NDRA vs. JAGX

Last updated Jul 14, 2026

NDRA (ENDRA Life Sciences Inc.) and JAGX (Jaguar Health, Inc.) are both stocks. Both are in the Healthcare sector — NDRA in Diagnostics & Research, JAGX in Biotechnology. Over the past 5 years, NDRA returned -66.56%/yr vs -95.56%/yr for JAGX. At a 0.14 correlation, their price movements are largely independent.

Performance

NDRA vs. JAGX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in ENDRA Life Sciences Inc. (NDRA) and Jaguar Health, Inc. (JAGX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, NDRA achieves a 21.41% return, which is significantly higher than JAGX's -91.65% return.

NDRA

• 1D: -1.96%
• 1M: 20.61%
• 6M: 21.95%
• YTD: 21.41%
• 1Y: -32.10%
• 3Y*: -51.29%
• 5Y*: -66.56%
• 10Y*: —

JAGX

• 1D: -2.60%
• 1M: -16.36%
• 6M: -90.63%
• YTD: -91.65%
• 1Y: -97.12%
• 3Y*: -95.44%
• 5Y*: -95.56%
• 10Y*: -89.88%

*Multi-year figures are annualized to reflect compound growth (CAGR)

NDRA vs. JAGX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
NDRA ENDRA Life Sciences Inc.	21.41%	-27.64%	-91.56%	-47.91%	-70.58%	-7.76%	-55.36%	12.00%	-69.14%	21.96%
JAGX Jaguar Health, Inc.	-91.65%	-96.31%	-88.88%	-97.68%	-91.64%	-57.46%	1.75%	-95.00%	-89.10%	-74.55%

Correlation

The correlation between NDRA and JAGX is 0.14, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.14
Correlation (3Y) Calculated over the trailing 3-year period	0.06
Correlation (5Y) Calculated over the trailing 5-year period	0.13
Correlation (All Time) Calculated using the full available price history since Jun 30, 2017	0.14

Fundamentals

Market Cap NDRA : $4.14M JAGX : $149.94K
EPS NDRA : -$9.08 JAGX : -$27.86
Total Revenue (TTM) NDRA : $0.00 JAGX : $11.51M
Gross Profit (TTM) NDRA : -$117.76K JAGX : $7.74M
EBITDA (TTM) NDRA : -$3.74M JAGX : -$45.91M

Return for Risk

NDRA vs. JAGX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

NDRA

NDRA Risk / Return Rank: 33
NDRA Sharpe Ratio Rank: 32
NDRA Sortino Ratio Rank: 40
NDRA Omega Ratio Rank: 40
NDRA Calmar Ratio Rank: 25
NDRA Martin Ratio Rank: 29

JAGX

JAGX Risk / Return Rank: 6
JAGX Sharpe Ratio Rank: 16
JAGX Sortino Ratio Rank: 2
JAGX Omega Ratio Rank: 3
JAGX Calmar Ratio Rank: 0
JAGX Martin Ratio Rank: 6

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

NDRA vs. JAGX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for ENDRA Life Sciences Inc. (NDRA) and Jaguar Health, Inc. (JAGX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	NDRA	JAGX	Difference
Sharpe ratio: Return per unit of total volatility	-0.30	-0.63	+0.33
Sortino ratio: Return per unit of downside risk	0.26	-2.19	+2.46
Omega ratio: Gain probability vs. loss probability	1.03	0.72	+0.31
Calmar ratio: Return relative to maximum drawdown	-0.54	-1.00	+0.46
Martin ratio: Return relative to average drawdown	-0.80	-1.50	+0.70

NDRA vs. JAGX - Sharpe Ratio Comparison

The current NDRA Sharpe Ratio is -0.30, which is higher than the JAGX Sharpe Ratio of -0.63. The chart below compares the historical Sharpe Ratios of NDRA and JAGX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

NDRA vs. JAGX - Drawdown Comparison

The maximum NDRA drawdown since its inception was -99.97%, roughly equal to the maximum JAGX drawdown of -100.00%. Use the drawdown chart below to compare losses from any high point for NDRA and JAGX.

Drawdown Indicators

	NDRA	JAGX	Difference
Max Drawdown Largest peak-to-trough decline	-99.97%	-100.00%	+0.03%
Max Drawdown (1Y) Largest decline over 1 year	-59.85%	-97.00%	+37.15%
Max Drawdown (3Y) Largest decline over 3 years	-98.70%	-99.99%	+1.29%
Max Drawdown (5Y) Largest decline over 5 years	-99.92%	-100.00%	+0.08%
Max Drawdown (10Y) Largest decline over 10 years	—	-100.00%	—
Current Drawdown Current decline from peak	-99.85%	-100.00%	+0.15%
Average Drawdown Average peak-to-trough decline	-79.42%	-94.10%	+14.68%
Ulcer Index Depth and duration of drawdowns from previous peaks	40.27%	65.72%	-25.45%

Volatility

NDRA vs. JAGX - Volatility Comparison

ENDRA Life Sciences Inc. (NDRA) has a higher volatility of 51.01% compared to Jaguar Health, Inc. (JAGX) at 27.51%. This indicates that NDRA's price experiences larger fluctuations and is considered to be riskier than JAGX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	NDRA	JAGX	Difference
Volatility (1M) Calculated over the trailing 1-month period	51.01%	27.51%	+23.50%
Volatility (6M) Calculated over the trailing 6-month period	78.76%	140.61%	-61.85%
Volatility (1Y) Calculated over the trailing 1-year period	107.66%	154.70%	-47.04%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	874.59%	137.94%	+736.65%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	654.04%	171.78%	+482.26%

Dividends

NDRA vs. JAGX - Dividend Comparison

Neither NDRA nor JAGX has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both NDRA and JAGX in my portfolio?

NDRA and JAGX have a correlation of 0.14, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, NDRA or JAGX?

NDRA has higher volatility (51.01%) compared to JAGX (27.51%). In terms of maximum drawdown, NDRA dropped -99.97% vs JAGX's -100.00%.

Which has better risk-adjusted returns?

NDRA currently has the higher Sharpe Ratio (-0.30 vs -0.63), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.