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MCRB vs. PALI
Performance
Return for Risk
Drawdowns
Volatility
Dividends
Financials

Performance

MCRB vs. PALI - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Seres Therapeutics, Inc. (MCRB) and Palisade Bio, Inc. (PALI). The values are adjusted to include any dividend payments, if applicable.

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Returns By Period

In the year-to-date period, MCRB achieves a -58.94% return, which is significantly lower than PALI's -16.60% return. Over the past 10 years, MCRB has outperformed PALI with an annualized return of -37.26%, while PALI has yielded a comparatively lower -69.85% annualized return.


MCRB

1D
-9.35%
1M
7.19%
6M
-60.96%
YTD
-58.94%
1Y
-51.39%
3Y*
-59.76%
5Y*
-57.21%
10Y*
-37.26%

PALI

1D
-0.51%
1M
14.62%
6M
-1.51%
YTD
-16.60%
1Y
160.29%
3Y*
-58.28%
5Y*
-76.68%
10Y*
-69.85%
*Multi-year figures are annualized to reflect compound growth (CAGR)

MCRB vs. PALI - Yearly Performance Comparison


2026 (YTD)202520242023202220212020201920182017
MCRB
Seres Therapeutics, Inc.
-58.94%-10.47%-40.64%-75.00%-32.77%-66.00%610.14%-23.67%-55.42%2.42%
PALI
Palisade Bio, Inc.
-16.60%42.42%-81.36%-88.65%-92.00%-75.38%-11.11%-84.19%-81.80%-51.61%

Correlation

The correlation between MCRB and PALI is 0.23, which is low. Their price movements are largely independent, making them effective diversification partners.


Correlation
Correlation (1Y)
Calculated over the trailing 1-year period

0.23

Correlation (3Y)
Calculated over the trailing 3-year period

0.17

Correlation (5Y)
Calculated over the trailing 5-year period

0.18

Correlation (10Y)
Calculated over the trailing 10-year period

0.16

Correlation (All Time)
Calculated using the full available price history since Jun 26, 2015

0.17

Fundamentals

Market Cap

MCRB:

$59.17M

PALI:

$340.22M

EPS

MCRB:

-$5.17

PALI:

-$0.27

PB Ratio

MCRB:

2.21

PALI:

3.23

Total Revenue (TTM)

MCRB:

$1.15M

PALI:

$0.00

Gross Profit (TTM)

MCRB:

$183.00K

PALI:

$0.00

EBITDA (TTM)

MCRB:

-$47.68M

PALI:

-$26.58M

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Seres Therapeutics, Inc.

Palisade Bio, Inc.

Return for Risk

MCRB vs. PALI — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

MCRB
MCRB Risk / Return Rank: 2525
Overall Rank
MCRB Sharpe Ratio Rank: 2222
Sharpe Ratio Rank
MCRB Sortino Ratio Rank: 2828
Sortino Ratio Rank
MCRB Omega Ratio Rank: 2727
Omega Ratio Rank
MCRB Calmar Ratio Rank: 2222
Calmar Ratio Rank
MCRB Martin Ratio Rank: 2424
Martin Ratio Rank

PALI
PALI Risk / Return Rank: 8383
Overall Rank
PALI Sharpe Ratio Rank: 8080
Sharpe Ratio Rank
PALI Sortino Ratio Rank: 8787
Sortino Ratio Rank
PALI Omega Ratio Rank: 8282
Omega Ratio Rank
PALI Calmar Ratio Rank: 8484
Calmar Ratio Rank
PALI Martin Ratio Rank: 8181
Martin Ratio Rank
The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

MCRB vs. PALI - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Seres Therapeutics, Inc. (MCRB) and Palisade Bio, Inc. (PALI). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Values are calculated on a 1-year rolling basis and updated daily. Risk-adjusted metrics are more stable over longer periods — use the period switch above to explore them.


MCRBPALIDifference
Sharpe ratioReturn per unit of total volatility

-1.72

Sortino ratioReturn per unit of downside risk

-2.76

Omega ratioGain probability vs. loss probability

0.96

1.28

-0.31

Calmar ratioReturn relative to maximum drawdown

-0.63

2.69

-3.32

Martin ratioReturn relative to average drawdown

-0.98

5.42

-6.40

MCRB vs. PALI - Sharpe Ratio Comparison

The current MCRB Sharpe Ratio is -0.51, which is lower than the PALI Sharpe Ratio of 1.21. The chart below compares the historical Sharpe Ratios of MCRB and PALI, calculated using daily returns over the previous 12 months. A higher Sharpe Ratio indicates better risk-adjusted performance relative to the risk-free rate.


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Drawdowns

MCRB vs. PALI - Drawdown Comparison

The maximum MCRB drawdown since its inception was -99.45%, roughly equal to the maximum PALI drawdown of -100.00%. Use the drawdown chart below to compare losses from any high point for MCRB and PALI.


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Drawdown Indicators


MCRBPALIDifference

Max Drawdown

Largest peak-to-trough decline

-99.45%

-100.00%

+0.55%

Max Drawdown (1Y)

Largest decline over 1 year

-80.37%

-56.53%

-23.84%

Max Drawdown (3Y)

Largest decline over 3 years

-94.46%

-98.44%

+3.98%

Max Drawdown (5Y)

Largest decline over 5 years

-98.65%

-99.98%

+1.33%

Max Drawdown (10Y)

Largest decline over 10 years

-99.26%

-100.00%

+0.74%

Current Drawdown

Current decline from peak

-99.41%

-100.00%

+0.59%

Average Drawdown

Average peak-to-trough decline

-81.53%

-76.39%

-5.14%

Ulcer Index

Depth and duration of drawdowns from previous peaks

51.79%

28.01%

+23.78%

Volatility

MCRB vs. PALI - Volatility Comparison

Seres Therapeutics, Inc. (MCRB) has a higher volatility of 27.56% compared to Palisade Bio, Inc. (PALI) at 25.61%. This indicates that MCRB's price experiences larger fluctuations and is considered to be riskier than PALI based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


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Volatility by Period


MCRBPALIDifference

Volatility (1M)

Calculated over the trailing 1-month period

27.56%

25.61%

+1.95%

Volatility (6M)

Calculated over the trailing 6-month period

70.63%

62.43%

+8.20%

Volatility (1Y)

Calculated over the trailing 1-year period

99.11%

126.15%

-27.04%

Volatility (5Y)

Calculated over the trailing 5-year period, annualized

105.20%

145.92%

-40.72%

Volatility (10Y)

Calculated over the trailing 10-year period, annualized

154.29%

140.93%

+13.36%

Dividends

MCRB vs. PALI - Dividend Comparison

Neither MCRB nor PALI has paid dividends to shareholders.


Tickers have no history of dividend payments

Financials

MCRB vs. PALI - Financials Comparison

This section allows you to compare key financial metrics between Seres Therapeutics, Inc. and Palisade Bio, Inc.. You can select fields from income statements, balance sheets, and cash flow statements to easily visualize and compare the financial health of both companies.


Quarterly
Annual

Total Revenue: Total amount of money received from sales and other business activities


0.0020.00M40.00M60.00M80.00M100.00M120.00MJulyOctober2022AprilJulyOctober2023AprilJulyOctober2024AprilJulyOctober2025AprilJulyOctober2026
358.00K
0
(MCRB) Total Revenue
(PALI) Total Revenue
Values in USD except per share items

Frequently Asked Questions


MCRB and PALI have a correlation of 0.23, meaning they provide meaningful diversification benefit when combined. Depending on your allocation goals, holding both could reduce overall portfolio risk.

MCRB has higher volatility (27.56%) compared to PALI (25.61%). In terms of maximum drawdown, MCRB dropped -99.45% vs PALI's -100.00%.

PALI currently has the higher Sharpe Ratio (1.21 vs -0.51), meaning it's delivered slightly more return per unit of risk over the trailing 12 months. However, this ranking shifts over time - use the Risk/Return Score above for a more comprehensive view that combines Sharpe, Sortino, and other measures used by quantitative funds.

Portfolio Optimizer

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