MNPR vs. CALX

Last updated Apr 1, 2026

Compare and contrast key facts about Monopar Therapeutics Inc. (MNPR) and Calix, Inc. (CALX).

Performance

MNPR vs. CALX - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Monopar Therapeutics Inc. (MNPR) and Calix, Inc. (CALX). The values are adjusted to include any dividend payments, if applicable.

MNPR vs. CALX - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021	2020	2019
MNPR Monopar Therapeutics Inc.	-16.09%	196.82%	1,193.36%	-85.65%	-26.17%	-47.55%	-63.13%	-37.36%
CALX Calix, Inc.	-7.44%	51.79%	-20.19%	-36.15%	-14.43%	168.72%	272.00%	0.25%

Fundamentals

EPS MNPR : -$2.75 CALX : $0.27
Total Revenue (TTM) MNPR : $0.00 CALX : $1.00B
Gross Profit (TTM) MNPR : $0.00 CALX : $568.32M
EBITDA (TTM) MNPR : -$20.04M CALX : $37.23M

Returns By Period

In the year-to-date period, MNPR achieves a -16.09% return, which is significantly lower than CALX's -7.44% return.

MNPR

• 1D: 2.81%
• 1M: -0.03%
• YTD: -16.09%
• 6M: -32.91%
• 1Y: 50.48%
• 3Y*: 99.02%
• 5Y*: 11.99%
• 10Y*: —

CALX

• 1D: -0.83%
• 1M: -5.37%
• YTD: -7.44%
• 6M: -20.17%
• 1Y: 38.23%
• 3Y*: -2.95%
• 5Y*: 5.82%
• 10Y*: 21.27%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

MNPR vs. CALX — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MNPR

MNPR Risk / Return Rank: 61
MNPR Sharpe Ratio Rank: 63
MNPR Sortino Ratio Rank: 67
MNPR Omega Ratio Rank: 62
MNPR Calmar Ratio Rank: 59
MNPR Martin Ratio Rank: 56

CALX

CALX Risk / Return Rank: 69
CALX Sharpe Ratio Rank: 74
CALX Sortino Ratio Rank: 70
CALX Omega Ratio Rank: 68
CALX Calmar Ratio Rank: 66
CALX Martin Ratio Rank: 67

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MNPR vs. CALX - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Monopar Therapeutics Inc. (MNPR) and Calix, Inc. (CALX). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

	MNPR	CALX	Difference
Sharpe ratio Return per unit of total volatility	0.59	0.97	-0.38
Sortino ratio Return per unit of downside risk	1.44	1.58	-0.14
Omega ratio Gain probability vs. loss probability	1.17	1.21	-0.04
Calmar ratio Return relative to maximum drawdown	0.73	1.15	-0.42
Martin ratio Return relative to average drawdown	1.36	2.85	-1.49
Data is calculated on a 1-year rolling basis and updated daily. The trend shows the change in the indicator over the past month.

MNPR vs. CALX - Sharpe Ratio Comparison

The current MNPR Sharpe Ratio is 0.59, which is lower than the CALX Sharpe Ratio of 0.97. The chart below compares the historical Sharpe Ratios of MNPR and CALX, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.

Sharpe Ratios by Period

	MNPR	CALX	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	0.59	0.97	-0.38
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	0.04	0.12	-0.08
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	0.42	—
Sharpe Ratio (All Time) Calculated using the full available price history	-0.05	0.14	-0.19

Correlation

The correlation between MNPR and CALX is 0.12, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

MNPR vs. CALX - Dividend Comparison

Neither MNPR nor CALX has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

MNPR vs. CALX - Drawdown Comparison

The maximum MNPR drawdown since its inception was -98.93%, which is greater than CALX's maximum drawdown of -80.95%. Use the drawdown chart below to compare losses from any high point for MNPR and CALX.

Drawdown Indicators

	MNPR	CALX	Difference
Max Drawdown Largest peak-to-trough decline	-98.93%	-80.95%	-17.98%
Max Drawdown (1Y) Largest decline over 1 year	-49.16%	-34.71%	-14.45%
Max Drawdown (5Y) Largest decline over 5 years	-95.54%	-65.32%	-30.22%
Max Drawdown (10Y) Largest decline over 10 years	—	-65.32%	—
Current Drawdown Current decline from peak	-59.41%	-38.74%	-20.67%
Average Drawdown Average peak-to-trough decline	-81.06%	-49.00%	-32.06%
Ulcer Index Depth and duration of drawdowns from previous peaks	26.40%	13.98%	+12.42%

Volatility

MNPR vs. CALX - Volatility Comparison

Monopar Therapeutics Inc. (MNPR) has a higher volatility of 14.39% compared to Calix, Inc. (CALX) at 9.55%. This indicates that MNPR's price experiences larger fluctuations and is considered to be riskier than CALX based on this measure. The chart below showcases a comparison of their rolling one-month volatility.

Volatility by Period

	MNPR	CALX	Difference
Volatility (1M) Calculated over the trailing 1-month period	14.39%	9.55%	+4.84%
Volatility (6M) Calculated over the trailing 6-month period	48.88%	29.75%	+19.13%
Volatility (1Y) Calculated over the trailing 1-year period	87.16%	39.70%	+47.46%
Volatility (5Y) Calculated over the trailing 5-year period, annualized	295.98%	49.59%	+246.39%
Volatility (10Y) Calculated over the trailing 10-year period, annualized	268.41%	51.20%	+217.21%

Financials