TENX vs. TPST

Last updated Apr 1, 2026

Compare and contrast key facts about Tenax Therapeutics, Inc. (TENX) and Tempest Therapeutics, Inc. (TPST).

Performance

TENX vs. TPST - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Tenax Therapeutics, Inc. (TENX) and Tempest Therapeutics, Inc. (TPST). The values are adjusted to include any dividend payments, if applicable.

TENX vs. TPST - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
TENX Tenax Therapeutics, Inc.	31.17%	96.93%	-71.82%	-87.67%	-89.29%	-44.09%	31.91%	16.53%	-87.65%	-74.87%
TPST Tempest Therapeutics, Inc.	-42.86%	-73.54%	-81.03%	282.61%	-78.22%	-83.55%	-68.25%	-15.22%	-62.14%	-8.50%

Fundamentals

Market Cap TENX : $627.08M TPST : $6.81M
EPS TENX : -$1.33 TPST : -$6.36
PB Ratio TENX : 6.46 TPST : 1.02
Total Revenue (TTM) TENX : $0.00 TPST : $0.00
Gross Profit (TTM) TENX : $0.00 TPST : -$133.00K
EBITDA (TTM) TENX : $0.00 TPST : -$10.27M

Returns By Period

In the year-to-date period, TENX achieves a 31.17% return, which is significantly higher than TPST's -42.86% return. Over the past 10 years, TENX has outperformed TPST with an annualized return of -56.42%, while TPST has yielded a comparatively lower -62.01% annualized return.

TENX

• 1D: 14.13%
• 1M: 33.25%
• YTD: 31.17%
• 6M: 110.12%
• 1Y: 144.12%
• 3Y*: -24.53%
• 5Y*: -65.06%
• 10Y*: -56.42%

TPST

• 1D: 7.89%
• 1M: -28.07%
• YTD: -42.86%
• 6M: -84.05%
• 1Y: -82.91%
• 3Y*: -62.11%
• 5Y*: -63.34%
• 10Y*: -62.01%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

TENX vs. TPST — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

TENX

TENX Risk / Return Rank: 90
TENX Sharpe Ratio Rank: 92
TENX Sortino Ratio Rank: 92
TENX Omega Ratio Rank: 90
TENX Calmar Ratio Rank: 89
TENX Martin Ratio Rank: 89

TPST

TPST Risk / Return Rank: 6
TPST Sharpe Ratio Rank: 9
TPST Sortino Ratio Rank: 7
TPST Omega Ratio Rank: 6
TPST Calmar Ratio Rank: 5
TPST Martin Ratio Rank: 5

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

TENX vs. TPST - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Tenax Therapeutics, Inc. (TENX) and Tempest Therapeutics, Inc. (TPST). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	TENX	TPST	Difference
Sharpe ratio Return per unit of total volatility	2.15	-0.80	+2.95
Sortino ratio Return per unit of downside risk	3.10	-1.39	+4.49
Omega ratio Gain probability vs. loss probability	1.39	0.80	+0.59
Calmar ratio Return relative to maximum drawdown	3.53	-0.96	+4.49
Martin ratio Return relative to average drawdown	9.85	-1.68	+11.53
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

TENX vs. TPST - Sharpe Ratio Comparison

The current TENX Sharpe Ratio is 2.15, which is higher than the TPST Sharpe Ratio of -0.80. The chart below compares the historical Sharpe Ratios of TENX and TPST, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	TENX	TPST	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	2.15	-0.80	+2.95
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.39	-0.04	-0.36
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.39	-0.05	-0.34
Sharpe Ratio (All Time) Calculated using the full available price history	-0.25	-0.05	-0.21

Correlation

The correlation between TENX and TPST is 0.10, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

TENX vs. TPST - Dividend Comparison

Neither TENX nor TPST has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

TENX vs. TPST - Drawdown Comparison

The maximum TENX drawdown since its inception was -100.00%, roughly equal to the maximum TPST drawdown of -100.00%. Use the drawdown chart below to compare losses from any high point for TENX and TPST.

Drawdown Indicators

	TENX	TPST	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-100.00%	0.00%
Max Drawdown (1Y) Largest decline over 1 year	-41.49%	-87.15%	+45.66%
Max Drawdown (5Y) Largest decline over 5 years	-99.92%	-99.52%	-0.40%
Max Drawdown (10Y) Largest decline over 10 years	-100.00%	-100.00%	0.00%
Current Drawdown Current decline from peak	-100.00%	-100.00%	0.00%
Average Drawdown Average peak-to-trough decline	-87.49%	-82.65%	-4.84%
Ulcer Index Depth and duration of drawdowns from previous peaks	14.85%	49.91%	-35.06%

Volatility

TENX vs. TPST - Volatility Comparison

Tenax Therapeutics, Inc. (TENX) has a higher volatility of 37.22% compared to Tempest Therapeutics, Inc. (TPST) at 29.88%. This indicates that TENX's price experiences larger fluctuations and is considered to be riskier than TPST based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	TENX	TPST	Difference
Volatility (1M) Calculated over the trailing 1-month period	37.22%	29.88%	+7.34%
Volatility (6M) Calculated over the trailing 6-month period	59.47%	92.95%	-33.48%
Volatility (1Y) Calculated over the trailing 1-year period	67.52%	103.55%	-36.03%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	165.40%	1,784.28%	-1,618.88%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	143.86%	1,262.43%	-1,118.57%

Financials