VERX vs. KRYS
VERX (Vertex, Inc.) and KRYS (Krystal Biotech, Inc.) are both stocks. VERX operates in Software - Application (Technology), while KRYS operates in Biotechnology (Healthcare). Over the past 5 years, VERX returned -6.32%/yr vs 37.68%/yr for KRYS. At a 0.24 correlation, their price movements are largely independent.
Performance
VERX vs. KRYS - Performance Comparison
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Returns By Period
In the year-to-date period, VERX achieves a -34.10% return, which is significantly lower than KRYS's 24.84% return.
VERX
- 1D
- 2.89%
- 1M
- -3.52%
- YTD
- -34.10%
- 6M
- -32.34%
- 1Y
- -68.23%
- 3Y*
- -15.07%
- 5Y*
- -6.32%
- 10Y*
- —
KRYS
- 1D
- 1.98%
- 1M
- 8.16%
- YTD
- 24.84%
- 6M
- 38.67%
- 1Y
- 133.12%
- 3Y*
- 36.21%
- 5Y*
- 37.68%
- 10Y*
- —
VERX vs. KRYS - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | |
|---|---|---|---|---|---|---|---|
VERX Vertex, Inc. | -34.10% | -62.57% | 98.03% | 85.67% | -8.57% | -54.46% | 45.63% |
KRYS Krystal Biotech, Inc. | 24.84% | 57.37% | 26.28% | 56.60% | 13.25% | 16.58% | 45.00% |
Correlation
The correlation between VERX and KRYS is 0.13, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.13 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.18 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.25 |
Correlation (All Time) Calculated using the full available price history since Jul 30, 2020 | 0.24 |
The correlation between VERX and KRYS shifts across timeframes, from 0.13 (1 year) to 0.25 (5 years), reflecting how their relationship changes across market environments.
Fundamentals
VERX:
-$0.05
KRYS:
$7.50
VERX:
2.13
KRYS:
22.13
VERX:
$768.03M
KRYS:
$417.30M
VERX:
$486.52M
KRYS:
$387.24M
VERX:
$51.70M
KRYS:
$185.45M
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Return for Risk
VERX vs. KRYS — Risk / Return Rank
VERX
KRYS
VERX vs. KRYS - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Vertex, Inc. (VERX) and Krystal Biotech, Inc. (KRYS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| VERX | KRYS | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | -4.61 | ||
| Sortino ratioReturn per unit of downside risk | -5.83 | ||
| Omega ratioGain probability vs. loss probability | 0.74 | 1.50 | -0.77 |
| Calmar ratioReturn relative to maximum drawdown | -0.92 | 8.40 | -9.32 |
| Martin ratioReturn relative to average drawdown | -1.31 | 21.78 | -23.09 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| VERX | KRYS | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | -1.17 | 3.45 | -4.61 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.12 | 0.50 | -0.61 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.18 | 0.64 | -0.81 |
Drawdowns
VERX vs. KRYS - Drawdown Comparison
The maximum VERX drawdown since its inception was -81.68%, which is greater than KRYS's maximum drawdown of -53.42%. Use the drawdown chart below to compare losses from any high point for VERX and KRYS.
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Drawdown Indicators
| VERX | KRYS | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -81.68% | -53.42% | -28.26% |
Max Drawdown (1Y)Largest decline over 1 year | -74.21% | -15.94% | -58.27% |
Max Drawdown (3Y)Largest decline over 3 years | -81.68% | -42.26% | -39.42% |
Max Drawdown (5Y)Largest decline over 5 years | -81.68% | -44.55% | -37.13% |
Current DrawdownCurrent decline from peak | -77.68% | -2.69% | -74.99% |
Average DrawdownAverage peak-to-trough decline | -42.26% | -16.21% | -26.05% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 52.15% | 6.14% | +46.01% |
Volatility
VERX vs. KRYS - Volatility Comparison
Vertex, Inc. (VERX) has a higher volatility of 27.77% compared to Krystal Biotech, Inc. (KRYS) at 10.33%. This indicates that VERX's price experiences larger fluctuations and is considered to be riskier than KRYS based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| VERX | KRYS | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 27.77% | 10.33% | +17.44% |
Volatility (6M)Calculated over the trailing 6-month period | 47.63% | 27.25% | +20.38% |
Volatility (1Y)Calculated over the trailing 1-year period | 58.63% | 38.86% | +19.77% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 54.50% | 76.43% | -21.93% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 55.71% | 74.22% | -18.51% |
Dividends
VERX vs. KRYS - Dividend Comparison
Neither VERX nor KRYS has paid dividends to shareholders.
Financials
VERX vs. KRYS - Financials Comparison
This section allows you to compare key financial metrics between Vertex, Inc. and Krystal Biotech, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
VERX vs. KRYS - Profitability Comparison
VERX - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Vertex, Inc. reported a gross profit of 124.87M and revenue of 196.65M. Therefore, the gross margin over that period was 63.5%.
KRYS - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Jun 2026, Krystal Biotech, Inc. reported a gross profit of 110.03M and revenue of 116.36M. Therefore, the gross margin over that period was 94.6%.
VERX - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Vertex, Inc. reported an operating income of -10.61M and revenue of 196.65M, resulting in an operating margin of -5.4%.
KRYS - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Jun 2026, Krystal Biotech, Inc. reported an operating income of 53.69M and revenue of 116.36M, resulting in an operating margin of 46.1%.
VERX - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Vertex, Inc. reported a net income of -2.51M and revenue of 196.65M, resulting in a net margin of -1.3%.
KRYS - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Jun 2026, Krystal Biotech, Inc. reported a net income of 55.93M and revenue of 116.36M, resulting in a net margin of 48.1%.
Frequently Asked Questions
VERX and KRYS have a correlation of 0.13, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
VERX has higher volatility (27.77%) compared to KRYS (10.33%). In terms of maximum drawdown, VERX dropped -81.68% vs KRYS's -53.42%.
KRYS currently has the higher Sharpe Ratio (3.45 vs -1.17), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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