QLYS vs. ISRG

Last updated Apr 2, 2026

Compare and contrast key facts about Qualys, Inc. (QLYS) and Intuitive Surgical, Inc. (ISRG).

Performance

QLYS vs. ISRG - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Qualys, Inc. (QLYS) and Intuitive Surgical, Inc. (ISRG). The values are adjusted to include any dividend payments, if applicable.

QLYS vs. ISRG - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
QLYS Qualys, Inc.	-35.14%	-5.22%	-28.56%	74.89%	-18.21%	12.60%	46.18%	11.55%	25.93%	87.52%
ISRG Intuitive Surgical, Inc.	-17.99%	8.51%	54.72%	27.14%	-26.15%	31.76%	38.39%	23.43%	31.23%	72.64%

Fundamentals

Market Cap QLYS : $3.12B ISRG : $167.39B
EPS QLYS : $5.46 ISRG : $7.89
PE Ratio QLYS : 15.79 ISRG : 58.89
PEG Ratio QLYS : 0.48 ISRG : 3.60
PS Ratio QLYS : 4.68 ISRG : 16.71
PB Ratio QLYS : 5.55 ISRG : 9.39
Total Revenue (TTM) QLYS : $669.13M ISRG : $10.06B
Gross Profit (TTM) QLYS : $554.36M ISRG : $6.64B
EBITDA (TTM) QLYS : $238.63M ISRG : $3.62B

Returns By Period

In the year-to-date period, QLYS achieves a -35.14% return, which is significantly lower than ISRG's -17.99% return. Over the past 10 years, QLYS has underperformed ISRG with an annualized return of 12.84%, while ISRG has yielded a comparatively higher 21.29% annualized return.

QLYS

• 1D: -1.87%
• 1M: -8.86%
• YTD: -35.14%
• 6M: -34.38%
• 1Y: -33.00%
• 3Y*: -12.80%
• 5Y*: -3.66%
• 10Y*: 12.84%

ISRG

• 1D: 0.75%
• 1M: -6.41%
• YTD: -17.99%
• 6M: 6.03%
• 1Y: -6.43%
• 3Y*: 22.05%
• 5Y*: 13.26%
• 10Y*: 21.29%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

QLYS vs. ISRG — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

QLYS

QLYS Risk / Return Rank: 9
QLYS Sharpe Ratio Rank: 8
QLYS Sortino Ratio Rank: 9
QLYS Omega Ratio Rank: 9
QLYS Calmar Ratio Rank: 16
QLYS Martin Ratio Rank: 2

ISRG

ISRG Risk / Return Rank: 31
ISRG Sharpe Ratio Rank: 32
ISRG Sortino Ratio Rank: 28
ISRG Omega Ratio Rank: 28
ISRG Calmar Ratio Rank: 33
ISRG Martin Ratio Rank: 33

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

QLYS vs. ISRG - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Qualys, Inc. (QLYS) and Intuitive Surgical, Inc. (ISRG). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	QLYS	ISRG	Difference
Sharpe ratio Return per unit of total volatility	-0.81	-0.19	-0.62
Sortino ratio Return per unit of downside risk	-1.12	-0.05	-1.07
Omega ratio Gain probability vs. loss probability	0.85	0.99	-0.14
Calmar ratio Return relative to maximum drawdown	-0.71	-0.26	-0.45
Martin ratio Return relative to average drawdown	-1.86	-0.48	-1.37
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

QLYS vs. ISRG - Sharpe Ratio Comparison

The current QLYS Sharpe Ratio is -0.81, which is lower than the ISRG Sharpe Ratio of -0.19. The chart below compares the historical Sharpe Ratios of QLYS and ISRG, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	QLYS	ISRG	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.81	-0.19	-0.62
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.09	0.40	-0.50
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	0.33	0.67	-0.33
Sharpe Ratio (All Time) Calculated using the full available price history	0.34	0.49	-0.15

Correlation

The correlation between QLYS and ISRG is 0.38, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

QLYS vs. ISRG - Dividend Comparison

Neither QLYS nor ISRG has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

QLYS vs. ISRG - Drawdown Comparison

The maximum QLYS drawdown since its inception was -68.48%, smaller than the maximum ISRG drawdown of -82.26%. Use the drawdown chart below to compare losses from any high point for QLYS and ISRG.

Drawdown Indicators

	QLYS	ISRG	Difference
Max Drawdown Largest peak-to-trough decline	-68.48%	-82.26%	+13.78%
Max Drawdown (1Y) Largest decline over 1 year	-44.32%	-24.09%	-20.23%
Max Drawdown (5Y) Largest decline over 5 years	-58.41%	-49.90%	-8.51%
Max Drawdown (10Y) Largest decline over 10 years	-58.41%	-49.90%	-8.51%
Current Drawdown Current decline from peak	-58.13%	-23.92%	-34.21%
Average Drawdown Average peak-to-trough decline	-20.40%	-21.24%	+0.84%
Ulcer Index Depth and duration of drawdowns from previous peaks	17.00%	12.86%	+4.14%

Volatility

QLYS vs. ISRG - Volatility Comparison

Qualys, Inc. (QLYS) has a higher volatility of 11.47% compared to Intuitive Surgical, Inc. (ISRG) at 6.54%. This indicates that QLYS's price experiences larger fluctuations and is considered to be riskier than ISRG based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	QLYS	ISRG	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.47%	6.54%	+4.93%
Volatility (6M) Calculated over the trailing 6-month period	34.50%	22.05%	+12.45%
Volatility (1Y) Calculated over the trailing 1-year period	40.88%	33.82%	+7.06%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	38.77%	33.01%	+5.76%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	38.47%	32.09%	+6.38%

Financials

QLYS vs. ISRG - Profitability Comparison

The chart below illustrates the profitability comparison between Qualys, Inc. and Intuitive Surgical, Inc. over time, highlighting three key metrics: Gross Profit Margin, Operating Margin, and Net Profit Margin.

QLYS - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Qualys, Inc. reported a gross profit of 146.12M and revenue of 175.28M. Therefore, the gross margin over that period was 83.4%.

ISRG - Gross Margin

Gross margin is calculated as gross profit divided by revenue. For the three months ending on Apr 2026, Intuitive Surgical, Inc. reported a gross profit of 1.90B and revenue of 2.87B. Therefore, the gross margin over that period was 66.4%.

QLYS - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Qualys, Inc. reported an operating income of 58.84M and revenue of 175.28M, resulting in an operating margin of 33.6%.

ISRG - Operating Margin

Operating margin is calculated as operating income divided by revenue. For the three months ending on Apr 2026, Intuitive Surgical, Inc. reported an operating income of 864.30M and revenue of 2.87B, resulting in an operating margin of 30.2%.

QLYS - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Qualys, Inc. reported a net income of 53.15M and revenue of 175.28M, resulting in a net margin of 30.3%.

ISRG - Net Margin

Net margin is calculated as net income divided by revenue. For the three months ending on Apr 2026, Intuitive Surgical, Inc. reported a net income of 794.80M and revenue of 2.87B, resulting in a net margin of 27.7%.