NDRA vs. JAGX

Last updated Apr 2, 2026

Compare and contrast key facts about ENDRA Life Sciences Inc. (NDRA) and Jaguar Health, Inc. (JAGX).

Performance

NDRA vs. JAGX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ENDRA Life Sciences Inc. (NDRA) and Jaguar Health, Inc. (JAGX). The values are adjusted to include any dividend payments, if applicable.

NDRA vs. JAGX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
NDRA ENDRA Life Sciences Inc.	2.65%	-27.64%	-99.83%	-47.91%	-70.58%	-7.76%	-55.36%	12.00%	-69.14%	24.62%
JAGX Jaguar Health, Inc.	-47.24%	-96.31%	-88.88%	-97.68%	-91.64%	-57.46%	1.75%	-95.00%	-89.10%	-73.56%

Fundamentals

Market Cap NDRA : $3.66M JAGX : $614.35K
EPS NDRA : -$9.31 JAGX : -$31.88
PB Ratio NDRA : 1.62 JAGX : 0.20
Total Revenue (TTM) NDRA : $0.00 JAGX : $11.79M
Gross Profit (TTM) NDRA : -$117.76K JAGX : $9.09M
EBITDA (TTM) NDRA : -$3.74M JAGX : -$41.16M

Returns By Period

In the year-to-date period, NDRA achieves a 2.65% return, which is significantly higher than JAGX's -47.24% return.

NDRA

• 1D: 0.00%
• 1M: 18.62%
• YTD: 2.65%
• 6M: -17.23%
• 1Y: 18.62%
• 3Y*: -89.49%
• 5Y*: -86.29%
• 10Y*: —

JAGX

• 1D: 9.58%
• 1M: -49.31%
• YTD: -47.24%
• 6M: -77.97%
• 1Y: -89.68%
• 3Y*: -91.95%
• 5Y*: -94.07%
• 10Y*: -87.57%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

NDRA vs. JAGX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NDRA

NDRA Risk / Return Rank: 55
NDRA Sharpe Ratio Rank: 44
NDRA Sortino Ratio Rank: 72
NDRA Omega Ratio Rank: 72
NDRA Calmar Ratio Rank: 45
NDRA Martin Ratio Rank: 44

JAGX

JAGX Risk / Return Rank: 11
JAGX Sharpe Ratio Rank: 15
JAGX Sortino Ratio Rank: 7
JAGX Omega Ratio Rank: 9
JAGX Calmar Ratio Rank: 6
JAGX Martin Ratio Rank: 20

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NDRA vs. JAGX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ENDRA Life Sciences Inc. (NDRA) and Jaguar Health, Inc. (JAGX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	NDRA	JAGX	Difference
Sharpe ratio Return per unit of total volatility	0.10	-0.59	+0.69
Sortino ratio Return per unit of downside risk	1.75	-1.28	+3.03
Omega ratio Gain probability vs. loss probability	1.24	0.85	+0.39
Calmar ratio Return relative to maximum drawdown	0.21	-0.93	+1.14
Martin ratio Return relative to average drawdown	0.30	-1.11	+1.41
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

NDRA vs. JAGX - Sharpe Ratio Comparison

The current NDRA Sharpe Ratio is 0.10, which is higher than the JAGX Sharpe Ratio of -0.59. The chart below compares the historical Sharpe Ratios of NDRA and JAGX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	NDRA	JAGX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.10	-0.59	+0.69
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	-0.61	-0.70	+0.09
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.51	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.53	-0.52	-0.02

Correlation

The correlation between NDRA and JAGX is 0.13, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

NDRA vs. JAGX - Dividend Comparison

Neither NDRA nor JAGX has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

NDRA vs. JAGX - Drawdown Comparison

The maximum NDRA drawdown since its inception was -100.00%, roughly equal to the maximum JAGX drawdown of -100.00%. Use the drawdown chart below to compare losses from any high point for NDRA and JAGX.

Drawdown Indicators

	NDRA	JAGX	Difference
Max Drawdown Largest peak-to-trough decline	-100.00%	-100.00%	0.00%
Max Drawdown (1Y) Largest decline over 1 year	-63.12%	-96.90%	+33.78%
Max Drawdown (5Y) Largest decline over 5 years	-100.00%	-100.00%	0.00%
Max Drawdown (10Y) Largest decline over 10 years	—	-100.00%	—
Current Drawdown Current decline from peak	-100.00%	-100.00%	0.00%
Average Drawdown Average peak-to-trough decline	-78.76%	-93.99%	+15.23%
Ulcer Index Depth and duration of drawdowns from previous peaks	44.80%	81.05%	-36.25%

Volatility

NDRA vs. JAGX - Volatility Comparison

The current volatility for ENDRA Life Sciences Inc. (NDRA) is 28.44%, while Jaguar Health, Inc. (JAGX) has a volatility of 38.27%. This indicates that NDRA experiences smaller price fluctuations and is considered to be less risky than JAGX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	NDRA	JAGX	Difference
Volatility (1M) Calculated over the trailing 1-month period	28.44%	38.27%	-9.83%
Volatility (6M) Calculated over the trailing 6-month period	77.12%	116.91%	-39.79%
Volatility (1Y) Calculated over the trailing 1-year period	188.34%	151.66%	+36.68%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	142.77%	135.45%	+7.32%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	129.63%	172.03%	-42.40%

Financials