LABP vs. SLNO

Last updated Apr 1, 2026

Compare and contrast key facts about Landos Biopharma, Inc. (LABP) and Soleno Therapeutics, Inc. (SLNO).

Performance

LABP vs. SLNO - Performance Comparison

The chart below illustrates the hypothetical performance of a $10,000 investment in Landos Biopharma, Inc. (LABP) and Soleno Therapeutics, Inc. (SLNO). The values are adjusted to include any dividend payments, if applicable.

LABP vs. SLNO - Yearly Performance Comparison

	2026 (YTD)	2025	2024	2023	2022	2021
LABP Landos Biopharma, Inc.	0.00%	0.00%	526.50%	-26.81%	-89.58%	-60.00%
SLNO Soleno Therapeutics, Inc.	-27.69%	3.00%	11.68%	1,932.83%	-67.80%	-85.04%

Fundamentals

Total Revenue (TTM) LABP : $0.00 SLNO : $190.41M
Gross Profit (TTM) LABP : $0.00 SLNO : $96.84M
EBITDA (TTM) LABP : -$24.41M SLNO : $9.41M

Returns By Period

LABP

• 1D: —
• 1M: —
• YTD: —
• 6M: —
• 1Y: —
• 3Y*: —
• 5Y*: —
• 10Y*: —

SLNO

• 1D: 9.99%
• 1M: -14.31%
• YTD: -27.69%
• 6M: -50.47%
• 1Y: -53.14%
• 3Y*: 150.11%
• 5Y*: 11.25%
• 10Y*: -9.78%

*Multi-year figures are annualized to reflect compound growth (CAGR)

Return for Risk

LABP vs. SLNO — Risk / Return Rank

Compare risk-adjusted metric ranks to identify better-performing investments over the past 12 months.

SLNO

SLNO Risk / Return Rank: 10
SLNO Sharpe Ratio Rank: 8
SLNO Sortino Ratio Rank: 10
SLNO Omega Ratio Rank: 10
SLNO Calmar Ratio Rank: 12
SLNO Martin Ratio Rank: 10

The rank (0–100) shows how this investment's returns compare to the risk taken. Higher = better. Based on the past 12 months of data, combining Sharpe, Sortino, and other metrics used by quantitative funds and institutional investors.

LABP vs. SLNO - Risk-Adjusted Trends Comparison

This table presents a comparison of risk-adjusted performance metrics for Landos Biopharma, Inc. (LABP) and Soleno Therapeutics, Inc. (SLNO). Risk-adjusted metrics are performance indicators that assess an investment's returns in relation to its risk, enabling a more accurate comparison of different investment options.

Risk / return metrics aren't available yet — we need at least 12 months of trading data to calculate them.

Sharpe Ratios by Period

	LABP	SLNO	Difference
Sharpe Ratio (1Y) Calculated over the trailing 1-year period	—	-0.83	—
Sharpe Ratio (5Y) Calculated over the trailing 5-year period	—	0.05	—
Sharpe Ratio (10Y) Calculated over the trailing 10-year period	—	-0.05	—
Sharpe Ratio (All Time) Calculated using the full available price history	—	-0.09	—

Correlation

The correlation between LABP and SLNO is 0.16, which is considered to be low. This implies their price changes are not closely related. A low correlation is generally favorable for portfolio diversification, as it helps to reduce overall risk by spreading it across multiple assets with different performance patterns.

Dividends

LABP vs. SLNO - Dividend Comparison

Neither LABP nor SLNO has paid dividends to shareholders.

Tickers have no history of dividend payments

Drawdowns

Drawdown Indicators

	LABP	SLNO	Difference
Max Drawdown Largest peak-to-trough decline	—	-99.86%	—
Max Drawdown (1Y) Largest decline over 1 year	—	-66.04%	—
Max Drawdown (5Y) Largest decline over 5 years	—	-95.49%	—
Max Drawdown (10Y) Largest decline over 10 years	—	-99.13%	—
Current Drawdown Current decline from peak	—	-94.90%	—
Average Drawdown Average peak-to-trough decline	—	-90.57%	—
Ulcer Index Depth and duration of drawdowns from previous peaks	—	35.50%	—

Volatility

Volatility by Period

	LABP	SLNO	Difference
Volatility (1M) Calculated over the trailing 1-month period	—	17.95%	—
Volatility (6M) Calculated over the trailing 6-month period	—	50.62%	—
Volatility (1Y) Calculated over the trailing 1-year period	—	64.08%	—
Volatility (5Y) Calculated over the trailing 5-year period, annualized	—	243.38%	—
Volatility (10Y) Calculated over the trailing 10-year period, annualized	—	185.10%	—

Financials