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SANA vs. SMH
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between SANA and SMH is 0.33, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


-0.50.00.51.00.3

Performance

SANA vs. SMH - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Sana Biotechnology, Inc. (SANA) and VanEck Vectors Semiconductor ETF (SMH). The values are adjusted to include any dividend payments, if applicable.

-80.00%-60.00%-40.00%-20.00%0.00%SeptemberOctoberNovemberDecember2025February
-47.60%
4.25%
SANA
SMH

Key characteristics

Sharpe Ratio

SANA:

-0.35

SMH:

0.78

Sortino Ratio

SANA:

0.02

SMH:

1.22

Omega Ratio

SANA:

1.00

SMH:

1.16

Calmar Ratio

SANA:

-0.67

SMH:

1.14

Martin Ratio

SANA:

-1.16

SMH:

2.62

Ulcer Index

SANA:

55.60%

SMH:

10.81%

Daily Std Dev

SANA:

184.47%

SMH:

36.15%

Max Drawdown

SANA:

-96.32%

SMH:

-83.29%

Current Drawdown

SANA:

-92.97%

SMH:

-7.94%

Returns By Period

In the year-to-date period, SANA achieves a 87.73% return, which is significantly higher than SMH's 6.45% return.


SANA

YTD

87.73%

1M

4.79%

6M

-46.41%

1Y

-61.70%

5Y*

N/A

10Y*

N/A

SMH

YTD

6.45%

1M

-1.75%

6M

6.82%

1Y

31.77%

5Y*

29.79%

10Y*

26.26%

*Annualized

Compare stocks, funds, or ETFs

Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.


Risk-Adjusted Performance

SANA vs. SMH — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SANA
The Risk-Adjusted Performance Rank of SANA is 2424
Overall Rank
The Sharpe Ratio Rank of SANA is 2828
Sharpe Ratio Rank
The Sortino Ratio Rank of SANA is 3333
Sortino Ratio Rank
The Omega Ratio Rank of SANA is 3232
Omega Ratio Rank
The Calmar Ratio Rank of SANA is 99
Calmar Ratio Rank
The Martin Ratio Rank of SANA is 1717
Martin Ratio Rank

SMH
The Risk-Adjusted Performance Rank of SMH is 3333
Overall Rank
The Sharpe Ratio Rank of SMH is 2929
Sharpe Ratio Rank
The Sortino Ratio Rank of SMH is 3030
Sortino Ratio Rank
The Omega Ratio Rank of SMH is 3232
Omega Ratio Rank
The Calmar Ratio Rank of SMH is 4646
Calmar Ratio Rank
The Martin Ratio Rank of SMH is 2929
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

SANA vs. SMH - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Sana Biotechnology, Inc. (SANA) and VanEck Vectors Semiconductor ETF (SMH). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


Sharpe ratio
The chart of Sharpe ratio for SANA, currently valued at -0.35, compared to the broader market-2.000.002.00-0.350.78
The chart of Sortino ratio for SANA, currently valued at 0.02, compared to the broader market-4.00-2.000.002.004.006.000.021.22
The chart of Omega ratio for SANA, currently valued at 1.00, compared to the broader market0.501.001.502.001.001.16
The chart of Calmar ratio for SANA, currently valued at -0.67, compared to the broader market0.002.004.006.00-0.671.14
The chart of Martin ratio for SANA, currently valued at -1.16, compared to the broader market-10.000.0010.0020.0030.00-1.162.62
SANA
SMH

The current SANA Sharpe Ratio is -0.35, which is lower than the SMH Sharpe Ratio of 0.78. The chart below compares the historical Sharpe Ratios of SANA and SMH, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.00SeptemberOctoberNovemberDecember2025February
-0.35
0.78
SANA
SMH

Dividends

SANA vs. SMH - Dividend Comparison

SANA has not paid dividends to shareholders, while SMH's dividend yield for the trailing twelve months is around 0.42%.


TTM20242023202220212020201920182017201620152014
SANA
Sana Biotechnology, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
SMH
VanEck Vectors Semiconductor ETF
0.42%0.44%0.60%1.18%0.51%0.69%1.50%1.88%1.43%0.80%2.14%1.16%

Drawdowns

SANA vs. SMH - Drawdown Comparison

The maximum SANA drawdown since its inception was -96.32%, which is greater than SMH's maximum drawdown of -83.29%. Use the drawdown chart below to compare losses from any high point for SANA and SMH. For additional features, visit the drawdowns tool.


-100.00%-80.00%-60.00%-40.00%-20.00%0.00%SeptemberOctoberNovemberDecember2025February
-92.97%
-7.94%
SANA
SMH

Volatility

SANA vs. SMH - Volatility Comparison

Sana Biotechnology, Inc. (SANA) has a higher volatility of 30.23% compared to VanEck Vectors Semiconductor ETF (SMH) at 12.33%. This indicates that SANA's price experiences larger fluctuations and is considered to be riskier than SMH based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


0.00%20.00%40.00%60.00%80.00%100.00%SeptemberOctoberNovemberDecember2025February
30.23%
12.33%
SANA
SMH
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Disclaimer

The information contained herein does not constitute investment advice and made available for educational purposes only. Prices and returns on equities are listed without consideration of fees, commissions, taxes, penalties, or interest payable due to purchasing, holding, or selling.

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