SGMO vs. MRSN

Last updated Apr 2, 2026

Compare and contrast key facts about Sangamo Therapeutics, Inc. (SGMO) and Mersana Therapeutics, Inc. (MRSN).

Performance

SGMO vs. MRSN - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Sangamo Therapeutics, Inc. (SGMO) and Mersana Therapeutics, Inc. (MRSN). The values are adjusted to include any dividend payments, if applicable.

SGMO vs. MRSN - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
SGMO Sangamo Therapeutics, Inc.	-38.07%	-58.82%	87.74%	-82.70%	-58.13%	-51.94%	86.44%	-27.09%	-30.00%	81.22%
MRSN Mersana Therapeutics, Inc.	0.52%	-19.08%	-38.36%	-60.41%	-5.79%	-76.63%	364.40%	40.44%	-75.17%	17.36%

Fundamentals

Market Cap SGMO : $87.84M MRSN : $145.02M
EPS SGMO : -$0.41 MRSN : -$14.05
PS Ratio SGMO : 1.97 MRSN : 4.37
Total Revenue (TTM) SGMO : $39.55M MRSN : $33.18M
Gross Profit (TTM) SGMO : $25.32M MRSN : $32.89M
EBITDA (TTM) SGMO : -$117.16M MRSN : -$66.25M

Returns By Period

SGMO

• 1D: 5.35%
• 1M: -39.50%
• YTD: -38.07%
• 6M: -61.44%
• 1Y: -54.38%
• 3Y*: -47.13%
• 5Y*: -53.74%
• 10Y*: -27.19%

MRSN

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

SGMO vs. MRSN — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SGMO

SGMO Risk / Return Rank: 16
SGMO Sharpe Ratio Rank: 18
SGMO Sortino Ratio Rank: 23
SGMO Omega Ratio Rank: 23
SGMO Calmar Ratio Rank: 9
SGMO Martin Ratio Rank: 8

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

SGMO vs. MRSN - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Sangamo Therapeutics, Inc. (SGMO) and Mersana Therapeutics, Inc. (MRSN). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	SGMO	MRSN	Difference
Sharpe ratio Return per unit of total volatility	-0.51	—	—
Sortino ratio Return per unit of downside risk	-0.26	—	—
Omega ratio Gain probability vs. loss probability	0.97	—	—
Calmar ratio Return relative to maximum drawdown	-0.87	—	—
Martin ratio Return relative to average drawdown	-1.54	—	—
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

Sharpe Ratios by Period

	SGMO	MRSN	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.51	—	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.51	—	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	-0.29	—	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.16	—	—

Correlation

The correlation between SGMO and MRSN is 0.36, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

SGMO vs. MRSN - Dividend Comparison

Neither SGMO nor MRSN has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

Drawdown Indicators

	SGMO	MRSN	Difference
Max Drawdown Largest peak-to-trough decline	-99.50%	—	—
Max Drawdown (1Y) Largest decline over 1 year	-69.70%	—	—
Max Drawdown (5Y) Largest decline over 5 years	-98.05%	—	—
Max Drawdown (10Y) Largest decline over 10 years	-99.06%	—	—
Current Drawdown Current decline from peak	-99.48%	—	—
Average Drawdown Average peak-to-trough decline	-83.93%	—	—
Ulcer Index Depth and duration of drawdowns from previous peaks	39.13%	—	—

Volatility

Volatility by Period

	SGMO	MRSN	Difference
Volatility (1M) Calculated over the trailing 1-month period	28.34%	—	—
Volatility (6M) Calculated over the trailing 6-month period	78.81%	—	—
Volatility (1Y) Calculated over the trailing 1-year period	108.44%	—	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	106.51%	—	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	95.01%	—	—

Financials