MXDPX vs. SHSAX

Last updated Jun 23, 2026

MXDPX (Great-West Moderately Conservative Profile Fund) and SHSAX (BlackRock Health Sciences Opportunities Portfolio) are both mutual funds - MXDPX is a Diversified Portfolio fund managed by Great-West, while SHSAX is a Health & Biotech Equities fund managed by BlackRock. Over the past 10 years, MXDPX returned 5.38%/yr vs 9.67%/yr for SHSAX. A 0.66 correlation means they provide meaningful diversification when combined. MXDPX charges 0.37%/yr vs 1.09%/yr for SHSAX.

Performance

MXDPX vs. SHSAX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Great-West Moderately Conservative Profile Fund (MXDPX) and BlackRock Health Sciences Opportunities Portfolio (SHSAX). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, MXDPX achieves a 5.73% return, which is significantly higher than SHSAX's -2.94% return. Over the past 10 years, MXDPX has underperformed SHSAX with an annualized return of 5.38%, while SHSAX has yielded a comparatively higher 9.67% annualized return.

MXDPX

• 1D: 0.34%
• 1M: 1.14%
• YTD: 5.73%
• 6M: 5.49%
• 1Y: 12.40%
• 3Y*: 9.03%
• 5Y*: 4.51%
• 10Y*: 5.38%

SHSAX

• 1D: -0.65%
• 1M: 0.38%
• YTD: -2.94%
• 6M: -3.69%
• 1Y: 16.32%
• 3Y*: 6.12%
• 5Y*: 3.78%
• 10Y*: 9.67%

*Multi-year figures are annualized to reflect compound growth (CAGR)

MXDPX vs. SHSAX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
MXDPX Great-West Moderately Conservative Profile Fund	5.73%	10.02%	6.17%	10.19%	-11.44%	9.24%	9.30%	14.91%	-5.19%	8.25%
SHSAX BlackRock Health Sciences Opportunities Portfolio	-2.94%	15.85%	3.73%	3.59%	-5.94%	11.88%	19.44%	25.27%	7.93%	24.74%

Correlation

The correlation between MXDPX and SHSAX is 0.53, which is moderate. They share some common price drivers but move independently often enough to provide real diversification benefit when combined.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.53
Correlation (3Y) Calculated over the trailing 3-year period	0.56
Correlation (5Y) Calculated over the trailing 5-year period	0.59
Correlation (10Y) Calculated over the trailing 10-year period	0.56
Correlation (All Time) Calculated using the full available price history since Jan 3, 2000	0.66

The correlation between MXDPX and SHSAX shifts across timeframes, from 0.53 (1 year) to 0.66 (all time), reflecting how their relationship changes across market environments.

Return for Risk

MXDPX vs. SHSAX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MXDPX

MXDPX Risk / Return Rank: 44
MXDPX Sharpe Ratio Rank: 39
MXDPX Sortino Ratio Rank: 40
MXDPX Omega Ratio Rank: 47
MXDPX Calmar Ratio Rank: 46
MXDPX Martin Ratio Rank: 46

SHSAX

SHSAX Risk / Return Rank: 18
SHSAX Sharpe Ratio Rank: 18
SHSAX Sortino Ratio Rank: 20
SHSAX Omega Ratio Rank: 17
SHSAX Calmar Ratio Rank: 22
SHSAX Martin Ratio Rank: 15

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MXDPX vs. SHSAX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Great-West Moderately Conservative Profile Fund (MXDPX) and BlackRock Health Sciences Opportunities Portfolio (SHSAX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	MXDPX	SHSAX	Difference
Sharpe ratio: Return per unit of total volatility	1.68	1.13	+0.55
Sortino ratio: Return per unit of downside risk	2.44	1.76	+0.69
Omega ratio: Gain probability vs. loss probability	1.35	1.20	+0.15
Calmar ratio: Return relative to maximum drawdown	2.49	1.62	+0.87
Martin ratio: Return relative to average drawdown	9.11	3.91	+5.20

MXDPX vs. SHSAX - Sharpe Ratio Comparison

The current MXDPX Sharpe Ratio is 1.68, which is higher than the SHSAX Sharpe Ratio of 1.13. The chart below compares the historical Sharpe Ratios of MXDPX and SHSAX, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

MXDPX vs. SHSAX - Drawdown Comparison

The maximum MXDPX drawdown since its inception was -39.33%, which is greater than SHSAX's maximum drawdown of -35.49%. Use the drawdown chart below to compare losses from any high point for MXDPX and SHSAX.

Drawdown Indicators

	MXDPX	SHSAX	Difference
Max Drawdown Largest peak-to-trough decline	-39.33%	-35.49%	-3.84%
Max Drawdown (1Y) Largest decline over 1 year	-4.94%	-9.87%	+4.93%
Max Drawdown (3Y) Largest decline over 3 years	-7.03%	-16.08%	+9.05%
Max Drawdown (5Y) Largest decline over 5 years	-20.55%	-17.99%	-2.56%
Max Drawdown (10Y) Largest decline over 10 years	-20.55%	-28.36%	+7.81%
Current Drawdown Current decline from peak	-0.34%	-5.73%	+5.39%
Average Drawdown Average peak-to-trough decline	-13.91%	-6.17%	-7.74%
Ulcer Index Depth and duration of drawdowns from previous peaks	1.35%	4.08%	-2.73%

Volatility

MXDPX vs. SHSAX - Volatility Comparison

The current volatility for Great-West Moderately Conservative Profile Fund (MXDPX) is 2.39%, while BlackRock Health Sciences Opportunities Portfolio (SHSAX) has a volatility of 4.95%. This indicates that MXDPX experiences smaller price fluctuations and is considered to be less risky than SHSAX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MXDPX	SHSAX	Difference
Volatility (1M) Calculated over the trailing 1-month period	2.39%	4.95%	-2.56%
Volatility (6M) Calculated over the trailing 6-month period	5.09%	10.65%	-5.56%
Volatility (1Y) Calculated over the trailing 1-year period	7.32%	14.14%	-6.82%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	9.09%	14.44%	-5.35%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	8.91%	16.56%	-7.65%

MXDPX vs. SHSAX - Expense Ratio Comparison

MXDPX has a 0.37% expense ratio, which is lower than SHSAX's 1.09% expense ratio.

Dividends

MXDPX vs. SHSAX - Dividend Comparison

MXDPX's dividend yield for the trailing twelve months is around 4.99%, less than SHSAX's 10.96% yield.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
MXDPX Great-West Moderately Conservative Profile Fund	4.99%	5.27%	4.86%	5.29%	6.69%	6.84%	2.38%	7.36%	7.84%	2.90%	0.00%	0.00%
SHSAX BlackRock Health Sciences Opportunities Portfolio	10.96%	10.63%	9.18%	3.84%	7.44%	9.20%	4.34%	3.89%	8.56%	3.53%	2.43%	12.58%

Frequently Asked Questions

Can I hold both MXDPX and SHSAX in my portfolio?

MXDPX and SHSAX have a correlation of 0.53, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, MXDPX or SHSAX?

SHSAX has higher volatility (4.95%) compared to MXDPX (2.39%). In terms of maximum drawdown, MXDPX dropped -39.33% vs SHSAX's -35.49%.

Which has better risk-adjusted returns?

MXDPX currently has the higher Sharpe Ratio (1.68 vs 1.13), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.