NTRA vs. PFE
NTRA (Natera, Inc.) and PFE (Pfizer Inc.) are both stocks. Both are in the Healthcare sector — NTRA in Diagnostics & Research, PFE in Drug Manufacturers - General. Over the past 10 years, NTRA returned 35.27%/yr vs 1.41%/yr for PFE. Their 0.16 correlation means their historical movements had little consistent relationship.
Performance
NTRA vs. PFE - Performance Comparison
Loading charts...
Returns By Period
In the year-to-date period, NTRA achieves a 16.88% return, which is significantly higher than PFE's 5.63% return. Over the past 10 years, NTRA has outperformed PFE with an annualized return of 35.27%, while PFE has yielded a comparatively lower 1.41% annualized return.
NTRA
- 1D
- -0.70%
- 1M
- -4.14%
- 6M
- 15.84%
- YTD
- 16.88%
- 1Y
- 98.96%
- 3Y*
- 80.73%
- 5Y*
- 18.51%
- 10Y*
- 35.27%
- ALL TIME*
- 25.25%
PFE
- 1D
- 0.40%
- 1M
- 4.64%
- 6M
- -2.16%
- YTD
- 5.63%
- 1Y
- 13.94%
- 3Y*
- -5.21%
- 5Y*
- -5.31%
- 10Y*
- 1.41%
- ALL TIME*
- 9.09%
Liquidity Comparison
| Position | Avg. Volume Value (2W) | Avg. Volume Value (1M) | Avg. Volume Value (3M) |
|---|---|---|---|
NTRA Natera, Inc. | $246.10M | $302.11M | $352.98M |
PFE Pfizer Inc. | $911.93M | $985.34M | $1.04B |
NTRA vs. PFE - Yearly Performance Comparison
| 2026 (YTD) | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | |
|---|---|---|---|---|---|---|---|---|---|---|
NTRA Natera, Inc. | 16.88% | 44.72% | 152.71% | 55.94% | -56.99% | -6.16% | 195.40% | 141.33% | 55.28% | -23.23% |
PFE Pfizer Inc. | 5.63% | 0.65% | -2.22% | -41.26% | -10.41% | 66.70% | 3.07% | -6.91% | 24.82% | 15.90% |
Correlation
The correlation between NTRA and PFE is 0.17, which is low. Their historical price movements had little consistent relationship.
| Correlation | |
|---|---|
Correlation (1Y) Focuses on recent behavior, but can change the most. | 0.17 |
Correlation (3Y) Balances recent behavior with more history. | 0.11 |
Correlation (5Y) Shows whether the relationship held over a longer period. | 0.12 |
Correlation (10Y) Provides a long-term view across more market conditions. | 0.16 |
Correlation (All Time) Calculated using the full available price history since Jul 2, 2015 | 0.16 |
Fundamentals
NTRA:
$38.35B
PFE:
$142.54B
NTRA:
-$1.63
PFE:
$1.31
NTRA:
14.83
PFE:
2.26
NTRA:
21.36
PFE:
1.59
NTRA:
$2.50B
PFE:
$63.32B
NTRA:
$1.63B
PFE:
$43.91B
NTRA:
-$294.86M
PFE:
$16.94B
Compare stocks, funds, or ETFs
Search for stocks, ETFs, and funds for a quick comparison or use the comparison tool for more options.
Return for Risk
NTRA vs. PFE — Risk / Return Rank
NTRA
PFE
NTRA vs. PFE - Risk-Adjusted Trends Comparison
This table presents a comparison of risk-adjusted performance metrics for Natera, Inc. (NTRA) and Pfizer Inc. (PFE). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.
Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.
| NTRA | PFE | Difference | |
|---|---|---|---|
| Sharpe ratioReturn per unit of total volatility | +1.68 | ||
| Sortino ratioReturn per unit of downside risk | +1.65 | ||
| Omega ratioGain probability vs. loss probability | 1.36 | 1.13 | +0.23 |
| Calmar ratioReturn relative to maximum drawdown | 3.58 | 0.95 | +2.62 |
| Martin ratioReturn relative to average drawdown | 8.06 | 2.13 | +5.93 |
Loading charts...
Drawdowns
NTRA vs. PFE - Drawdown Comparison
The maximum NTRA drawdown since its inception was -77.74%, which is greater than PFE's maximum drawdown of -69.24%. Use the drawdown chart below to compare losses from any high point for NTRA and PFE.
Loading charts...
Drawdown Indicators
| NTRA | PFE | Difference | |
|---|---|---|---|
Max DrawdownLargest peak-to-trough decline | -77.74% | -69.24% | -8.50% |
Max Drawdown (1Y)Largest decline over 1 year | -28.20% | -15.72% | -12.48% |
Max Drawdown (3Y)Largest decline over 3 years | -39.94% | -36.23% | -3.71% |
Max Drawdown (5Y)Largest decline over 5 years | -77.74% | -58.96% | -18.78% |
Max Drawdown (10Y)Largest decline over 10 years | -77.74% | -58.96% | -18.78% |
Current DrawdownCurrent decline from peak | -5.65% | -47.26% | +41.61% |
Average DrawdownAverage peak-to-trough decline | -33.10% | -22.96% | -10.14% |
Ulcer IndexDepth and duration of drawdowns from previous peaks | 12.50% | 7.03% | +5.47% |
Volatility
NTRA vs. PFE - Volatility Comparison
Natera, Inc. (NTRA) has a higher volatility of 10.71% compared to Pfizer Inc. (PFE) at 5.62%. This indicates that NTRA's price experiences larger fluctuations and is considered to be riskier than PFE based on this measure. The chart below showcases a comparison of their rolling one-month volatility.
Loading charts...
Volatility by Period
| NTRA | PFE | Difference | |
|---|---|---|---|
Volatility (1M)Calculated over the trailing 1-month period | 10.71% | 5.62% | +5.09% |
Volatility (6M)Calculated over the trailing 6-month period | 36.89% | 15.06% | +21.83% |
Volatility (1Y)Calculated over the trailing 1-year period | 44.12% | 23.95% | +20.17% |
Volatility (5Y)Calculated over the trailing 5-year period, annualized | 57.04% | 25.60% | +31.44% |
Volatility (10Y)Calculated over the trailing 10-year period, annualized | 60.84% | 23.98% | +36.86% |
Dividends
NTRA vs. PFE - Dividend Comparison
NTRA has not paid dividends to shareholders, while PFE's dividend yield for the trailing twelve months is around 6.88%.
| Position | TTM | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 | 2019 | 2018 | 2017 | 2016 | 2015 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
NTRA Natera, Inc. | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% | 0.00% |
PFE Pfizer Inc. | 6.88% | 6.91% | 6.33% | 5.70% | 3.12% | 2.64% | 3.92% | 3.68% | 3.12% | 3.53% | 3.69% | 3.47% |
Financials
NTRA vs. PFE - Financials Comparison
This section allows you to compare key financial metrics between Natera, Inc. and Pfizer Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.
Total Revenue: Total amount of money received from sales and other business activities
NTRA vs. PFE - Profitability Comparison
NTRA - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Natera, Inc. reported a gross profit of 451.44M and revenue of 696.64M. Therefore, the gross margin over that period was 64.8%.
PFE - Gross Margin
Gross margin is calculated as gross profit divided by revenue. For the three months ending on Aug 2026, Pfizer Inc. reported a gross profit of 9.72B and revenue of 14.45B. Therefore, the gross margin over that period was 67.3%.
NTRA - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Natera, Inc. reported an operating income of -93.52M and revenue of 696.64M, resulting in an operating margin of -13.4%.
PFE - Operating Margin
Operating margin is calculated as operating income divided by revenue. For the three months ending on Aug 2026, Pfizer Inc. reported an operating income of 4.03B and revenue of 14.45B, resulting in an operating margin of 27.9%.
NTRA - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Natera, Inc. reported a net income of -85.09M and revenue of 696.64M, resulting in a net margin of -12.2%.
PFE - Net Margin
Net margin is calculated as net income divided by revenue. For the three months ending on Aug 2026, Pfizer Inc. reported a net income of 2.69B and revenue of 14.45B, resulting in a net margin of 18.6%.
Frequently Asked Questions
NTRA and PFE have a correlation of 0.17, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.
NTRA has higher volatility (10.71%) compared to PFE (5.62%). In terms of maximum drawdown, NTRA dropped -77.74% vs PFE's -69.24%.
NTRA currently has the higher Sharpe Ratio (2.30 vs 0.63), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.
Find the right allocation for NTRA and PFE
Add both to a portfolio and optimize allocations for your target — whether that's maximizing returns, minimizing drawdowns, or balancing risk across holdings.
Open Portfolio Optimizer