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LXRX vs. SPY
Performance
Risk-Adjusted Performance
Dividends
Drawdowns
Volatility

Correlation

The correlation between LXRX and SPY is 0.39, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.


-0.50.00.51.00.4

Performance

LXRX vs. SPY - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Lexicon Pharmaceuticals, Inc. (LXRX) and SPDR S&P 500 ETF (SPY). The values are adjusted to include any dividend payments, if applicable.

-60.00%-40.00%-20.00%0.00%20.00%40.00%AugustSeptemberOctoberNovemberDecember2025
-41.80%
6.59%
LXRX
SPY

Key characteristics

Sharpe Ratio

LXRX:

-0.36

SPY:

2.17

Sortino Ratio

LXRX:

0.10

SPY:

2.88

Omega Ratio

LXRX:

1.01

SPY:

1.40

Calmar Ratio

LXRX:

-0.37

SPY:

3.26

Martin Ratio

LXRX:

-0.72

SPY:

14.09

Ulcer Index

LXRX:

51.50%

SPY:

1.95%

Daily Std Dev

LXRX:

102.49%

SPY:

12.64%

Max Drawdown

LXRX:

-99.80%

SPY:

-55.19%

Current Drawdown

LXRX:

-99.72%

SPY:

-2.83%

Returns By Period

In the year-to-date period, LXRX achieves a 25.92% return, which is significantly higher than SPY's 0.44% return. Over the past 10 years, LXRX has underperformed SPY with an annualized return of -17.77%, while SPY has yielded a comparatively higher 13.15% annualized return.


LXRX

YTD

25.92%

1M

31.88%

6M

-41.88%

1Y

-39.22%

5Y*

-25.71%

10Y*

-17.77%

SPY

YTD

0.44%

1M

-2.83%

6M

6.59%

1Y

25.62%

5Y*

14.26%

10Y*

13.15%

*Annualized

Compare stocks, funds, or ETFs

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Risk-Adjusted Performance

LXRX vs. SPY — Risk-Adjusted Performance Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

LXRX
The Risk-Adjusted Performance Rank of LXRX is 3131
Overall Rank
The Sharpe Ratio Rank of LXRX is 2828
Sharpe Ratio Rank
The Sortino Ratio Rank of LXRX is 3636
Sortino Ratio Rank
The Omega Ratio Rank of LXRX is 3636
Omega Ratio Rank
The Calmar Ratio Rank of LXRX is 2525
Calmar Ratio Rank
The Martin Ratio Rank of LXRX is 3232
Martin Ratio Rank

SPY
The Risk-Adjusted Performance Rank of SPY is 8484
Overall Rank
The Sharpe Ratio Rank of SPY is 8484
Sharpe Ratio Rank
The Sortino Ratio Rank of SPY is 8282
Sortino Ratio Rank
The Omega Ratio Rank of SPY is 8383
Omega Ratio Rank
The Calmar Ratio Rank of SPY is 8383
Calmar Ratio Rank
The Martin Ratio Rank of SPY is 8585
Martin Ratio Rank
The risk-adjusted ranks indicate the investment's position relative to the market. A rank closer to 100 signifies top-performing investments, while a rank closer to 0 might suggest underperformance, based on the selected ratio. The values are calculated based on the past 12 months of returns.

LXRX vs. SPY - Risk-Adjusted Performance Comparison

This table presents a comparison of risk-adjusted performance metrics for Lexicon Pharmaceuticals, Inc. (LXRX) and SPDR S&P 500 ETF (SPY). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.


Sharpe ratio
The chart of Sharpe ratio for LXRX, currently valued at -0.36, compared to the broader market-4.00-2.000.002.00-0.362.17
The chart of Sortino ratio for LXRX, currently valued at 0.10, compared to the broader market-4.00-2.000.002.004.000.102.88
The chart of Omega ratio for LXRX, currently valued at 1.01, compared to the broader market0.501.001.502.001.011.40
The chart of Calmar ratio for LXRX, currently valued at -0.37, compared to the broader market0.002.004.006.00-0.373.26
The chart of Martin ratio for LXRX, currently valued at -0.72, compared to the broader market-10.000.0010.0020.00-0.7214.09
LXRX
SPY

The current LXRX Sharpe Ratio is -0.36, which is lower than the SPY Sharpe Ratio of 2.17. The chart below compares the historical Sharpe Ratios of LXRX and SPY, offering insights into how both investments have performed under varying market conditions. These values are calculated using daily returns over the previous 12 months.


Rolling 12-month Sharpe Ratio-1.000.001.002.003.004.00AugustSeptemberOctoberNovemberDecember2025
-0.36
2.17
LXRX
SPY

Dividends

LXRX vs. SPY - Dividend Comparison

LXRX has not paid dividends to shareholders, while SPY's dividend yield for the trailing twelve months is around 1.20%.


TTM20242023202220212020201920182017201620152014
LXRX
Lexicon Pharmaceuticals, Inc.
0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%0.00%
SPY
SPDR S&P 500 ETF
1.20%1.21%1.40%1.65%1.20%1.52%1.75%2.04%1.80%2.03%2.06%1.87%

Drawdowns

LXRX vs. SPY - Drawdown Comparison

The maximum LXRX drawdown since its inception was -99.80%, which is greater than SPY's maximum drawdown of -55.19%. Use the drawdown chart below to compare losses from any high point for LXRX and SPY. For additional features, visit the drawdowns tool.


-100.00%-80.00%-60.00%-40.00%-20.00%0.00%AugustSeptemberOctoberNovemberDecember2025
-99.72%
-2.83%
LXRX
SPY

Volatility

LXRX vs. SPY - Volatility Comparison

Lexicon Pharmaceuticals, Inc. (LXRX) has a higher volatility of 36.12% compared to SPDR S&P 500 ETF (SPY) at 4.49%. This indicates that LXRX's price experiences larger fluctuations and is considered to be riskier than SPY based on this measure. The chart below showcases a comparison of their rolling one-month volatility.


0.00%10.00%20.00%30.00%40.00%50.00%AugustSeptemberOctoberNovemberDecember2025
36.12%
4.49%
LXRX
SPY
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Disclaimer

The information contained herein does not constitute investment advice and made available for educational purposes only. Prices and returns on equities are listed without consideration of fees, commissions, taxes, penalties, or interest payable due to purchasing, holding, or selling.

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