MSFRX vs. PDSB

Last updated Jun 23, 2026

MSFRX (MFS Total Return Fund) is Diversified Portfolio fund managed by MFS, while PDSB (PDS Biotechnology Corporation) is a stock. Over the past 10 years, MSFRX returned 7.95%/yr vs -40.99%/yr for PDSB. At a 0.26 correlation, their price movements are largely independent.

Performance

MSFRX vs. PDSB - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in MFS Total Return Fund (MSFRX) and PDS Biotechnology Corporation (PDSB). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

In the year-to-date period, MSFRX achieves a 2.50% return, which is significantly lower than PDSB's 22.27% return. Over the past 10 years, MSFRX has outperformed PDSB with an annualized return of 7.95%, while PDSB has yielded a comparatively lower -40.99% annualized return.

MSFRX

• 1D: -0.46%
• 1M: -0.25%
• YTD: 2.50%
• 6M: 2.31%
• 1Y: 10.56%
• 3Y*: 11.48%
• 5Y*: 6.68%
• 10Y*: 7.95%

PDSB

• 1D: -1.45%
• 1M: -21.57%
• YTD: 22.27%
• 6M: 4.68%
• 1Y: -41.90%
• 3Y*: -44.31%
• 5Y*: -38.82%
• 10Y*: -40.99%

*Multi-year figures are annualized to reflect compound growth (CAGR)

MSFRX vs. PDSB - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
MSFRX MFS Total Return Fund	2.50%	10.98%	14.73%	10.34%	-9.70%	14.00%	9.72%	20.20%	-5.80%	12.18%
PDSB PDS Biotechnology Corporation	22.27%	-52.77%	-67.20%	-62.35%	62.96%	278.50%	-19.25%	-58.72%	-96.57%	-25.04%

Correlation

The correlation between MSFRX and PDSB is 0.22, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.22
Correlation (3Y) Calculated over the trailing 3-year period	0.29
Correlation (5Y) Calculated over the trailing 5-year period	0.33
Correlation (10Y) Calculated over the trailing 10-year period	0.25
Correlation (All Time) Calculated using the full available price history since Oct 1, 2015	0.26

The correlation between MSFRX and PDSB shifts across timeframes, from 0.22 (1 year) to 0.33 (5 years), reflecting how their relationship changes across market environments.

Return for Risk

MSFRX vs. PDSB — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MSFRX

MSFRX Risk / Return Rank: 33
MSFRX Sharpe Ratio Rank: 33
MSFRX Sortino Ratio Rank: 37
MSFRX Omega Ratio Rank: 32
MSFRX Calmar Ratio Rank: 36
MSFRX Martin Ratio Rank: 29

PDSB

PDSB Risk / Return Rank: 24
PDSB Sharpe Ratio Rank: 23
PDSB Sortino Ratio Rank: 29
PDSB Omega Ratio Rank: 30
PDSB Calmar Ratio Rank: 18
PDSB Martin Ratio Rank: 20

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MSFRX vs. PDSB - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for MFS Total Return Fund (MSFRX) and PDS Biotechnology Corporation (PDSB). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.

	MSFRX	PDSB	Difference
Sharpe ratio: Return per unit of total volatility	1.55	-0.42	+1.97
Sortino ratio: Return per unit of downside risk	2.34	-0.08	+2.42
Omega ratio: Gain probability vs. loss probability	1.28	0.99	+0.29
Calmar ratio: Return relative to maximum drawdown	2.15	-0.63	+2.78
Martin ratio: Return relative to average drawdown	6.26	-1.04	+7.30

MSFRX vs. PDSB - Sharpe Ratio Comparison

The current MSFRX Sharpe Ratio is 1.55, which is higher than the PDSB Sharpe Ratio of -0.42. The chart below compares the historical Sharpe Ratios of MSFRX and PDSB, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.

Drawdowns

MSFRX vs. PDSB - Drawdown Comparison

The maximum MSFRX drawdown since its inception was -37.28%, smaller than the maximum PDSB drawdown of -99.89%. Use the drawdown chart below to compare losses from any high point for MSFRX and PDSB.

Drawdown Indicators

	MSFRX	PDSB	Difference
Max Drawdown Largest peak-to-trough decline	-37.28%	-99.89%	+62.61%
Max Drawdown (1Y) Largest decline over 1 year	-4.96%	-66.47%	+61.51%
Max Drawdown (3Y) Largest decline over 3 years	-8.56%	-91.86%	+83.30%
Max Drawdown (5Y) Largest decline over 5 years	-17.02%	-96.86%	+79.84%
Max Drawdown (10Y) Largest decline over 10 years	-24.70%	-99.85%	+75.15%
Current Drawdown Current decline from peak	-2.61%	-99.80%	+97.19%
Average Drawdown Average peak-to-trough decline	-5.00%	-88.20%	+83.20%
Ulcer Index Depth and duration of drawdowns from previous peaks	1.70%	41.08%	-39.38%

Volatility

MSFRX vs. PDSB - Volatility Comparison

The current volatility for MFS Total Return Fund (MSFRX) is 2.09%, while PDS Biotechnology Corporation (PDSB) has a volatility of 32.19%. This indicates that MSFRX experiences smaller price fluctuations and is considered to be less risky than PDSB based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MSFRX	PDSB	Difference
Volatility (1M) Calculated over the trailing 1-month period	2.09%	32.19%	-30.10%
Volatility (6M) Calculated over the trailing 6-month period	5.04%	84.86%	-79.82%
Volatility (1Y) Calculated over the trailing 1-year period	6.88%	99.79%	-92.91%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	9.76%	89.33%	-79.57%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	10.46%	101.49%	-91.03%

Dividends

MSFRX vs. PDSB - Dividend Comparison

MSFRX's dividend yield for the trailing twelve months is around 8.84%, while PDSB has not paid dividends to shareholders.

Position	TTM	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015
MSFRX MFS Total Return Fund	8.84%	8.93%	14.87%	6.19%	5.38%	8.33%	6.93%	3.22%	4.99%	5.67%	3.54%	5.55%
PDSB PDS Biotechnology Corporation	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%	0.00%

Frequently Asked Questions

Can I hold both MSFRX and PDSB in my portfolio?

MSFRX and PDSB have a correlation of 0.22, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

Which is riskier, MSFRX or PDSB?

PDSB has higher volatility (32.19%) compared to MSFRX (2.09%). In terms of maximum drawdown, MSFRX dropped -37.28% vs PDSB's -99.89%.

Which has better risk-adjusted returns?

MSFRX currently has the higher Sharpe Ratio (1.55 vs -0.42), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.