OM vs. SGMO

Last updated Apr 2, 2026

Compare and contrast key facts about Outset Medical, Inc. (OM) and Sangamo Therapeutics, Inc. (SGMO).

Performance

OM vs. SGMO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Outset Medical, Inc. (OM) and Sangamo Therapeutics, Inc. (SGMO). The values are adjusted to include any dividend payments, if applicable.

OM vs. SGMO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020
OM Outset Medical, Inc.	3.50%	-77.72%	-79.48%	-79.05%	-43.98%	-18.91%	-6.33%
SGMO Sangamo Therapeutics, Inc.	-38.07%	-58.82%	87.74%	-82.70%	-58.13%	-51.94%	46.25%

Fundamentals

Market Cap OM : $68.42M SGMO : $87.84M
EPS OM : -$4.59 SGMO : -$0.41
PS Ratio OM : 0.57 SGMO : 1.97
Total Revenue (TTM) OM : $119.48M SGMO : $39.55M
Gross Profit (TTM) OM : $46.75M SGMO : $25.32M
EBITDA (TTM) OM : -$67.79M SGMO : -$117.16M

Returns By Period

In the year-to-date period, OM achieves a 3.50% return, which is significantly higher than SGMO's -38.07% return.

OM

• 1D: 0.00%
• 1M: 7.56%
• YTD: 3.50%
• 6M: -72.61%
• 1Y: -64.80%
• 3Y*: -75.95%
• 5Y*: -65.96%
• 10Y*: —

SGMO

• 1D: 5.35%
• 1M: -39.50%
• YTD: -38.07%
• 6M: -61.44%
• 1Y: -54.38%
• 3Y*: -47.13%
• 5Y*: -53.74%
• 10Y*: -27.19%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

OM vs. SGMO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

OM

OM Risk / Return Rank: 15
OM Sharpe Ratio Rank: 13
OM Sortino Ratio Rank: 17
OM Omega Ratio Rank: 16
OM Calmar Ratio Rank: 13
OM Martin Ratio Rank: 17

SGMO

SGMO Risk / Return Rank: 16
SGMO Sharpe Ratio Rank: 18
SGMO Sortino Ratio Rank: 23
SGMO Omega Ratio Rank: 23
SGMO Calmar Ratio Rank: 9
SGMO Martin Ratio Rank: 8

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

OM vs. SGMO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Outset Medical, Inc. (OM) and Sangamo Therapeutics, Inc. (SGMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	OM	SGMO	Difference
Sharpe ratio Return per unit of total volatility	-0.63	-0.51	-0.13
Sortino ratio Return per unit of downside risk	-0.62	-0.26	-0.37
Omega ratio Gain probability vs. loss probability	0.91	0.97	-0.05
Calmar ratio Return relative to maximum drawdown	-0.77	-0.87	+0.10
Martin ratio Return relative to average drawdown	-1.22	-1.54	+0.32
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

OM vs. SGMO - Sharpe Ratio Comparison

The current OM Sharpe Ratio is -0.63, which is comparable to the SGMO Sharpe Ratio of -0.51. The chart below compares the historical Sharpe Ratios of OM and SGMO, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	OM	SGMO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	-0.63	-0.51	-0.13
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.67	-0.51	-0.16
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.29	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.66	-0.16	-0.49

Correlation

The correlation between OM and SGMO is 0.25, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

OM vs. SGMO - Dividend Comparison

Neither OM nor SGMO has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

OM vs. SGMO - Drawdown Comparison

The maximum OM drawdown since its inception was -99.67%, roughly equal to the maximum SGMO drawdown of -99.50%. Use the drawdown chart below to compare losses from any high point for OM and SGMO.

Drawdown Indicators

	OM	SGMO	Difference
Max Drawdown Largest peak-to-trough decline	-99.67%	-99.50%	-0.17%
Max Drawdown (1Y) Largest decline over 1 year	-85.12%	-69.70%	-15.42%
Max Drawdown (5Y) Largest decline over 5 years	-99.65%	-98.05%	-1.60%
Max Drawdown (10Y) Largest decline over 10 years	—	-99.06%	—
Current Drawdown Current decline from peak	-99.60%	-99.48%	-0.12%
Average Drawdown Average peak-to-trough decline	-68.62%	-83.93%	+15.31%
Ulcer Index Depth and duration of drawdowns from previous peaks	53.63%	39.13%	+14.50%

Volatility

OM vs. SGMO - Volatility Comparison

The current volatility for Outset Medical, Inc. (OM) is 18.14%, while Sangamo Therapeutics, Inc. (SGMO) has a volatility of 28.34%. This indicates that OM experiences smaller price fluctuations and is considered to be less risky than SGMO based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	OM	SGMO	Difference
Volatility (1M) Calculated over the trailing 1-month period	18.14%	28.34%	-10.20%
Volatility (6M) Calculated over the trailing 6-month period	91.73%	78.81%	+12.92%
Volatility (1Y) Calculated over the trailing 1-year period	102.71%	108.44%	-5.73%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	98.80%	106.51%	-7.71%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	95.80%	95.01%	+0.79%

Financials