-18.00%	18.27%	16.59%	26.81%	-9.76%	24.50%

Correlation

The correlation between VTGN and VT is 0.26, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.26
Correlation (3Y) Calculated over the trailing 3-year period	0.28
Correlation (5Y) Calculated over the trailing 5-year period	0.32
Correlation (10Y) Calculated over the trailing 10-year period	0.25
Correlation (All Time) Calculated using the full available price history since May 9, 2016	0.24

Return for Risk

VTGN vs. VT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

VTGN

VTGN Risk / Return Rank: 14
VTGN Sharpe Ratio Rank: 12
VTGN Sortino Ratio Rank: 22
VTGN Omega Ratio Rank: 19
VTGN Calmar Ratio Rank: 7
VTGN Martin Ratio Rank: 10

VT

VT Risk / Return Rank: 67
VT Sharpe Ratio Rank: 68
VT Sortino Ratio Rank: 68
VT Omega Ratio Rank: 67
VT Calmar Ratio Rank: 60
VT Martin Ratio Rank: 71

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

VTGN vs. VT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for VistaGen Therapeutics, Inc. (VTGN) and Vanguard Total World Stock ETF (VT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	VTGN	VT	Difference
Sharpe ratio Return per unit of total volatility	-0.68	2.31	-3.00
Sortino ratio Return per unit of downside risk	-0.33	3.20	-3.53
Omega ratio Gain probability vs. loss probability	0.94	1.42	-0.48
Calmar ratio Return relative to maximum drawdown	-0.86	3.04	-3.90
Martin ratio Return relative to average drawdown	-1.31	13.53	-14.84
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

VTGN vs. VT - Sharpe Ratio Comparison

The current VTGN Sharpe Ratio is -0.68, which is lower than the VT Sharpe Ratio of 2.31. The chart below compares the historical Sharpe Ratios of VTGN and VT, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	VTGN	VT	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.68	2.31	-3.00
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.19	0.69	-0.88
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.17	0.74	-0.91
Sharpe Ratio (All Time) Calculated using the full available price history	-0.19	0.44	-0.62

Drawdowns

VTGN vs. VT - Drawdown Comparison

The maximum VTGN drawdown since its inception was -99.76%, which is greater than VT's maximum drawdown of -50.27%. Use the drawdown chart below to compare losses from any high point for VTGN and VT.

Drawdown Indicators

	VTGN	VT	Difference
Max Drawdown Largest peak-to-trough decline	-99.76%	-50.27%	-49.49%
Max Drawdown (1Y) Largest decline over 1 year	-89.69%	-9.67%	-80.02%
Max Drawdown (3Y) Largest decline over 3 years	-96.13%	-16.51%	-79.62%
Max Drawdown (5Y) Largest decline over 5 years	-99.51%	-26.38%	-73.13%
Max Drawdown (10Y) Largest decline over 10 years	-99.62%	-34.24%	-65.38%
Current Drawdown Current decline from peak	-99.72%	-0.88%	-98.84%
Average Drawdown Average peak-to-trough decline	-84.43%	-7.02%	-77.41%
Ulcer Index Depth and duration of drawdowns from previous peaks	59.20%	2.17%	+57.03%

Volatility

VTGN vs. VT - Volatility Comparison

VistaGen Therapeutics, Inc. (VTGN) has a higher volatility of 21.72% compared to Vanguard Total World Stock ETF (VT) at 3.83%. This indicates that VTGN's price experiences larger fluctuations and is considered to be riskier than VT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	VTGN	VT	Difference
Volatility (1M) Calculated over the trailing 1-month period	21.72%	3.83%	+17.89%
Volatility (6M) Calculated over the trailing 6-month period	171.65%	10.17%	+161.48%
Volatility (1Y) Calculated over the trailing 1-year period	111.75%	12.70%	+99.05%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	320.16%	16.05%	+304.11%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	240.05%	17.23%	+222.82%

Dividends

VTGN vs. VT - Dividend Comparison

VTGN has not paid dividends to shareholders, while VT's dividend yield for the trailing twelve months is around 1.59%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
VT Vanguard Total World Stock ETF	1.59%	1.82%	1.95%	2.08%	2.20%	1.82%	1.66%	2.32%	2.53%	2.11%	2.39%	2.45%
VTGN VistaGen Therapeutics, Inc.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both VTGN and VT in my portfolio?

VTGN and VT have a correlation of 0.26, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, VTGN or VT?

VTGN has higher volatility (21.72%) compared to VT (3.83%). In terms of maximum drawdown, VTGN dropped -99.76% vs VT's -50.27%.

Which has better risk-adjusted returns?

VT currently has the higher Sharpe Ratio (2.31 vs -0.68), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.