MRSN vs. SGMO

Last updated Jun 5, 2026

MRSN (Mersana Therapeutics, Inc.) and SGMO (Sangamo Therapeutics, Inc.) are both stocks. Both operate in the Biotechnology industry within the Healthcare sector. At a 0.35 correlation, their price movements are largely independent.

Performance

MRSN vs. SGMO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Mersana Therapeutics, Inc. (MRSN) and Sangamo Therapeutics, Inc. (SGMO). The values are adjusted to include any dividend payments, if applicable.

Returns By Period

MRSN

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

SGMO

• 1D: -2.57%
• 1M: 89.08%
• YTD: -49.85%
• 6M: -60.26%
• 1Y: -57.19%
• 3Y*: -43.37%
• 5Y*: -54.57%
• 10Y*: -30.04%

*Multi-year figures are annualized to reflect compound growth (CAGR)

MRSN vs. SGMO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019	2018	2017
MRSN Mersana Therapeutics, Inc.	0.52%	-19.08%	-38.36%	-60.41%	-5.79%	-76.63%	364.40%	40.44%	-75.17%	17.36%
SGMO Sangamo Therapeutics, Inc.	-49.85%	-58.82%	87.74%	-82.70%	-58.13%	-51.94%	86.44%	-27.09%	-30.00%	81.22%

Correlation

The correlation between MRSN and SGMO is 0.11, which is low. Their price movements are largely independent, making them effective diversification partners.

	Correlation
Correlation (1Y) Calculated over the trailing 1-year period	0.11
Correlation (3Y) Calculated over the trailing 3-year period	0.25
Correlation (5Y) Calculated over the trailing 5-year period	0.37
Correlation (All Time) Calculated using the full available price history since Jun 29, 2017	0.35

Over the past year, the correlation between MRSN and SGMO has dropped to 0.11 - well below their long-term average of 0.35, suggesting their price drivers have been diverging.

Fundamentals

Market Cap MRSN : $145.02M SGMO : $82.07M
EPS MRSN : -$14.05 SGMO : -$0.38
PS Ratio MRSN : 4.37 SGMO : 1.96
Total Revenue (TTM) MRSN : $33.18M SGMO : $34.56M
Gross Profit (TTM) MRSN : $32.89M SGMO : $25.51M
EBITDA (TTM) MRSN : -$66.25M SGMO : -$106.29M

Return for Risk

MRSN vs. SGMO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SGMO

SGMO Risk / Return Rank: 22
SGMO Sharpe Ratio Rank: 21
SGMO Sortino Ratio Rank: 30
SGMO Omega Ratio Rank: 30
SGMO Calmar Ratio Rank: 17
SGMO Martin Ratio Rank: 10

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MRSN vs. SGMO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Mersana Therapeutics, Inc. (MRSN) and Sangamo Therapeutics, Inc. (SGMO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	MRSN	SGMO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	-0.46	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	-0.49	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.31	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	-0.17	—

Drawdowns

Drawdown Indicators

	MRSN	SGMO	Difference
Max Drawdown Largest peak-to-trough decline	—	-99.80%	—
Max Drawdown (1Y) Largest decline over 1 year	—	-86.32%	—
Max Drawdown (3Y) Largest decline over 3 years	—	-96.48%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-99.17%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-99.62%	—
Current Drawdown Current decline from peak	—	-99.58%	—
Average Drawdown Average peak-to-trough decline	—	-84.04%	—
Ulcer Index Depth and duration of drawdowns from previous peaks	—	42.24%	—

Volatility

Volatility by Period

	MRSN	SGMO	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	44.87%	—
Volatility (6M) Calculated over the trailing 6-month period	—	116.25%	—
Volatility (1Y) Calculated over the trailing 1-year period	—	125.65%	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	—	112.76%	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	—	98.47%	—

Dividends

MRSN vs. SGMO - Dividend Comparison

Neither MRSN nor SGMO has paid dividends to shareholders.

Tickers have no history of dividend payments

Financials

Frequently Asked Questions

Can I hold both MRSN and SGMO in my portfolio?

MRSN and SGMO have a correlation of 0.11, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.