PRFX vs. FNDA

Last updated Aug 1, 2026

PRFX (PainReform Ltd.) is a stock, while FNDA (Schwab Fundamental U.S. Small Company ETF) is Small Cap Blend Equities fund tracking the RAFI Fundamental High Liquidity U.S. Small Index. Over the past 5 years, PRFX returned -80.40%/yr vs 9.29%/yr for FNDA. Their 0.21 correlation means their historical movements had little consistent relationship.

Performance

PRFX vs. FNDA - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in PainReform Ltd. (PRFX) and Schwab Fundamental U.S. Small Company ETF (FNDA). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, PRFX achieves a -68.84% return, which is significantly lower than FNDA's 20.40% return.

PRFX

• 1D: -2.91%
• 1M: -26.47%
• 6M: -70.28%
• YTD: -68.84%
• 1Y: -84.85%
• 3Y*: -89.46%
• 5Y*: -80.40%
• 10Y*: —
• ALL TIME*: -78.69%

FNDA

• 1D: 1.63%
• 1M: 0.40%
• 6M: 12.61%
• YTD: 20.40%
• 1Y: 33.05%
• 3Y*: 14.30%
• 5Y*: 9.29%
• 10Y*: 10.85%
• ALL TIME*: 10.47%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Liquidity Comparison

Position	Avg. Volume Value (2W)	Avg. Volume Value (1M)	Avg. Volume Value (3M)
FNDA Schwab Fundamental U.S. Small Company ETF	$15.68M	$15.22M	$42.48M
PRFX PainReform Ltd.	$215.58K	$213.61K	$5.80M

PRFX vs. FNDA - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
PRFX PainReform Ltd.	-68.84%	-80.87%	-94.92%	-33.37%	-68.97%	-70.25%	-42.32%
FNDA Schwab Fundamental U.S. Small Company ETF	20.40%	7.44%	9.00%	20.29%	-14.83%	31.12%	24.56%

Correlation

The correlation between PRFX and FNDA is 0.30, which is low. Their historical price movements had little consistent relationship.

	Correlation
Correlation (1Y) Focuses on recent behavior, but can change the most.	0.30
Correlation (3Y) Balances recent behavior with more history.	0.27
Correlation (5Y) Shows whether the relationship held over a longer period.	0.22
Correlation (All Time) Calculated using the full available price history since Sep 1, 2020	0.21

Return for Risk

PRFX vs. FNDA — Risk / Return Rank

Compare historical risk-adjusted metric ranks over the past 12 months.

PRFX

PRFX Risk / Return Rank: 16
PRFX Sharpe Ratio Rank: 24
PRFX Sortino Ratio Rank: 18
PRFX Omega Ratio Rank: 20
PRFX Calmar Ratio Rank: 5
PRFX Martin Ratio Rank: 13

FNDA

FNDA Risk / Return Rank: 83
FNDA Sharpe Ratio Rank: 82
FNDA Sortino Ratio Rank: 84
FNDA Omega Ratio Rank: 79
FNDA Calmar Ratio Rank: 87
FNDA Martin Ratio Rank: 83

The rank (0–100) uses a weighted average of the Sharpe, Sortino, Omega, Calmar, and Martin percentile ranks for the trailing 12 months. Higher means stronger historical risk-adjusted performance within the peer group.

PRFX vs. FNDA - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for PainReform Ltd. (PRFX) and Schwab Fundamental U.S. Small Company ETF (FNDA). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	PRFX	FNDA	Difference
Sharpe ratio: Return per unit of total volatility	-0.44	1.96	-2.40
Sortino ratio: Return per unit of downside risk	-0.65	2.84	-3.49
Omega ratio: Gain probability vs. loss probability	0.93	1.34	-0.41
Calmar ratio: Return relative to maximum drawdown	-0.94	3.55	-4.49
Martin ratio: Return relative to average drawdown	-1.25	11.61	-12.87

PRFX vs. FNDA - Sharpe Ratio Comparison

The current PRFX Sharpe Ratio is -0.44, which is lower than the FNDA Sharpe Ratio of 1.96. The chart below compares the historical Sharpe Ratios of PRFX and FNDA, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

PRFX vs. FNDA - Drawdown Comparison

The maximum PRFX drawdown since its inception was -99.99%, which is greater than FNDA's maximum drawdown of -44.64%. Use the drawdown chart below to compare losses from any high point for PRFX and FNDA.

Drawdown Indicators

	PRFX	FNDA	Difference
Max Drawdown Largest peak-to-trough decline	-99.99%	-44.64%	-55.35%
Max Drawdown (1Y) Largest decline over 1 year	-91.64%	-9.36%	-82.28%
Max Drawdown (3Y) Largest decline over 3 years	-99.88%	-25.92%	-73.96%
Max Drawdown (5Y) Largest decline over 5 years	-99.97%	-25.92%	-74.05%
Max Drawdown (10Y) Largest decline over 10 years	—	-44.64%	—
Current Drawdown Current decline from peak	-99.99%	-0.76%	-99.23%
Average Drawdown Average peak-to-trough decline	-86.10%	-6.62%	-79.48%
Ulcer Index Depth and duration of drawdowns from previous peaks	68.52%	2.85%	+65.67%

Volatility

PRFX vs. FNDA - Volatility Comparison

PainReform Ltd. (PRFX) has a higher volatility of 21.54% compared to Schwab Fundamental U.S. Small Company ETF (FNDA) at 3.72%. This indicates that PRFX's price experiences larger fluctuations and is considered to be riskier than FNDA based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PRFX	FNDA	Difference
Volatility (1M) Calculated over the trailing 1-month period	21.54%	3.72%	+17.82%
Volatility (6M) Calculated over the trailing 6-month period	128.31%	11.88%	+116.43%
Volatility (1Y) Calculated over the trailing 1-year period	196.58%	16.98%	+179.60%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	280.70%	20.73%	+259.97%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	260.85%	22.32%	+238.53%

Dividends

PRFX vs. FNDA - Dividend Comparison

PRFX has not paid dividends to shareholders, while FNDA's dividend yield for the trailing twelve months is around 1.10%.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
FNDA Schwab Fundamental U.S. Small Company ETF	1.10%	1.22%	1.53%	1.37%	1.38%	1.15%	1.31%	1.38%	1.64%	1.30%	1.18%	1.33%
PRFX PainReform Ltd.	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both PRFX and FNDA in my portfolio?

PRFX and FNDA have a correlation of 0.30, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, PRFX or FNDA?

PRFX has higher volatility (21.54%) compared to FNDA (3.72%). In terms of maximum drawdown, PRFX dropped -99.99% vs FNDA's -44.64%.

Which has better risk-adjusted returns?

FNDA currently has the higher Sharpe Ratio (1.96 vs -0.44), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.