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UTHR vs. SRPT
Performance
Return for Risk
Dividends
Drawdowns
Volatility
Financials

Performance

UTHR vs. SRPT - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in United Therapeutics Corporation (UTHR) and Sarepta Therapeutics, Inc. (SRPT). The values are adjusted to include any dividend payments, if applicable.

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UTHR vs. SRPT - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
UTHR
United Therapeutics Corporation
21.70%38.09%60.46%-20.93%28.70%42.35%72.33%-19.12%-26.39%3.15%
SRPT
Sarepta Therapeutics, Inc.
1.12%-82.30%26.09%-25.58%43.90%-47.18%32.12%18.24%96.14%102.84%

Fundamentals

Market Cap

UTHR:

$28.40B

SRPT:

$2.28B

EPS

UTHR:

$27.90

SRPT:

-$8.11

PS Ratio

UTHR:

8.91

SRPT:

1.03

PB Ratio

UTHR:

4.00

SRPT:

2.00

Total Revenue (TTM)

UTHR:

$3.18B

SRPT:

$2.20B

Gross Profit (TTM)

UTHR:

$2.80B

SRPT:

-$1.05B

EBITDA (TTM)

UTHR:

$1.82B

SRPT:

-$778.95M

Returns By Period

In the year-to-date period, UTHR achieves a 21.70% return, which is significantly higher than SRPT's 1.12% return. Over the past 10 years, UTHR has outperformed SRPT with an annualized return of 18.04%, while SRPT has yielded a comparatively lower 0.86% annualized return.


UTHR

1D
0.79%
1M
17.68%
YTD
21.70%
6M
41.45%
1Y
92.36%
3Y*
38.34%
5Y*
25.25%
10Y*
18.04%

SRPT

1D
6.25%
1M
29.83%
YTD
1.12%
6M
12.92%
1Y
-65.90%
3Y*
-45.95%
5Y*
-22.17%
10Y*
0.86%
*Multi-year figures are annualized to reflect compound growth (CAGR)

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Return for Risk

UTHR vs. SRPT — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

UTHR
UTHR Risk / Return Rank: 9393
Overall Rank
UTHR Sharpe Ratio Rank: 8989
Sharpe Ratio Rank
UTHR Sortino Ratio Rank: 9494
Sortino Ratio Rank
UTHR Omega Ratio Rank: 9494
Omega Ratio Rank
UTHR Calmar Ratio Rank: 9595
Calmar Ratio Rank
UTHR Martin Ratio Rank: 9494
Martin Ratio Rank

SRPT
SRPT Risk / Return Rank: 1717
Overall Rank
SRPT Sharpe Ratio Rank: 1616
Sharpe Ratio Rank
SRPT Sortino Ratio Rank: 2020
Sortino Ratio Rank
SRPT Omega Ratio Rank: 1818
Omega Ratio Rank
SRPT Calmar Ratio Rank: 1111
Calmar Ratio Rank
SRPT Martin Ratio Rank: 2222
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

UTHR vs. SRPT - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for United Therapeutics Corporation (UTHR) and Sarepta Therapeutics, Inc. (SRPT). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


UTHRSRPTDifference

Sharpe ratio

Return per unit of total volatility

1.84

-0.60

+2.44

Sortino ratio

Return per unit of downside risk

3.30

-0.47

+3.77

Omega ratio

Gain probability vs. loss probability

1.46

0.93

+0.53

Calmar ratio

Return relative to maximum drawdown

5.70

-0.85

+6.55

Martin ratio

Return relative to average drawdown

14.49

-1.09

+15.58

UTHR vs. SRPT - Sharpe Ratio Comparison

The current UTHR Sharpe Ratio is 1.84, which is higher than the SRPT Sharpe Ratio of -0.60. The chart below compares the historical Sharpe Ratios of UTHR and SRPT, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


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Sharpe Ratios by Period


UTHRSRPTDifference

Sharpe Ratio (1Y)

Calculated over the trailing 1-year period

1.84

-0.60

+2.44

Sharpe Ratio (5Y)

Calculated over the trailing 5-year period

0.72

-0.32

+1.04

Sharpe Ratio (10Y)

Calculated over the trailing 10-year period

0.51

0.01

+0.50

Sharpe Ratio (All Time)

Calculated using the full available price history

0.39

-0.02

+0.41

Correlation

The correlation between UTHR and SRPT is 0.24, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


Dividends

UTHR vs. SRPT - Dividend Comparison

Neither UTHR nor SRPT has paid dividends to shareholders.


Tickers have no history of dividend payments

Drawdowns

UTHR vs. SRPT - Drawdown Comparison

The maximum UTHR drawdown since its inception was -93.18%, smaller than the maximum SRPT drawdown of -98.17%. Use the drawdown chart below to compare losses from any high point for UTHR and SRPT.


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Drawdown Indicators


UTHRSRPTDifference

Max Drawdown

Largest peak-to-trough decline

-93.18%

-98.17%

+4.99%

Max Drawdown (1Y)

Largest decline over 1 year

-16.35%

-81.26%

+64.91%

Max Drawdown (5Y)

Largest decline over 5 years

-33.00%

-92.72%

+59.72%

Max Drawdown (10Y)

Largest decline over 10 years

-55.56%

-93.33%

+37.77%

Current Drawdown

Current decline from peak

0.00%

-87.83%

+87.83%

Average Drawdown

Average peak-to-trough decline

-35.53%

-68.01%

+32.48%

Ulcer Index

Depth and duration of drawdowns from previous peaks

6.43%

63.49%

-57.06%

Volatility

UTHR vs. SRPT - Volatility Comparison

The current volatility for United Therapeutics Corporation (UTHR) is 17.05%, while Sarepta Therapeutics, Inc. (SRPT) has a volatility of 35.20%. This indicates that UTHR experiences smaller price fluctuations and is considered to be less risky than SRPT based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


UTHRSRPTDifference

Volatility (1M)

Calculated over the trailing 1-month period

17.05%

35.20%

-18.15%

Volatility (6M)

Calculated over the trailing 6-month period

26.84%

70.73%

-43.89%

Volatility (1Y)

Calculated over the trailing 1-year period

50.41%

110.30%

-59.89%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

35.89%

69.77%

-33.88%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

35.32%

75.48%

-40.16%

Financials

UTHR vs. SRPT - Financials Comparison

This section allows you to compare key financial metrics between United Therapeutics Corporation and Sarepta Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


100.00M200.00M300.00M400.00M500.00M600.00M700.00M800.00MAprilJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober
790.20M
442.93M
(UTHR) Total Revenue
(SRPT) Total Revenue
Values in USD except per share items