PALI vs. MCRB
PALI (Palisade Bio, Inc.) and MCRB (Seres Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. Over the past 10 years, PALI returned -71.09%/yr vs -36.84%/yr for MCRB. At a 0.16 correlation, their price movements are largely independent.
Performance
PALI vs. MCRB - Performance Comparison
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Returns By Period
In the year-to-date period, PALI achieves a -25.96% return, which is significantly higher than MCRB's -55.44% return. Over the past 10 years, PALI has underperformed MCRB with an annualized return of -71.09%, while MCRB has yielded a comparatively higher -36.84% annualized return.
PALI
- 1D
- -9.84%
- 1M
- -12.56%
- YTD
- -25.96%
- 6M
- -3.33%
- 1Y
- 149.75%
- 3Y*
- -57.30%
- 5Y*
- -77.22%
- 10Y*
- -71.09%
MCRB
- 1D
- -3.21%
- 1M
- -14.12%
- YTD
- -55.44%
- 6M
- -60.20%
- 1Y
- -19.44%
- 3Y*
- -58.86%
- 5Y*
- -55.39%
- 10Y*
- -36.84%
PALI vs. MCRB - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
PALI Palisade Bio, Inc. | -25.96% | 42.42% | -81.36% | -88.65% | -92.00% | -75.38% | -11.11% | -84.19% | -81.80% | -51.61% |
MCRB Seres Therapeutics, Inc. | -55.44% | -10.47% | -40.64% | -75.00% | -32.77% | -66.00% | 610.14% | -23.67% | -55.42% | 2.42% |
Correlation
The correlation between PALI and MCRB is 0.21, which is low. Their price movements are largely independent, making them effective diversification partners.
| Correlation | |
|---|---|
Correlation (1Y) Calculated over the trailing 1-year period | 0.21 |
Correlation (3Y) Calculated over the trailing 3-year period | 0.16 |
Correlation (5Y) Calculated over the trailing 5-year period | 0.18 |
Correlation (10Y) Calculated over the trailing 10-year period | 0.16 |
Correlation (All Time) Calculated using the full available price history since Jun 29, 2015 | 0.16 |
Fundamentals
PALI:
$364.82M
MCRB:
$63.53M
PALI:
-$0.35
MCRB:
-$5.22
PALI:
2.86
MCRB:
2.40
PALI:
$0.00
MCRB:
$1.15M
PALI:
$0.00
MCRB:
$183.00K
PALI:
-$26.58M
MCRB:
-$47.68M
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Return for Risk
PALI vs. MCRB — Risk / Return Rank
PALI
MCRB
PALI vs. MCRB - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Palisade Bio, Inc. (PALI) and Seres Therapeutics, Inc. (MCRB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
| PALI | MCRB | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.34 | ||
| Sortino ratioReturn per unit of downside risk | +1.88 | ||
| Omega ratioGain probability vs. loss probability | 1.28 | 1.09 | +0.19 |
| Calmar ratioReturn relative to maximum drawdown | 2.77 | -0.11 | +2.89 |
| Martin ratioReturn relative to average drawdown | 5.96 | -0.19 | +6.14 |
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month. | |||
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Sharpe Ratios by Period
| PALI | MCRB | Difference | |
|---|---|---|---|
Sharpe Ratio (1Y)Calculated over the trailing 1-year period | 1.25 | -0.09 | +1.34 |
Sharpe Ratio (5Y)Calculated over the trailing 5-year period | -0.53 | -0.53 | 0.00 |
Sharpe Ratio (10Y)Calculated over the trailing 10-year period | -0.51 | -0.24 | -0.27 |
Sharpe Ratio (All Time)Calculated using the full available price history | -0.45 | -0.25 | -0.20 |
Drawdowns
PALI vs. MCRB - Drawdown Comparison
The maximum PALI drawdown since its inception was -100.00%, roughly equal to the maximum MCRB drawdown of -99.36%. Use the drawdown chart below to compare losses from any high point for PALI and MCRB.
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Drawdown Indicators
| PALI | MCRB | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -100.00% | -99.36% | -0.64% |
Max Drawdown (1Y)Largest decline over 1 year | -56.53% | -76.84% | +20.31% |
Max Drawdown (3Y)Largest decline over 3 years | -98.44% | -94.64% | -3.80% |
Max Drawdown (5Y)Largest decline over 5 years | -99.98% | -98.64% | -1.34% |
Max Drawdown (10Y)Largest decline over 10 years | -100.00% | -99.12% | -0.88% |
Current DrawdownCurrent decline from peak | -100.00% | -99.36% | -0.64% |
Average DrawdownAverage peak-to-trough decline | -76.29% | -81.41% | +5.12% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 26.26% | 46.42% | -20.16% |
Volatility
PALI vs. MCRB - Volatility Comparison
Palisade Bio, Inc. (PALI) has a higher volatility of 23.25% compared to Seres Therapeutics, Inc. (MCRB) at 14.03%. This indicates that PALI's price experiences larger fluctuations and is considered to be riskier than MCRB based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
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Volatility by Period
| PALI | MCRB | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 23.25% | 14.03% | +9.22% |
Volatility (6M)Calculated over the trailing 6-month period | 68.12% | 66.69% | +1.43% |
Volatility (1Y)Calculated over the trailing 1-year period | 125.43% | 102.45% | +22.98% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 145.73% | 104.70% | +41.03% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 140.79% | 154.15% | -13.36% |
Dividends
PALI vs. MCRB - Dividend Comparison
Neither PALI nor MCRB has paid dividends to shareholders.
Financials
PALI vs. MCRB - Financials Comparison
This section allows you to compare key financial metrics between Palisade Bio, Inc. and Seres Therapeutics, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
Frequently Asked Questions
PALI and MCRB have a correlation of 0.21, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
PALI has higher volatility (23.25%) compared to MCRB (14.03%). In terms of maximum drawdown, PALI dropped -100.00% vs MCRB's -99.36%.
PALI currently has the higher Sharpe Ratio (1.25 vs -0.09), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
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