ROIV vs. SDGR

Last updated Jun 4, 2026

ROIV (Roivant Sciences Ltd.) and SDGR (Schrodinger, Inc.) are both stocks. Both are in the Healthcare sector — ROIV in Biotechnology, SDGR in Health Information Services. Over the past 3 years, ROIV returned 44.87%/yr vs -25.18%/yr for SDGR. At a 0.36 correlation, their price movements are largely independent.

Performance

ROIV vs. SDGR - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Roivant Sciences Ltd. (ROIV) and Schrodinger, Inc. (SDGR). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, ROIV achieves a 32.26% return, which is significantly higher than SDGR's -16.50% return.

ROIV

• 1D: 1.59%
• 1M: 1.20%
• YTD: 32.26%
• 6M: 38.65%
• 1Y: 155.22%
• 3Y*: 44.87%
• 5Y*: —
• 10Y*: —

SDGR

• 1D: -0.07%
• 1M: 15.74%
• YTD: -16.50%
• 6M: -15.84%
• 1Y: -34.80%
• 3Y*: -25.18%
• 5Y*: -26.96%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

ROIV vs. SDGR - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
ROIV Roivant Sciences Ltd.	32.26%	83.43%	5.34%	40.55%	-20.73%	7.81%
SDGR Schrodinger, Inc.	-16.50%	-7.31%	-46.12%	91.55%	-46.34%	-35.49%

Correlation

The correlation between ROIV and SDGR is 0.29, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.29
Correlation (3Y) Calculated over the trailing 3-year period	0.37
Correlation (All Time) Calculated using the full available price history since Oct 4, 2021	0.36

Fundamentals

Market Cap ROIV : $19.91B SDGR : $1.10B
EPS ROIV : -$0.44 SDGR : -$1.41
PS Ratio ROIV : 2.39K SDGR : 4.31
PB Ratio ROIV : 3.76 SDGR : 3.52
Total Revenue (TTM) ROIV : $8.26M SDGR : $254.91M
Gross Profit (TTM) ROIV : $6.98M SDGR : $141.04M
EBITDA (TTM) ROIV : -$316.38M SDGR : -$85.22M

Return for Risk

ROIV vs. SDGR — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

ROIV

ROIV Risk / Return Rank: 98
ROIV Sharpe Ratio Rank: 97
ROIV Sortino Ratio Rank: 98
ROIV Omega Ratio Rank: 96
ROIV Calmar Ratio Rank: 98
ROIV Martin Ratio Rank: 98

SDGR

SDGR Risk / Return Rank: 17
SDGR Sharpe Ratio Rank: 13
SDGR Sortino Ratio Rank: 15
SDGR Omega Ratio Rank: 16
SDGR Calmar Ratio Rank: 19
SDGR Martin Ratio Rank: 23

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

ROIV vs. SDGR - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Roivant Sciences Ltd. (ROIV) and Schrodinger, Inc. (SDGR). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	ROIV	SDGR	Difference
Sharpe ratio Return per unit of total volatility	3.79	-0.66	+4.45
Sortino ratio Return per unit of downside risk	5.47	-0.76	+6.23
Omega ratio Gain probability vs. loss probability	1.64	0.91	+0.72
Calmar ratio Return relative to maximum drawdown	12.17	-0.60	+12.76
Martin ratio Return relative to average drawdown	39.09	-0.91	+40.00
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

ROIV vs. SDGR - Sharpe Ratio Comparison

The current ROIV Sharpe Ratio is 3.79, which is higher than the SDGR Sharpe Ratio of -0.66. The chart below compares the historical Sharpe Ratios of ROIV and SDGR, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	ROIV	SDGR	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	3.79	-0.66	+4.45
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.43	—
Sharpe Ratio (All Time) Calculated using the full available price history	0.45	-0.14	+0.59

Drawdowns

ROIV vs. SDGR - Drawdown Comparison

The maximum ROIV drawdown since its inception was -79.22%, smaller than the maximum SDGR drawdown of -90.21%. Use the drawdown chart below to compare losses from any high point for ROIV and SDGR.

Drawdown Indicators

	ROIV	SDGR	Difference
Max Drawdown Largest peak-to-trough decline	-79.22%	-90.21%	+10.99%
Max Drawdown (1Y) Largest decline over 1 year	-12.84%	-58.52%	+45.68%
Max Drawdown (3Y) Largest decline over 3 years	-36.47%	-80.01%	+43.54%
Max Drawdown (5Y) Largest decline over 5 years	—	-85.95%	—
Current Drawdown Current decline from peak	-11.45%	-86.80%	+75.35%
Average Drawdown Average peak-to-trough decline	-27.52%	-64.02%	+36.50%
Ulcer Index Depth and duration of drawdowns from previous peaks	3.99%	38.46%	-34.47%

Volatility

ROIV vs. SDGR - Volatility Comparison

Roivant Sciences Ltd. (ROIV) has a higher volatility of 16.81% compared to Schrodinger, Inc. (SDGR) at 15.91%. This indicates that ROIV's price experiences larger fluctuations and is considered to be riskier than SDGR based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	ROIV	SDGR	Difference
Volatility (1M) Calculated over the trailing 1-month period	16.81%	15.91%	+0.90%
Volatility (6M) Calculated over the trailing 6-month period	34.03%	37.14%	-3.11%
Volatility (1Y) Calculated over the trailing 1-year period	41.25%	52.90%	-11.65%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	60.66%	63.18%	-2.52%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	60.66%	69.86%	-9.20%

Dividends

ROIV vs. SDGR - Dividend Comparison

Neither ROIV nor SDGR has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both ROIV and SDGR in my portfolio?

ROIV and SDGR have a correlation of 0.29, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, ROIV or SDGR?

ROIV has higher volatility (16.81%) compared to SDGR (15.91%). In terms of maximum drawdown, ROIV dropped -79.22% vs SDGR's -90.21%.

Which has better risk-adjusted returns?

ROIV currently has the higher Sharpe Ratio (3.79 vs -0.66), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.