OM vs. SGMO

Last updated Jun 5, 2026

OM (Outset Medical, Inc.) and SGMO (Sangamo Therapeutics, Inc.) are both stocks. Both are in the Healthcare sector — OM in Medical Devices, SGMO in Biotechnology. Over the past 5 years, OM returned -63.10%/yr vs -54.57%/yr for SGMO. At a 0.24 correlation, their price movements are largely independent.

Performance

OM vs. SGMO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Outset Medical, Inc. (OM) and Sangamo Therapeutics, Inc. (SGMO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, OM achieves a 27.49% return, which is significantly higher than SGMO's -49.85% return.

OM

• 1D: 2.83%
• 1M: -0.84%
• YTD: 27.49%
• 6M: 0.21%
• 1Y: -75.52%
• 3Y*: -75.57%
• 5Y*: -63.10%
• 10Y*: —

SGMO

• 1D: -2.57%
• 1M: 89.08%
• YTD: -49.85%
• 6M: -60.26%
• 1Y: -57.19%
• 3Y*: -43.37%
• 5Y*: -54.57%
• 10Y*: -30.04%

*Multi-year figures are annualized to reflect compound growth (CAGR)

OM vs. SGMO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
OM Outset Medical, Inc.	27.49%	-77.72%	-79.48%	-79.05%	-43.98%	-18.91%	-6.33%
SGMO Sangamo Therapeutics, Inc.	-49.85%	-58.82%	87.74%	-82.70%	-58.13%	-51.94%	46.25%

Correlation

The correlation between OM and SGMO is 0.24, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.24
Correlation (3Y) Calculated over the trailing 3-year period	0.20
Correlation (5Y) Calculated over the trailing 5-year period	0.25
Correlation (All Time) Calculated using the full available price history since Sep 16, 2020	0.24

Fundamentals

Market Cap OM : $86.90M SGMO : $82.07M
EPS OM : -$4.17 SGMO : -$0.38
PS Ratio OM : 0.72 SGMO : 1.96
Total Revenue (TTM) OM : $117.59M SGMO : $34.56M
Gross Profit (TTM) OM : $47.78M SGMO : $25.51M
EBITDA (TTM) OM : -$62.73M SGMO : -$106.29M

Return for Risk

OM vs. SGMO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

OM

OM Risk / Return Rank: 10
OM Sharpe Ratio Rank: 9
OM Sortino Ratio Rank: 9
OM Omega Ratio Rank: 8
OM Calmar Ratio Rank: 7
OM Martin Ratio Rank: 15

SGMO

SGMO Risk / Return Rank: 22
SGMO Sharpe Ratio Rank: 21
SGMO Sortino Ratio Rank: 30
SGMO Omega Ratio Rank: 30
SGMO Calmar Ratio Rank: 17
SGMO Martin Ratio Rank: 10

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

OM vs. SGMO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Outset Medical, Inc. (OM) and Sangamo Therapeutics, Inc. (SGMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	OM	SGMO	Difference
Sharpe ratio: Return per unit of total volatility	-0.79	-0.46	-0.33
Sortino ratio: Return per unit of downside risk	-1.16	-0.04	-1.12
Omega ratio: Gain probability vs. loss probability	0.83	1.00	-0.16
Calmar ratio: Return relative to maximum drawdown	-0.89	-0.66	-0.22
Martin ratio: Return relative to average drawdown	-1.20	-1.35	+0.16
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

OM vs. SGMO - Sharpe Ratio Comparison

The current OM Sharpe Ratio is -0.79, which is lower than the SGMO Sharpe Ratio of -0.46. The chart below compares the historical Sharpe Ratios of OM and SGMO, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Sharpe Ratios by Period

	OM	SGMO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.79	-0.46	-0.33
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.63	-0.49	-0.15
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.31	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.63	-0.17	-0.46

Drawdowns

OM vs. SGMO - Drawdown Comparison

The maximum OM drawdown since its inception was -99.67%, roughly equal to the maximum SGMO drawdown of -99.80%. Use the drawdown chart below to compare losses from any high point for OM and SGMO.

Drawdown Indicators

	OM	SGMO	Difference
Max Drawdown Largest peak-to-trough decline	-99.67%	-99.80%	+0.13%
Max Drawdown (1Y) Largest decline over 1 year	-85.12%	-86.32%	+1.20%
Max Drawdown (3Y) Largest decline over 3 years	-99.11%	-96.48%	-2.63%
Max Drawdown (5Y) Largest decline over 5 years	-99.64%	-99.17%	-0.47%
Max Drawdown (10Y) Largest decline over 10 years	—	-99.62%	—
Current Drawdown Current decline from peak	-99.51%	-99.58%	+0.07%
Average Drawdown Average peak-to-trough decline	-69.57%	-84.04%	+14.47%
Ulcer Index Depth and duration of drawdowns from previous peaks	63.00%	42.24%	+20.76%

Volatility

OM vs. SGMO - Volatility Comparison

The current volatility for Outset Medical, Inc. (OM) is 34.69%, while Sangamo Therapeutics, Inc. (SGMO) has a volatility of 44.87%. This indicates that OM experiences smaller price fluctuations and is considered to be less risky than SGMO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	OM	SGMO	Difference
Volatility (1M) Calculated over the trailing 1-month period	34.69%	44.87%	-10.18%
Volatility (6M) Calculated over the trailing 6-month period	63.81%	116.25%	-52.44%
Volatility (1Y) Calculated over the trailing 1-year period	95.97%	125.65%	-29.68%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	99.69%	112.76%	-13.07%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	95.52%	98.47%	-2.95%

Dividends

OM vs. SGMO - Dividend Comparison

Neither OM nor SGMO has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both OM and SGMO in my portfolio?

OM and SGMO have a correlation of 0.24, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, OM or SGMO?

SGMO has higher volatility (44.87%) compared to OM (34.69%). In terms of maximum drawdown, OM dropped -99.67% vs SGMO's -99.80%.

Which has better risk-adjusted returns?

SGMO currently has the higher Sharpe Ratio (-0.46 vs -0.79), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.