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VTGN vs. ACRV
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

VTGN vs. ACRV - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in VistaGen Therapeutics, Inc. (VTGN) and Acrivon Therapeutics Inc. Common Stock (ACRV). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, VTGN achieves a -63.59% return, which is significantly lower than ACRV's -37.76% return.


VTGN

1D
0.00%
1M
-3.17%
6M
-56.83%
YTD
-63.59%
1Y
-91.75%
3Y*
-48.84%
5Y*
-68.67%
10Y*
-44.44%
ALL TIME*
-48.39%

ACRV

1D
-1.32%
1M
-12.79%
6M
-16.20%
YTD
-37.76%
1Y
19.05%
3Y*
-50.62%
5Y*
10Y*
ALL TIME*
-44.55%
*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison


PositionAvg. Volume Value (2W)Avg. Volume Value (1M)Avg. Volume Value (3M)
$467.58K$869.81K$779.27K
$201.44K$332.74K$731.92K

VTGN vs. ACRV - Yearly Performance Comparison


2026 (YTD)2025202420232022
VTGN
VistaGen Therapeutics, Inc.
-63.59%-77.56%-42.61%66.34%-32.68%
ACRV
Acrivon Therapeutics Inc. Common Stock
-37.76%-59.97%22.36%-57.29%-13.71%

Correlation

The correlation between VTGN and ACRV is 0.23, which is low. Their historical price movements had little consistent relationship.


Correlation
Correlation (1Y)
Focuses on recent behavior, but can change the most.

0.23

Correlation (3Y)
Balances recent behavior with more history.

0.26

Correlation (All Time)
Calculated using the full available price history since Nov 15, 2022

0.24

Fundamentals

Market Cap

VTGN:

$9.89M

ACRV:

$64.20M

EPS

VTGN:

-$1.80

ACRV:

-$2.00

PB Ratio

VTGN:

0.26

ACRV:

0.61

Total Revenue (TTM)

VTGN:

$1.27M

ACRV:

$0.00

Gross Profit (TTM)

VTGN:

$522.00K

ACRV:

$311.00K

EBITDA (TTM)

VTGN:

-$68.97M

ACRV:

-$84.65M

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VistaGen Therapeutics, Inc.

Often compared with VTGN:
VTGN vs. VT
Often compared with ACRV:
ACRV vs. BVSACRV vs. HURAACRV vs. SSO

Return for Risk

VTGN vs. ACRV — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

VTGN
VTGN Risk / Return Rank: 1111
Overall Rank
VTGN Sharpe Ratio Rank: 1313
Sharpe Ratio Rank
VTGN Sortino Ratio Rank: 1717
Sortino Ratio Rank
VTGN Omega Ratio Rank: 1010
Omega Ratio Rank
VTGN Calmar Ratio Rank: 44
Calmar Ratio Rank
VTGN Martin Ratio Rank: 1111
Martin Ratio Rank

ACRV
ACRV Risk / Return Rank: 5454
Overall Rank
ACRV Sharpe Ratio Rank: 5151
Sharpe Ratio Rank
ACRV Sortino Ratio Rank: 5858
Sortino Ratio Rank
ACRV Omega Ratio Rank: 5858
Omega Ratio Rank
ACRV Calmar Ratio Rank: 5353
Calmar Ratio Rank
ACRV Martin Ratio Rank: 5151
Martin Ratio Rank
The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

VTGN vs. ACRV - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for VistaGen Therapeutics, Inc. (VTGN) and Acrivon Therapeutics Inc. Common Stock (ACRV). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


VTGNACRVDifference
Sharpe ratioReturn per unit of total volatility

-0.88

Sortino ratioReturn per unit of downside risk

-1.72

Omega ratioGain probability vs. loss probability

0.85

1.13

-0.28

Calmar ratioReturn relative to maximum drawdown

-0.96

0.30

-1.26

Martin ratioReturn relative to average drawdown

-1.31

0.52

-1.83

VTGN vs. ACRV - Sharpe Ratio Comparison

The current VTGN Sharpe Ratio is -0.69, which is lower than the ACRV Sharpe Ratio of 0.18. The chart below compares the historical Sharpe Ratios of VTGN and ACRV, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

VTGN vs. ACRV - Drawdown Comparison

The maximum VTGN drawdown since its inception was -99.89%, roughly equal to the maximum ACRV drawdown of -95.47%. Use the drawdown chart below to compare losses from any high point for VTGN and ACRV.


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Drawdown Indicators


VTGNACRVDifference

Max Drawdown

Largest peak-to-trough decline

-99.89%

-95.47%

-4.42%

Max Drawdown (1Y)

Largest decline over 1 year

-95.39%

-57.14%

-38.25%

Max Drawdown (3Y)

Largest decline over 3 years

-98.27%

-91.53%

-6.74%

Max Drawdown (5Y)

Largest decline over 5 years

-99.76%

Max Drawdown (10Y)

Largest decline over 10 years

-99.83%

Current Drawdown

Current decline from peak

-99.89%

-93.53%

-6.36%

Average Drawdown

Average peak-to-trough decline

-84.64%

-71.30%

-13.34%

Ulcer Index

Depth and duration of drawdowns from previous peaks

69.71%

33.25%

+36.46%

Volatility

VTGN vs. ACRV - Volatility Comparison

The current volatility for VistaGen Therapeutics, Inc. (VTGN) is 12.80%, while Acrivon Therapeutics Inc. Common Stock (ACRV) has a volatility of 23.22%. This indicates that VTGN experiences smaller price fluctuations and is considered to be less risky than ACRV based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


VTGNACRVDifference

Volatility (1M)

Calculated over the trailing 1-month period

12.80%

23.22%

-10.42%

Volatility (6M)

Calculated over the trailing 6-month period

131.72%

53.21%

+78.51%

Volatility (1Y)

Calculated over the trailing 1-year period

132.16%

93.40%

+38.76%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

321.80%

103.36%

+218.44%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

241.03%

103.36%

+137.67%

Dividends

VTGN vs. ACRV - Dividend Comparison

Neither VTGN nor ACRV has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

VTGN vs. ACRV - Financials Comparison

This section allows you to compare key financial metrics between VistaGen Therapeutics, Inc. and Acrivon Therapeutics Inc. Common Stock. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


Values in USD except per share items

Frequently Asked Questions


VTGN and ACRV have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

ACRV has higher volatility (23.22%) compared to VTGN (12.80%). In terms of maximum drawdown, VTGN dropped -99.89% vs ACRV's -95.47%.

ACRV currently has the higher Sharpe Ratio (0.18 vs -0.69), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

Find the right allocation for VTGN and ACRV

Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.

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