PALI vs. MCRB
PALI (Palisade Bio, Inc.) and MCRB (Seres Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, PALI returned -69.33%/yr vs -30.79%/yr for MCRB. Their 0.17 correlation means their historical movements had little consistent relationship.
Performance
PALI vs. MCRB - Performance Comparison
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Returns By Period
In the year-to-date period, PALI achieves a -19.36% return, which is significantly higher than MCRB's -67.54% return. Over the past 10 years, PALI has underperformed MCRB with an annualized return of -69.33%, while MCRB has yielded a comparatively higher -30.79% annualized return.
PALI
- 1D
- -3.32%
- 1M
- -9.76%
- 6M
- 27.18%
- YTD
- -19.36%
- 1Y
- 87.62%
- 3Y*
- -60.94%
- 5Y*
- -75.61%
- 10Y*
- -69.33%
- ALL TIME*
- -49.91%
MCRB
- 1D
- 1.05%
- 1M
- -37.60%
- 6M
- -67.63%
- YTD
- -67.54%
- 1Y
- -65.48%
- 3Y*
- -63.16%
- 5Y*
- -49.15%
- 10Y*
- -30.79%
- ALL TIME*
- -34.94%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
| $248.61K | $577.47K | $564.10K | |
| $4.73M | $5.83M | $6.50M |
PALI vs. MCRB - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
PALI Palisade Bio, Inc. | -19.36% | 42.42% | -81.36% | -88.65% | -92.00% | -75.38% | -11.11% | -84.19% | -81.80% | -51.61% |
MCRB Seres Therapeutics, Inc. | -67.54% | -10.47% | -40.64% | -75.00% | -32.77% | -66.00% | 610.14% | -23.67% | -55.42% | 2.42% |
Correlation
The correlation between PALI and MCRB is 0.24, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.24 |
Correlation (3Y) Balances recent behavior with more history. | 0.17 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.19 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.16 |
Correlation (All Time) Calculated using the full available price history since Jun 26, 2015 | 0.17 |
Fundamentals
PALI:
$328.93M
MCRB:
$46.77M
PALI:
-$0.27
MCRB:
-$5.17
PALI:
3.12
MCRB:
1.75
PALI:
$0.00
MCRB:
$1.15M
PALI:
$0.00
MCRB:
$183.00K
PALI:
-$26.58M
MCRB:
-$47.68M
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Return for Risk
PALI vs. MCRB — Risk / Return Rank
PALI
MCRB
PALI vs. MCRB - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Palisade Bio, Inc. (PALI) and Seres Therapeutics, Inc. (MCRB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| PALI | MCRB | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.45 | ||
| Sortino ratioReturn per unit of downside risk | +2.77 | ||
| Omega ratioGain probability vs. loss probability | 1.22 | 0.88 | +0.33 |
| Calmar ratioReturn relative to maximum drawdown | 1.79 | -0.79 | +2.58 |
| Martin ratioReturn relative to average drawdown | 3.23 | -1.19 | +4.42 |
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Drawdowns
PALI vs. MCRB - Drawdown Comparison
The maximum PALI drawdown since its inception was -100.00%, roughly equal to the maximum MCRB drawdown of -99.55%. Use the drawdown chart below to compare losses from any high point for PALI and MCRB.
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Drawdown Indicators
| PALI | MCRB | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -100.00% | -99.55% | -0.45% |
Max Drawdown (1Y)Largest decline over 1 year | -48.17% | -83.76% | +35.59% |
Max Drawdown (3Y)Largest decline over 3 years | -98.27% | -95.41% | -2.86% |
Max Drawdown (5Y)Largest decline over 5 years | -99.98% | -97.97% | -2.01% |
Max Drawdown (10Y)Largest decline over 10 years | -100.00% | -99.38% | -0.62% |
Current DrawdownCurrent decline from peak | -100.00% | -99.53% | -0.47% |
Average DrawdownAverage peak-to-trough decline | -76.46% | -81.63% | +5.17% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 26.64% | 55.49% | -28.85% |
Volatility
PALI vs. MCRB - Volatility Comparison
The current volatility for Palisade Bio, Inc. (PALI) is 17.14%, while Seres Therapeutics, Inc. (MCRB) has a volatility of 21.35%. This indicates that PALI experiences smaller price fluctuations and is considered to be less risky than MCRB based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PALI | MCRB | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 17.14% | 21.35% | -4.21% |
Volatility (6M)Calculated over the trailing 6-month period | 59.08% | 70.96% | -11.88% |
Volatility (1Y)Calculated over the trailing 1-year period | 115.38% | 94.56% | +20.82% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 145.64% | 101.44% | +44.20% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 140.93% | 152.71% | -11.78% |
Dividends
PALI vs. MCRB - Dividend Comparison
Neither PALI nor MCRB has paid dividends to shareholders.
Financials
PALI vs. MCRB - Financials Comparison
This section allows you to compare key financial metrics between Palisade Bio, Inc. and Seres Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
PALI and MCRB have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
MCRB has higher volatility (21.35%) compared to PALI (17.14%). In terms of maximum drawdown, PALI dropped -100.00% vs MCRB's -99.55%.
PALI currently has the higher Sharpe Ratio (0.75 vs -0.70), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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