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SAVA vs. VOO
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between SAVA and VOO is 0.27, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


-0.50.00.51.0
Correlation: 0.3

Performance

SAVA vs. VOO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Cassava Sciences, Inc. (SAVA) and Vanguard S&P 500 ETF (VOO). The values are adjusted to include any dividend payments, if applicable.

0.00%200.00%400.00%600.00%NovemberDecember2025FebruaryMarchApril
-93.39%
557.08%
SAVA
VOO

Key characteristics

Sharpe Ratio

SAVA:

-0.64

VOO:

0.54

Sortino Ratio

SAVA:

-0.77

VOO:

0.88

Omega Ratio

SAVA:

0.87

VOO:

1.13

Calmar Ratio

SAVA:

-0.93

VOO:

0.55

Martin Ratio

SAVA:

-1.48

VOO:

2.27

Ulcer Index

SAVA:

62.61%

VOO:

4.55%

Daily Std Dev

SAVA:

143.91%

VOO:

19.19%

Max Drawdown

SAVA:

-99.18%

VOO:

-33.99%

Current Drawdown

SAVA:

-98.84%

VOO:

-9.90%

Returns By Period

In the year-to-date period, SAVA achieves a -33.47% return, which is significantly lower than VOO's -5.74% return. Over the past 10 years, SAVA has underperformed VOO with an annualized return of -19.87%, while VOO has yielded a comparatively higher 12.24% annualized return.


SAVA

YTD

-33.47%

1M

-4.85%

6M

-94.09%

1Y

-92.97%

5Y*

-26.77%

10Y*

-19.87%

VOO

YTD

-5.74%

1M

-0.92%

6M

-4.28%

1Y

9.78%

5Y*

15.84%

10Y*

12.24%

*Annualized

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Risk-Adjusted Performance

SAVA vs. VOO — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SAVA
The Risk-Adjusted Performance Rank of SAVA is 1212
Overall Rank
The Sharpe Ratio Rank of SAVA is 1717
Sharpe Ratio Rank
The Sortino Ratio Rank of SAVA is 1818
Sortino Ratio Rank
The Omega Ratio Rank of SAVA is 1313
Omega Ratio Rank
The Calmar Ratio Rank of SAVA is 22
Calmar Ratio Rank
The Martin Ratio Rank of SAVA is 99
Martin Ratio Rank

VOO
The Risk-Adjusted Performance Rank of VOO is 6464
Overall Rank
The Sharpe Ratio Rank of VOO is 6161
Sharpe Ratio Rank
The Sortino Ratio Rank of VOO is 6262
Sortino Ratio Rank
The Omega Ratio Rank of VOO is 6464
Omega Ratio Rank
The Calmar Ratio Rank of VOO is 6767
Calmar Ratio Rank
The Martin Ratio Rank of VOO is 6565
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

SAVA vs. VOO - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Cassava Sciences, Inc. (SAVA) and Vanguard S&P 500 ETF (VOO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


The chart of Sharpe ratio for SAVA, currently valued at -0.64, compared to the broader market-2.00-1.000.001.002.003.00
SAVA: -0.64
VOO: 0.54
The chart of Sortino ratio for SAVA, currently valued at -0.77, compared to the broader market-6.00-4.00-2.000.002.004.00
SAVA: -0.77
VOO: 0.88
The chart of Omega ratio for SAVA, currently valued at 0.87, compared to the broader market0.501.001.502.00
SAVA: 0.87
VOO: 1.13
The chart of Calmar ratio for SAVA, currently valued at -0.93, compared to the broader market0.001.002.003.004.005.00
SAVA: -0.93
VOO: 0.55
The chart of Martin ratio for SAVA, currently valued at -1.48, compared to the broader market-5.000.005.0010.0015.0020.00
SAVA: -1.48
VOO: 2.27

The current SAVA Sharpe Ratio is -0.64, which is lower than the VOO Sharpe Ratio of 0.54. The chart below compares the historical Sharpe Ratios of SAVA and VOO, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.004.00NovemberDecember2025FebruaryMarchApril
-0.64
0.54
SAVA
VOO

Dividends

SAVA vs. VOO - Dividend Comparison

SAVA has not paid dividends to shareholders, while VOO's dividend yield for the trailing twelve months is around 1.38%.


TTM20242023202220212020201920182017201620152014
SAVA
Cassava Sciences, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
VOO
Vanguard S&P 500 ETF
1.38%1.24%1.46%1.69%1.25%1.54%1.88%2.06%1.78%2.02%2.10%1.85%

Drawdowns

SAVA vs. VOO - Drawdown Comparison

The maximum SAVA drawdown since its inception was -99.18%, which is greater than VOO's maximum drawdown of -33.99%. Use the drawdown chart below to compare losses from any high point for SAVA and VOO. For additional features, visit the drawdowns tool.


-100.00%-80.00%-60.00%-40.00%-20.00%0.00%NovemberDecember2025FebruaryMarchApril
-98.84%
-9.90%
SAVA
VOO

Volatility

SAVA vs. VOO - Volatility Comparison

Cassava Sciences, Inc. (SAVA) has a higher volatility of 25.61% compared to Vanguard S&P 500 ETF (VOO) at 13.96%. This indicates that SAVA's price experiences larger fluctuations and is considered to be riskier than VOO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


0.00%50.00%100.00%150.00%200.00%NovemberDecember2025FebruaryMarchApril
25.61%
13.96%
SAVA
VOO