SMLR vs. MSTR

Last updated Aug 1, 2026

SMLR (Semler Scientific, Inc.) and MSTR (Strategy Inc) are both stocks. SMLR operates in Medical Devices (Healthcare), while MSTR operates in Software - Application (Technology). Their 0.23 correlation means their historical movements had little consistent relationship.

Performance

SMLR vs. MSTR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Semler Scientific, Inc. (SMLR) and Strategy Inc (MSTR). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

SMLR

• 1D: —
• 1M: —
• 6M: —
• YTD: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —
• ALL TIME*: —

MSTR

• 1D: -4.56%
• 1M: -7.43%
• 6M: -37.69%
• YTD: -38.61%
• 1Y: -74.56%
• 3Y*: 28.96%
• 5Y*: 8.30%
• 10Y*: 18.75%
• ALL TIME*: 9.12%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
MSTR Strategy Inc	$1.53B	$1.65B	$2.43B

SMLR vs. MSTR - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
SMLR Semler Scientific, Inc.	32.96%	-71.69%	21.92%	34.21%	-63.99%	-2.50%	95.83%	39.53%	330.00%	451.72%
MSTR Strategy Inc	-38.61%	-47.53%	358.54%	346.15%	-74.00%	40.13%	172.42%	11.65%	-2.70%	-33.49%

Correlation

The correlation between SMLR and MSTR is 0.40, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.40
Correlation (3Y) Balances recent behavior with more history.	0.40
Correlation (5Y) Shows whether the relationship held over a longer period.	0.36
Correlation (10Y) Provides a long-term view across more market conditions.	0.27
Correlation (All Time) Calculated using the full available price history since Feb 21, 2014	0.23

The correlation between SMLR and MSTR shifts across timeframes, from 0.23 (all time) to 0.40 (3 years), reflecting how their relationship changes across market environments.

Fundamentals

Market Cap SMLR : $336.36M MSTR : $30.86B
EPS SMLR : $3.22 MSTR : -$97.96
PS Ratio SMLR : 8.26 MSTR : 59.67
PB Ratio SMLR : 0.73 MSTR : 1.95
Total Revenue (TTM) SMLR : $36.96M MSTR : $498.35M
Gross Profit (TTM) SMLR : $33.54M MSTR : $336.89M
EBITDA (TTM) SMLR : -$46.64M MSTR : -$36.86B

Return for Risk

SMLR vs. MSTR — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

SMLR

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

MSTR

MSTR Risk / Return Rank: 5
MSTR Sharpe Ratio Rank: 4
MSTR Sortino Ratio Rank: 2
MSTR Omega Ratio Rank: 5
MSTR Calmar Ratio Rank: 4
MSTR Martin Ratio Rank: 9

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

SMLR vs. MSTR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Semler Scientific, Inc. (SMLR) and Strategy Inc (MSTR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	SMLR	MSTR	Difference
Sharpe ratio: Return per unit of total volatility	—	-1.02	—
Sortino ratio: Return per unit of downside risk	—	-2.18	—
Omega ratio: Gain probability vs. loss probability	—	0.78	—
Calmar ratio: Return relative to maximum drawdown	—	-0.97	—
Martin ratio: Return relative to average drawdown	—	-1.38	—

Drawdowns

Drawdown Indicators

	SMLR	MSTR	Difference
Max Drawdown Largest peak-to-trough decline	—	-99.86%	—
Max Drawdown (1Y) Largest decline over 1 year	—	-79.53%	—
Max Drawdown (3Y) Largest decline over 3 years	—	-82.63%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-84.11%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-89.27%	—
Current Drawdown Current decline from peak	—	-80.31%	—
Average Drawdown Average peak-to-trough decline	—	-86.42%	—
Ulcer Index Depth and duration of drawdowns from previous peaks	—	55.64%	—

Volatility

Volatility by Period

	SMLR	MSTR	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	18.58%	—
Volatility (6M) Calculated over the trailing 6-month period	—	60.57%	—
Volatility (1Y) Calculated over the trailing 1-year period	—	75.24%	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	—	89.94%	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	—	74.33%	—

Dividends

SMLR vs. MSTR - Dividend Comparison

Neither SMLR nor MSTR has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both SMLR and MSTR in my portfolio?

SMLR and MSTR have a correlation of 0.40, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.