PCVX vs. ZS

Last updated Apr 1, 2026

Compare and contrast key facts about Vaxcyte, Inc. (PCVX) and Zscaler, Inc. (ZS).

Performance

PCVX vs. ZS - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Vaxcyte, Inc. (PCVX) and Zscaler, Inc. (ZS). The values are adjusted to include any dividend payments, if applicable.

PCVX vs. ZS - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
PCVX Vaxcyte, Inc.	25.94%	-43.64%	30.35%	30.97%	101.56%	-10.46%	1.61%
ZS Zscaler, Inc.	-37.63%	24.67%	-18.57%	98.00%	-65.18%	60.90%	94.90%

Fundamentals

EPS PCVX : -$4.83 ZS : -$0.43
Total Revenue (TTM) PCVX : $0.00 ZS : $3.00B
Gross Profit (TTM) PCVX : -$4.99M ZS : $2.30B
EBITDA (TTM) PCVX : -$599.85M ZS : $56.95M

Returns By Period

In the year-to-date period, PCVX achieves a 25.94% return, which is significantly higher than ZS's -37.63% return.

PCVX

• 1D: 5.73%
• 1M: -5.88%
• YTD: 25.94%
• 6M: 61.33%
• 1Y: 53.89%
• 3Y*: 15.74%
• 5Y*: 22.66%
• 10Y*: —

ZS

• 1D: 2.21%
• 1M: -4.56%
• YTD: -37.63%
• 6M: -53.18%
• 1Y: -29.30%
• 3Y*: 6.29%
• 5Y*: -4.41%
• 10Y*: —

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

PCVX vs. ZS — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

PCVX

PCVX Risk / Return Rank: 47
PCVX Sharpe Ratio Rank: 73
PCVX Sortino Ratio Rank: 69
PCVX Omega Ratio Rank: 66
PCVX Calmar Ratio Rank: 19
PCVX Martin Ratio Rank: 10

ZS

ZS Risk / Return Rank: 18
ZS Sharpe Ratio Rank: 14
ZS Sortino Ratio Rank: 17
ZS Omega Ratio Rank: 16
ZS Calmar Ratio Rank: 25
ZS Martin Ratio Rank: 18

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

PCVX vs. ZS - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Vaxcyte, Inc. (PCVX) and Zscaler, Inc. (ZS). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	PCVX	ZS	Difference
Sharpe ratio Return per unit of total volatility	0.94	-0.64	+1.58
Sortino ratio Return per unit of downside risk	1.54	-0.68	+2.22
Omega ratio Gain probability vs. loss probability	1.19	0.90	+0.29
Calmar ratio Return relative to maximum drawdown	-0.63	-0.53	-0.10
Martin ratio Return relative to average drawdown	-1.49	-1.24	-0.25
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

PCVX vs. ZS - Sharpe Ratio Comparison

The current PCVX Sharpe Ratio is 0.94, which is higher than the ZS Sharpe Ratio of -0.64. The chart below compares the historical Sharpe Ratios of PCVX and ZS, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	PCVX	ZS	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.94	-0.64	+1.58
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.36	-0.08	+0.44
Sharpe Ratio (All Time) Calculated using the full available price history	0.22	0.35	-0.12

Correlation

The correlation between PCVX and ZS is 0.22, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

PCVX vs. ZS - Dividend Comparison

Neither PCVX nor ZS has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

PCVX vs. ZS - Drawdown Comparison

The maximum PCVX drawdown since its inception was -76.22%, roughly equal to the maximum ZS drawdown of -76.41%. Use the drawdown chart below to compare losses from any high point for PCVX and ZS.

Drawdown Indicators

	PCVX	ZS	Difference
Max Drawdown Largest peak-to-trough decline	-76.22%	-76.41%	+0.19%
Max Drawdown (1Y) Largest decline over 1 year	-20.60%	-60.40%	+39.80%
Max Drawdown (5Y) Largest decline over 5 years	-76.22%	-76.41%	+0.19%
Current Drawdown Current decline from peak	-50.73%	-61.96%	+11.23%
Average Drawdown Average peak-to-trough decline	-37.62%	-31.96%	-5.66%
Ulcer Index Depth and duration of drawdowns from previous peaks	10.97%	26.13%	-15.16%

Volatility

PCVX vs. ZS - Volatility Comparison

The current volatility for Vaxcyte, Inc. (PCVX) is 11.40%, while Zscaler, Inc. (ZS) has a volatility of 14.01%. This indicates that PCVX experiences smaller price fluctuations and is considered to be less risky than ZS based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	PCVX	ZS	Difference
Volatility (1M) Calculated over the trailing 1-month period	11.40%	14.01%	-2.61%
Volatility (6M) Calculated over the trailing 6-month period	33.47%	36.32%	-2.85%
Volatility (1Y) Calculated over the trailing 1-year period	73.60%	46.18%	+27.42%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	64.02%	53.25%	+10.77%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	66.63%	57.02%	+9.61%

Financials